[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580324":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":30,"responsibleParty":49,"collaborators":20,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":20,"enrollmentInfo":61,"targetDuration":20,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":20,"overallStatus":32,"whyStopped":20,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Karolinska University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All patients","EXPERIMENTAL","All patients will start CRRT treatment without amino acid supplementation After a few hours samples are drawn from blood and dialysate Patients then receive low dose of supplementation for 24 hours (33.5g, 250 ml Glavamin, Fresenius Kabi) and new samples are drawn After that patients receive full supplementation (67g, 500 ml Glavamin, Fresenius Kabi) for the rest the of CRRT treatment. After 24 hours of this treatment new samples are drawn.",[13],"Dietary Supplement: Amino acid supplementation (Glavamin, Fresenius Kabi)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIETARY_SUPPLEMENT","Amino acid supplementation (Glavamin, Fresenius Kabi)","Mixture of amino acids (67 g \u002F 500 ml) given intravenously",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Jonathan Grip, MD, PhD","PRINCIPAL_INVESTIGATOR",[26],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","+46736230906","jonathan.grip@regionstockholm.se",[31],{"facility":5,"status":32,"city":33,"state":20,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Stockholm","14186","Sweden","SE",{"type":38,"coordinates":39},"Point",[40,41],18.06871,59.32938,{"lat":41,"lon":40},[44,46],{"name":45,"role":27,"phone":28,"phoneExt":20,"email":29},"Jonathan Grip, MD,Phd",{"name":47,"role":27,"phone":20,"phoneExt":20,"email":48},"Kristina Kilsand, R-Nurse","kristina.kilsand@regionstockholm.se",{"type":24,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Jonathan Grip","MD, PhD","100580324","amino-acid-supplementation-in-continuous-renal-replacement-therapy-100580324",false,"NCT06835816","Amino Acid Supplementation in Continuous Renal Replacement Therapy","AARRT","Inclusion Criteria:\n\n* Dialysis where amino acid supplementation is planned by treating physician\n\nExclusion Criteria:\n\n* Liver failure\n* Muscle disease\n* Neurodegenerative disease","ALL","18 Years",{"count":62,"type":63},30,"ESTIMATED","INTERVENTIONAL",[66],"NA","ICU patients treated with continuous renal replacement therapy is recruited prior to start of treatment.\n\nBlood samples are drawn and then dialysis start without amino acid supplementation. After a few hours samples are drawn from blood and dialysate. Then patients are given amino acid supplementation (33.5g\u002F24hrs) for 20-24 hours. New samples are drawn and amino acid supplementation is increased to 67g\u002F24hrs and new samples are drawn after additional 24 hours. Then CRRT will continue with the full amino acid supplementation (standars of care).",[69],"Acute Kidney Injury","2025-02-14",{"date":72,"type":73},"2025-02-19","ACTUAL",{"date":75,"type":73},"2025-02-03",{"date":77,"type":63},"2028-12-31",{"name":5,"class":6},1]