[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487853":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":28,"locations":37,"responsibleParty":51,"collaborators":53,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":10,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Anorexia patients",null,"Hospitalized anorexia patients with body mass index \\\u003C 15.",[13],"Biological: Stool and blood samples",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy controls","Health volunteers: 18 years or older with body mass index between 18.5 and 25.",[13],[19],{"type":20,"name":21,"description":21,"armGroupLabels":22,"otherNames":10},"BIOLOGICAL","Stool and blood samples",[9,15],[24],{"name":25,"affiliation":26,"role":27},"Mouna HANACHI GUIDOUM, MD","Service de Nutrition Clinique, Hôpital Paul Brousse - APHP","PRINCIPAL_INVESTIGATOR",[29,33],{"name":25,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","+ 33 6 70 39 42 37","mouna.hanachi@aphp.fr",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Joël DORE","+ 33 1 34 65 27 09","joel.dore@jouy.inrae.fr",[38],{"facility":39,"status":40,"city":41,"state":10,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":10},"Service de Nutrition Clinique, Hôpital Paul Brousse (APHP)","RECRUITING","Villejuif","94800","France","FR",{"type":46,"coordinates":47},"Point",[48,49],2.35992,48.7939,{"lat":49,"lon":48},{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[54],{"name":55,"class":6},"Fondation de France","100487853","alteration-of-symbiosis-intestinal-microbiota-on-patients-with-anorexia-nervosa-100487853",false,"NCT05632497","Alteration of Symbiosis Intestinal Microbiota on Patients With Anorexia Nervosa","Study of Translational Process of Relationship Between Intestinal Microbiota of Dysbiosis and the Psychic Symptoms of Anorexia Nervosa (Eating Disorders and Anxio-depression Disorders)","INT-METAVOSA","Inclusion Criteria:\n\nFor patients:\n\n* Patients aged ≥18 years;\n* Anorexia according to DSM-5 and CIDI (Composite International Diagnostic Interview);\n* Body mass index (BMI) (P\u002FT2) \\\u003C 15;\n* Hospitalization for nutrition rehabilitation;\n* Covered by a health insurance;\n* Informed consent form signed.\n\nFor Healthy Volunteers:\n\n* Aged ≥18 years;\n* 18.5 \\\u003C BMI (P\u002FT2) \\\u003C 25;\n* Covered by a health insurance;\n* Informed consent form signed.\n\nExclusion Criteria:\n\nFor patients:\n\n* Patients no-responding all criteria of DSM-5 or CIDI scores;\n* Taken of antibiotic treatment 2 months \u002F or laxativ 3 weeks before hospitalization;\n* Somatic comorbidity should perturb intestinal microbiota (Crohn's disease, diabetes and all other chronic inflammatory diseases);\n* Patients under guardianship;\n* Patients covered by french AME scheme.\n\nFor Healthy Volunteers:\n\n* Any disease should perturb intestinal microbiota;\n* Recent ponderal variation;\n* Taken of antibiotic treatment 2 months or laxativ 3 weeks before hospitalization;\n* Under guardianship;\n* Covered by french AME scheme.",true,"ALL","18 Years",{"count":68,"type":69},120,"ESTIMATED","OBSERVATIONAL","The purpose of this study will be to study the association between the level of psychic symptomatic of anorexia nervosa (AN) (intensity of food restriction, symptoms of anxiety and depression) and alteration of host environment symbiosis and the mechanism (dysbiosis of intestinal microbiota, increase of intestinal permeability, immunity alteration and low-grade inflammation).",[73,74,75],"Anorexia Nervosa","Dysbiosis","Anxious Depression",[77,74,78,79,80],"Anorexia nervosa","Anxious depression","Intestinal microbiota","Body mass index","2025-11-19",{"date":83,"type":84},"2025-11-24","ACTUAL",{"date":86,"type":84},"2024-05-23",{"date":88,"type":69},"2026-10",{"name":5,"class":6},1]