[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100336232":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":48,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":73,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Alzheimer's Light LLC","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants who adhere to the protocol",null,"All participants are encouraged to exercise with AlzLife daily for 30 minutes a day. The actual duration is to be measured through participant's interactions with ALZLIFE. Participants adhere to the protocol if they exercise with AlzLife the minimum of 1hour\u002Fweek.",[13],"Device: Combination of 40Hz light and cognitive therapy (ALZLIFE)",{"label":15,"type":10,"description":16,"interventionNames":17},"Participants who do not adhere to the protocol","All participants are encouraged to exercise with AlzLife daily for 30 minutes a day. The actual duration is to be measured through participant's interactions with ALZLIFE. Participants do not adhere to the protocol if they exercise with AlzLife less than 1hour\u002Fweek.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DEVICE","Combination of 40Hz light and cognitive therapy (ALZLIFE)","Combination of 40Hz light and cognitive therapy delivered by iPad application ALZLIFE",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Andrey Vyshedskiy, Ph.D.","CONTACT","(617) 433-7724","vysha@bu.edu",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Andrey Vyshedskiy","RECRUITING","Miami","Florida","33156","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-80.19366,25.77427,{"lat":43,"lon":42},[46],{"name":32,"role":27,"phone":47,"phoneExt":10,"email":29},"617-433-8577",{"type":49,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100336232","alzheimers-disease-treatment-with-combination-of-40hz-light-and-cognitive-therapy-100336232",false,"NCT03657745","Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy","An Observational Trial of Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy","AlzLife","Inclusion Criteria:\n\n* Alzheimer's disease\n* Cognitive Impairment\n\nExclusion Criteria:\n\n* any previously noted epileptic seizures, including febrile seizures.\n* any significant disease of the eye, such as macular degeneration. Since the 40Hz light therapy is delivered via eye stimulation, healthy eyes are required.",true,"ALL","50 Years",{"count":62,"type":63},2000,"ESTIMATED","OBSERVATIONAL","Electrical activity in the brain known as \"gamma\" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLife https:\u002F\u002Fwww.alz.life\u002F) that delivers light therapy at 40 Hz combined with cognitive therapy to improve cognition, function, and quality of life in Alzheimer's disease.",[67,68,69,70,71,72],"Alzheimer Disease","Mild Cognitive Impairment","Dementia","Cognition Disorders in Old Age","Cognitive Decline","Cognitive Deterioration",[67,74,69],"Alzheimer's","2024-07-31",{"date":77,"type":78},"2024-08-01","ACTUAL",{"date":80,"type":78},"2018-01-01",{"date":82,"type":63},"2029-12-31",{"name":5,"class":6},1]