[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584175":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":32,"responsibleParty":50,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":10,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":74,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"ALS Therapy Development Institute","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Person living with ALS\u002FMND",null,"An adult over the age of 18, that has received a diagnosis of ALS or other Motor Neuron Disease from a practicing physician.",{"label":13,"type":10,"description":14,"interventionNames":10},"Asymptomatic gene carrier","An adult over the age of 18 who does not have symptoms of ALS and carries a mutation known to be associated with ALS",{"label":16,"type":10,"description":17,"interventionNames":10},"Healthy Volunteer","An adult over the age of 18 who does not have any biological connection to ALS or other Motor Neuron Disease, and no significant health problems.",[19],{"name":20,"affiliation":5,"role":21},"Fernando G Vieira, M.D.","PRINCIPAL_INVESTIGATOR",[23,29],{"name":24,"role":25,"phone":26,"phoneExt":27,"email":28},"Alan S Premasiri, M.S.","CONTACT","617-441-7200","7291","apremasiri@als.net",{"name":30,"role":25,"phone":26,"phoneExt":10,"email":31},"Beth Levine","blevine@als.net",[33],{"facility":5,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Watertown","Massachusetts","02472","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-71.18283,42.37093,{"lat":44,"lon":43},[47,49],{"name":24,"role":25,"phone":48,"phoneExt":27,"email":28},"6174417200",{"name":20,"role":21,"phone":10,"phoneExt":10,"email":10},{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100584175","als-research-collaborative-100584175",false,"NCT06885918","ALS Research Collaborative","ALS Translational Research Program","ARC","Inclusion Criteria:\n\n* 18 years of age or older\n* Can communicate in written English\n* Has a diagnosis of ALS\u002FMND or is a known carrier of an ALS associated mutation\n\nExclusion Criteria:\n\n* Significant cognitive impairment that would prevent individual completion and understanding of the informed consent process.",true,"ALL","18 Years",{"count":64,"type":65},2000,"ESTIMATED","OBSERVATIONAL","The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings will help with drug discovery, biomarker discovery, and outcome measure validation. Adults living with ALS, other motor neuron diseases (MND), a known mutation related to ALS and healthy volunteers contribute prospective and retrospective data to this study remotely. The study is sponsored and conducted by the ALS Therapy Development Institute.",[69,70,71,72,73],"Amyotrophic Lateral Sclerosis","ALS (Amyotrophic Lateral Sclerosis)","ALS With Frontotemporal Dementia (ALS\u002FFTD)","Motor Neuron Disease","Motor Neuron Disease, Amyotrophic Lateral Sclerosis",[58,56,75,76],"ALS TDI","ALS Therapy Develeopment Institute","2025-03-13",{"date":79,"type":80},"2025-03-20","ACTUAL",{"date":82,"type":80},"2014-09-12",{"date":84,"type":65},"2035-01-31",{"name":5,"class":6},1]