[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544320":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":56,"collaborators":58,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":12,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":12,"enrollmentInfo":72,"targetDuration":12,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":12,"overallStatus":41,"whyStopped":12,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Comparison","NO_INTERVENTION","Standard of care, e.g. regular HIV care plus brief advice on alcohol use",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Mlambe Intervention","EXPERIMENTAL","A couples-based intervention to reduce problematic drinking and improve economic and HIV outcomes.",[18],"Behavioral: Mlambe",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","Mlambe","A combined economic and relationship-strengthening intervention. Sessions consist of incentivized savings accounts, financial literacy training, and relationships skills building, including couple communication.",[14],[26],{"name":27,"affiliation":5,"role":28},"Amy Conroy, PhD","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},"James Mkandawire","CONTACT","+265 8883 70081","james3mkandawire@gmail.com",{"name":27,"role":32,"phone":36,"phoneExt":12,"email":37},"415-476-6021","Amy.conroy@ucsf.edu",[39],{"facility":40,"status":41,"city":42,"state":12,"zip":12,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Invest in Knowledge Initiative (IKI)","RECRUITING","Zomba","Malawi","MW",{"type":46,"coordinates":47},"Point",[48,49],35.3188,-15.38596,{"lat":49,"lon":48},[52,54],{"name":31,"role":32,"phone":12,"phoneExt":12,"email":53},"james.mkandawire@investinknowledge.org",{"name":12,"role":32,"phone":55,"phoneExt":12,"email":12},"0888370081",{"type":57,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[59],{"name":60,"class":61},"National Institute on Alcohol Abuse and Alcoholism (NIAAA)","NIH","100544320","an-economic-and-relationship-strengthening-intervention-to-reduce-alcohol-use-in-malawi-100544320",false,"NCT06367348","An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi","Mlambe: A Randomized Controlled Trial of an Economic and Relationship-Strengthening Intervention to Reduce Alcohol Use in Malawi","Inclusion Criteria:\n\n1. In a married or cohabitating union\n2. Have at least one partner with a positive AUDIT-C screen in prior 3 months\n3. Must also currently be on ART for at least 6 months\n4. Must have disclosed their HIV status to their partner\n\nExclusion Criteria:\n\n1\\) Severe intimate partner violence reported in previous 3 months and\u002For fear that safety would be at risk by participation in the study (reported at screening). Couples who participated in Mlambe's pilot study will also be excluded.",true,"ALL","18 Years",{"count":73,"type":74},500,"ESTIMATED","INTERVENTIONAL",[77],"NA","With a full-scale randomized control trial, the investigators will evaluate the efficacy and cost effectiveness of Mlambe, an economic and relationship-strengthening intervention that provides incentivized saving accounts, financial literacy training, and relationship skills education to break the cycle of poverty around drinking, strengthen couple support and communication, and reduce heavy drinking among HIV-affected married couples with a partner who drinks alcohol in Malawi.",[80,81],"HIV\u002FAIDS","Alcohol Abuse","2026-05-11",{"date":84,"type":85},"2026-05-14","ACTUAL",{"date":87,"type":85},"2025-02-14",{"date":89,"type":74},"2028-05",{"name":5,"class":6},1]