[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607839":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":10,"centralContacts":33,"locations":43,"responsibleParty":304,"collaborators":306,"id":311,"slug":312,"hasResults":313,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":317,"eligibilityCriteria":318,"healthyVolunteers":313,"sex":319,"minAge":320,"maxAge":321,"enrollmentInfo":322,"targetDuration":10,"studyType":325,"phases":10,"briefSummary":326,"conditions":327,"keywords":10,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":335,"completionDateStruct":337,"leadSponsor":339,"locationsCount":340},{"fullName":5,"class":6},"Latin American Pediatric Collaborative Network","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Altitude PICUs",null,"Children with PARDS admitted to pediatric intensive care units located at altitudes between 0-1500 meters above sea level.",[13],"Other: Geographic Altitude",{"label":15,"type":10,"description":16,"interventionNames":17},"Intermediate Altitude PICUs","Children with PARDS admitted to pediatric intensive care units located at altitudes between 1501-2500 meters above sea level.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"High Altitude PICUs","Children with PARDS admitted to pediatric intensive care units located at altitudes between 2501-3500 meters above sea level.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Very High Altitude PICUs","Children with PARDS admitted to pediatric intensive care units located at altitudes above 3500 meters above sea level.",[13],[27],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Geographic Altitude","Participants are grouped according to the altitude of the pediatric intensive care unit (PICU) where they are admitted: low altitude (0-1500 m), intermediate altitude (1501-2500 m), high altitude (2501-3500 m), and very high altitude (\\>3500 m). Altitude is treated as the primary exposure variable. No therapeutic intervention is administered as part of this study.",[19,15,9,23],[32],"Altitude Exposure",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"PABLO VASQUEZ-HOYOS, MD, MSc","CONTACT","573187172029","pablovasquezmd@gmail.com",{"name":40,"role":36,"phone":41,"phoneExt":10,"email":42},"SEBASTIAN GONZALEZ-DAMBRAUSKAS, MD","59899585225","sgdambrauskas@gmail.com",[44,62,76,90,104,119,136,147,158,168,176,185,195,209,224,239,250,266,279,294],{"facility":45,"status":46,"city":47,"state":48,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Hospital del Niño Sor Teresa Huarte Tama","RECRUITING","Sucre","Chuquisaca Department","Bolivia","BO",{"type":52,"coordinates":53},"Point",[54,55],-65.26274,-19.03332,{"lat":55,"lon":54},[58],{"name":59,"role":36,"phone":60,"phoneExt":10,"email":61},"Jhovana Elizabeth Paco Barral, 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Dios","Tarija","Tarija Department",{"type":52,"coordinates":95},[96,97],-64.72956,-21.53549,{"lat":97,"lon":96},[100],{"name":101,"role":36,"phone":102,"phoneExt":10,"email":103},"Nils Casson, MD","+59176187393","nilsjefe1@hotmail.com",{"facility":105,"status":46,"city":106,"state":10,"zip":10,"country":107,"countryCode":108,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Clinica Indisa","Santiago","Chile","CL",{"type":52,"coordinates":110},[111,112],-70.64827,-33.45694,{"lat":112,"lon":111},[115],{"name":116,"role":36,"phone":117,"phoneExt":10,"email":118},"Victor Monreal, MD","+5693373202","victor.monreal@indisa.cl",{"facility":120,"status":46,"city":121,"state":122,"zip":123,"country":124,"countryCode":125,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"Hospital Universitario Clinica San 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Ignacio",{"type":52,"coordinates":179},[128,129],{"lat":129,"lon":128},[182],{"name":183,"role":36,"phone":10,"phoneExt":10,"email":184},"Deyanira Quiñones, MD","adquinonez@husi.org.co",{"facility":186,"status":46,"city":121,"state":122,"zip":10,"country":124,"countryCode":125,"cosmosGeoPoint":187,"geoPoint":189,"contacts":190},"Los Cobos Medical Center",{"type":52,"coordinates":188},[128,129],{"lat":129,"lon":128},[191],{"name":192,"role":36,"phone":193,"phoneExt":10,"email":194},"Andrea Rodríguez Mayorga, MD","+573142128477","andrerodriguezmayorga@gmail.com",{"facility":196,"status":46,"city":197,"state":198,"zip":199,"country":124,"countryCode":125,"cosmosGeoPoint":200,"geoPoint":204,"contacts":205},"Fundacion Hospital Infantil Los Angeles","Pasto","Departamento de Nariño","520002",{"type":52,"coordinates":201},[202,203],-77.27846,1.21456,{"lat":203,"lon":202},[206],{"name":207,"role":36,"phone":10,"phoneExt":10,"email":208},"Liliana Mazzillo, MD","lilianamazzillo@gmail.com",{"facility":210,"status":46,"city":211,"state":212,"zip":213,"country":124,"countryCode":125,"cosmosGeoPoint":214,"geoPoint":218,"contacts":219},"Clínica UROS S.A","Neiva","Huila Department","410010",{"type":52,"coordinates":215},[216,217],-75.27973,2.93001,{"lat":217,"lon":216},[220],{"name":221,"role":36,"phone":222,"phoneExt":10,"email":223},"Ivan Ardila, MD","+573174301866","ivanjoardila@hotmail.com",{"facility":225,"status":226,"city":227,"state":228,"zip":10,"country":124,"countryCode":125,"cosmosGeoPoint":229,"geoPoint":233,"contacts":234},"Fundación Valle de Lili","NOT_YET_RECRUITING","Cali","Valle del Cauca Department",{"type":52,"coordinates":230},[231,232],-76.5199,3.43054,{"lat":232,"lon":231},[235],{"name":236,"role":36,"phone":237,"phoneExt":10,"email":238},"Ruben Lasso, 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Adolfo Guevara Velasco","Cusco",{"type":52,"coordinates":270},[271,272],-71.96701,-13.53188,{"lat":272,"lon":271},[275],{"name":276,"role":36,"phone":277,"phoneExt":10,"email":278},"Yesica Luna, MD","+51992818282","yesilunde@hotmail.com",{"facility":280,"status":46,"city":281,"state":282,"zip":283,"country":284,"countryCode":285,"cosmosGeoPoint":286,"geoPoint":290,"contacts":291},"Centro Hospitalario Pereira Rossell","Montevideo","Montevideo Department","11600","Uruguay","UY",{"type":52,"coordinates":287},[288,289],-56.18816,-34.90328,{"lat":289,"lon":288},[292],{"name":40,"role":36,"phone":293,"phoneExt":10,"email":42},"+5759899585225",{"facility":295,"status":46,"city":281,"state":10,"zip":10,"country":284,"countryCode":285,"cosmosGeoPoint":296,"geoPoint":298,"contacts":299},"Círculo Católico",{"type":52,"coordinates":297},[288,289],{"lat":289,"lon":288},[300],{"name":301,"role":36,"phone":302,"phoneExt":10,"email":303},"Mónica Decia, MD","+59899664031","monicadecia@gmail.com",{"type":305,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[307,309],{"name":308,"class":6},"Universidad Nacional de Colombia",{"name":310,"class":6},"Fundación Universitaria de Ciencias de la Salud","100607839","altitude-and-outcomes-in-pediatric-ards-a-multicenter-study-100607839",false,"NCT07193771","Altitude and Outcomes in Pediatric ARDS: A Multicenter Study","Evaluation of Altitude as an Independent Risk Factor for Mortality in Pediatric Acute Respiratory Distress Syndrome: Influence of Oxygenation, Ventilation, and Hospital Structure in a Multicenter Observational Study.","LARed-ALT","Inclusion Criteria:\n\n* Age between 1 month (corrected gestational age) and 18 years.\n* Admission to a pediatric intensive care unit (PICU) or facility where mechanically ventilated children are cared for.\n* Requirement of invasive mechanical ventilation.\n* Diagnosis of pediatric acute respiratory distress syndrome (PARDS) according to PALICC criteria, confirmed within 24 hours before or after endotracheal intubation.\n\nExclusion Criteria:\n\n* Patients with active perinatal lung disease (e.g., neonatal respiratory distress syndrome, pulmonary hemorrhage, persistent pulmonary hypertension of the newborn, early bronchopulmonary dysplasia, meconium aspiration).\n* Patients who have received extracorporeal membrane oxygenation (ECMO) prior to or within the first 24 hours of PARDS diagnosis.\n* Patients with pre-established limitation of therapeutic effort (LTE) orders or palliative care directives documented before the initiation of invasive mechanical ventilation.\n* Readmissions to the PICU during the study period (only the first episode per patient will be included).","ALL","1 Month","18 Years",{"count":323,"type":324},1600,"ESTIMATED","OBSERVATIONAL","This multicenter observational study will evaluate the association between geographic altitude, availability of critical care resources, and clinical outcomes in children with pediatric acute respiratory distress syndrome (PARDS). Data on demographics, physiology, and hospital structure will be collected from PICUs located at different altitudes worldwide. The study aims to identify gaps in PARDS management and provide recommendations adapted to diverse resource settings.",[328,329,330],"Respiratory Distress Syndrome, Pediatric","Altitude Hypoxia","High Altitude Effects","2026-05-29",{"date":333,"type":334},"2026-06-02","ACTUAL",{"date":336,"type":334},"2025-11-01",{"date":338,"type":324},"2028-03",{"name":5,"class":6},20]