[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550197":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":21,"locations":30,"responsibleParty":459,"collaborators":7,"id":461,"slug":462,"hasResults":463,"nctId":464,"briefTitle":465,"officialTitle":466,"acronym":7,"eligibilityCriteria":467,"healthyVolunteers":463,"sex":468,"minAge":469,"maxAge":7,"enrollmentInfo":7,"targetDuration":7,"studyType":470,"phases":7,"briefSummary":471,"conditions":472,"keywords":477,"overallStatus":33,"whyStopped":7,"lastUpdateSubmitDate":480,"lastUpdatePostDateStruct":481,"startDateStruct":7,"completionDateStruct":7,"leadSponsor":484,"locationsCount":485},{"fullName":5,"class":6},"CG Oncology, Inc.","INDUSTRY",null,[9,15],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":13},"DRUG","Cretostimogene Grenadenorepvec","Engineered Oncolytic Adenovirus",[14],"CG0070",{"type":16,"name":17,"description":18,"armGroupLabels":7,"otherNames":19},"OTHER","n-dodecyl-B-D-maltoside","Transduction-enhancing agent",[20],"DDM",[22,27],{"name":23,"role":24,"phone":25,"phoneExt":7,"email":26},"Rob Svatek, MD","CONTACT","(949) 419-6203","recruitment@cgoncology.com",{"name":28,"role":24,"phone":29,"phoneExt":7,"email":26},"Vijay Kasturi, MD","949-409-3700",[31,56,73,88,104,120,136,154,168,185,201,216,232,248,264,280,296,312,327,343,359,378,393,411,426,442],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Banner MD Anderson Cancer Center","AVAILABLE","Gilbert","Arizona","85234","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-111.78903,33.35283,{"lat":43,"lon":42},[46,50,53],{"name":47,"role":24,"phone":48,"phoneExt":7,"email":49},"Joseph Mashni","206-210-4040","Joseph.Mashni@bannerhealth.com",{"name":51,"role":24,"phone":7,"phoneExt":7,"email":52},"Gabrielle Santor","Gabrielle.Santor@bannerhealth.com",{"name":54,"role":55,"phone":7,"phoneExt":7,"email":7},"Chinedu Mmeje, MD","PRINCIPAL_INVESTIGATOR",{"facility":57,"status":33,"city":58,"state":59,"zip":60,"country":37,"countryCode":38,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Michael G. Oefelein Clinical Trials","Bakersfield","California","93301",{"type":40,"coordinates":62},[63,64],-119.01871,35.37329,{"lat":64,"lon":63},[67,71],{"name":68,"role":24,"phone":69,"phoneExt":7,"email":70},"Evelyn De La Cruz","661-310-1063","edelacruz@droefelein.com",{"name":72,"role":55,"phone":7,"phoneExt":7,"email":7},"Michael G Oefelein, MD",{"facility":74,"status":33,"city":75,"state":59,"zip":76,"country":37,"countryCode":38,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"University of Southern California \u002F Norris Comprehensive Cancer Center","Los Angeles","90033",{"type":40,"coordinates":78},[79,80],-118.24368,34.05223,{"lat":80,"lon":79},[83,86],{"name":84,"role":24,"phone":48,"phoneExt":7,"email":85},"Christian Gonzalez-Gomez","Christian.GonzalezGomez@med.usc.edu",{"name":87,"role":55,"phone":7,"phoneExt":7,"email":7},"Anne Schuckman, MD",{"facility":89,"status":33,"city":90,"state":59,"zip":91,"country":37,"countryCode":38,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"McR, Llc.","Murrieta","92563",{"type":40,"coordinates":93},[94,95],-117.21392,33.55391,{"lat":95,"lon":94},[98,102],{"name":99,"role":24,"phone":100,"phoneExt":7,"email":101},"Laura Guerrero","951-677-3000","Laura.guerrero@folioclinicalresearch.com",{"name":103,"role":55,"phone":7,"phoneExt":7,"email":7},"Madhumitha Reddy, DO",{"facility":105,"status":33,"city":106,"state":107,"zip":108,"country":37,"countryCode":38,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"MedStar Washington Hospital Center","Washington D.C.","District of Columbia","20010",{"type":40,"coordinates":110},[111,112],-77.03637,38.89511,{"lat":112,"lon":111},[115,118],{"name":116,"role":24,"phone":7,"phoneExt":7,"email":117},"Win Phyu","win.phyu@medstar.net",{"name":119,"role":55,"phone":7,"phoneExt":7,"email":7},"Lambros Stamatakis, MD",{"facility":121,"status":33,"city":122,"state":123,"zip":124,"country":37,"countryCode":38,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"Advanced Urology Institute","Daytona Beach","Florida","32114",{"type":40,"coordinates":126},[127,128],-81.02283,29.21081,{"lat":128,"lon":127},[131,134],{"name":132,"role":24,"phone":7,"phoneExt":7,"email":133},"Seema Waris","seema.waris@auihealth.com",{"name":135,"role":55,"phone":7,"phoneExt":7,"email":7},"Samuel Lawindy",{"facility":137,"status":33,"city":138,"state":123,"zip":139,"country":37,"countryCode":38,"cosmosGeoPoint":140,"geoPoint":144,"contacts":145},"Lakeland Regional Medical Center - Hollis Cancer Center","Lakeland","33805",{"type":40,"coordinates":141},[142,143],-81.9498,28.03947,{"lat":143,"lon":142},[146,149,152],{"name":147,"role":24,"phone":7,"phoneExt":7,"email":148},"Brittany Collins","brittany.collins@mylrh.org",{"name":150,"role":24,"phone":7,"phoneExt":7,"email":151},"Dana Crowder","Dana.Crowder@myLRH.org",{"name":153,"role":55,"phone":7,"phoneExt":7,"email":7},"Peter Hinds, MD",{"facility":121,"status":33,"city":155,"state":123,"zip":156,"country":37,"countryCode":38,"cosmosGeoPoint":157,"geoPoint":161,"contacts":162},"Largo","33771",{"type":40,"coordinates":158},[159,160],-82.78842,27.90979,{"lat":160,"lon":159},[163,166],{"name":164,"role":24,"phone":7,"phoneExt":7,"email":165},"Amy Franklin","amy.franklin@auihealth.com",{"name":167,"role":55,"phone":7,"phoneExt":7,"email":7},"Matthew Truesdale, MD",{"facility":169,"status":33,"city":170,"state":171,"zip":172,"country":37,"countryCode":38,"cosmosGeoPoint":173,"geoPoint":177,"contacts":178},"Emory University","Atlanta","Georgia","30322",{"type":40,"coordinates":174},[175,176],-84.38798,33.749,{"lat":176,"lon":175},[179,183],{"name":180,"role":24,"phone":7,"phoneExt":181,"email":182},"Karol Cain","404-778-4162","Karol.cain@emory.edu",{"name":184,"role":55,"phone":7,"phoneExt":7,"email":7},"Vikram Narayan, MD",{"facility":186,"status":33,"city":187,"state":188,"zip":189,"country":37,"countryCode":38,"cosmosGeoPoint":190,"geoPoint":194,"contacts":195},"Uropartners c\u002Fo Associated Urological Specialists","Chicago Ridge","Illinois","60415",{"type":40,"coordinates":191},[192,193],-87.77922,41.70142,{"lat":193,"lon":192},[196,199],{"name":197,"role":24,"phone":7,"phoneExt":7,"email":198},"Kevia Semmes","k.semmes@auspecialists.com",{"name":200,"role":55,"phone":7,"phoneExt":7,"email":7},"Aaron D. Berger, MD",{"facility":202,"status":33,"city":203,"state":188,"zip":204,"country":37,"countryCode":38,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"UroPartners, LLC","Glenview","60026",{"type":40,"coordinates":206},[207,208],-87.78784,42.06975,{"lat":208,"lon":207},[211,214],{"name":212,"role":24,"phone":7,"phoneExt":7,"email":213},"Karolina Webb","kwebb@uropartners.com",{"name":215,"role":55,"phone":7,"phoneExt":7,"email":7},"Jeffrey Pearl, MD",{"facility":217,"status":33,"city":218,"state":219,"zip":220,"country":37,"countryCode":38,"cosmosGeoPoint":221,"geoPoint":225,"contacts":226},"Urologic Specialists of Northwest Indiana","Merrillville","Indiana","46410",{"type":40,"coordinates":222},[223,224],-87.33281,41.48281,{"lat":224,"lon":223},[227,230],{"name":228,"role":24,"phone":7,"phoneExt":7,"email":229},"Shawna Clemons","sclemons@urologic-specialists.com",{"name":231,"role":55,"phone":7,"phoneExt":7,"email":7},"Manoj Rao",{"facility":233,"status":33,"city":234,"state":235,"zip":236,"country":37,"countryCode":38,"cosmosGeoPoint":237,"geoPoint":241,"contacts":242},"Urology Center of Iowa Research","Clive","Iowa","50325",{"type":40,"coordinates":238},[239,240],-93.72411,41.60304,{"lat":240,"lon":239},[243,246],{"name":244,"role":24,"phone":7,"phoneExt":7,"email":245},"Danielle Hahn","Danielle.hahn@objective.health",{"name":247,"role":55,"phone":7,"phoneExt":7,"email":7},"Brian L. Gallagher, MD",{"facility":249,"status":33,"city":250,"state":251,"zip":252,"country":37,"countryCode":38,"cosmosGeoPoint":253,"geoPoint":257,"contacts":258},"Brigham and Women's Hospital","Boston","Massachusetts","02115",{"type":40,"coordinates":254},[255,256],-71.05977,42.35843,{"lat":256,"lon":255},[259,262],{"name":260,"role":24,"phone":7,"phoneExt":7,"email":261},"Ramona Faris","rfaris1@bwh.harvard.edu",{"name":263,"role":55,"phone":7,"phoneExt":7,"email":7},"Mark Preston, MD",{"facility":265,"status":33,"city":266,"state":267,"zip":268,"country":37,"countryCode":38,"cosmosGeoPoint":269,"geoPoint":273,"contacts":274},"Michigan Institute of Urology, PC","Troy","Michigan","40484",{"type":40,"coordinates":270},[271,272],-83.14993,42.60559,{"lat":272,"lon":271},[275,278],{"name":276,"role":24,"phone":7,"phoneExt":7,"email":277},"Danielle Osterhout","osterhoutd@michiganurology.com",{"name":279,"role":55,"phone":7,"phoneExt":7,"email":7},"Jason Hafron",{"facility":281,"status":33,"city":282,"state":283,"zip":284,"country":37,"countryCode":38,"cosmosGeoPoint":285,"geoPoint":289,"contacts":290},"Mayo Clinic Rochester","Rochester","Minnesota","55905",{"type":40,"coordinates":286},[287,288],-92.4699,44.02163,{"lat":288,"lon":287},[291,294],{"name":292,"role":24,"phone":7,"phoneExt":7,"email":293},"Kathyrn Barthels","barthels.kathryn@mayo.edu",{"name":295,"role":55,"phone":7,"phoneExt":7,"email":7},"Paras Shah, MD",{"facility":297,"status":33,"city":298,"state":299,"zip":300,"country":37,"countryCode":38,"cosmosGeoPoint":301,"geoPoint":305,"contacts":306},"The Urology Group, P.C.","Southaven","Mississippi","38671",{"type":40,"coordinates":302},[303,304],-90.01259,34.98898,{"lat":304,"lon":303},[307,310],{"name":308,"role":24,"phone":7,"phoneExt":7,"email":309},"Heer Patel","hpatel@memphisurology.com",{"name":311,"role":55,"phone":7,"phoneExt":7,"email":7},"Mark Greenberger",{"facility":313,"status":33,"city":314,"state":314,"zip":315,"country":37,"countryCode":38,"cosmosGeoPoint":316,"geoPoint":320,"contacts":321},"Integrated Medical Professionals, PLLC","New York","10016",{"type":40,"coordinates":317},[318,319],-74.00597,40.71427,{"lat":319,"lon":318},[322,325],{"name":323,"role":24,"phone":7,"phoneExt":7,"email":324},"Michael Yang","myang@imppllc.com",{"name":326,"role":55,"phone":7,"phoneExt":7,"email":7},"Jed Kaminetsky, MD",{"facility":328,"status":33,"city":329,"state":330,"zip":331,"country":37,"countryCode":38,"cosmosGeoPoint":332,"geoPoint":336,"contacts":337},"MidLantic Urology","Bala-Cynwyd","Pennsylvania","19004",{"type":40,"coordinates":333},[334,335],-75.23407,40.00761,{"lat":335,"lon":334},[338,341],{"name":339,"role":24,"phone":7,"phoneExt":7,"email":340},"Ashley Dziados","adziados@midlanticurology.com",{"name":342,"role":55,"phone":7,"phoneExt":7,"email":7},"Laurence Belkoff, DO",{"facility":344,"status":33,"city":345,"state":346,"zip":347,"country":37,"countryCode":38,"cosmosGeoPoint":348,"geoPoint":352,"contacts":353},"Lowcountry Urology Clinics, PA","North Charleston","South Carolina","29406",{"type":40,"coordinates":349},[350,351],-79.97481,32.85462,{"lat":351,"lon":350},[354,357],{"name":355,"role":24,"phone":7,"phoneExt":7,"email":356},"Samara Grimes","sgrimes@lcurology.com",{"name":358,"role":55,"phone":7,"phoneExt":7,"email":7},"Justin Ellett",{"facility":360,"status":33,"city":361,"state":362,"zip":363,"country":37,"countryCode":38,"cosmosGeoPoint":364,"geoPoint":368,"contacts":369},"Urology Partners of North Texas Research Institute","Arlington","Texas","76017",{"type":40,"coordinates":365},[366,367],-97.10807,32.73569,{"lat":367,"lon":366},[370,373,376],{"name":371,"role":24,"phone":7,"phoneExt":7,"email":372},"Grace Yoon","grace.yoon@objective.health",{"name":374,"role":24,"phone":7,"phoneExt":7,"email":375},"Cecillia Diaz","cecillia.diaz@objective.health",{"name":377,"role":55,"phone":7,"phoneExt":7,"email":7},"Michael P. Collini, MD",{"facility":379,"status":33,"city":380,"state":362,"zip":381,"country":37,"countryCode":38,"cosmosGeoPoint":382,"geoPoint":386,"contacts":387},"Urology Clinics of North Texas","Dallas","75231",{"type":40,"coordinates":383},[384,385],-96.80667,32.78306,{"lat":385,"lon":384},[388,391],{"name":389,"role":24,"phone":7,"phoneExt":7,"email":390},"Alexia Demitsas","ademitsas@urologyclinics.com",{"name":392,"role":55,"phone":7,"phoneExt":7,"email":7},"Jacob Taylor, MD",{"facility":394,"status":33,"city":395,"state":362,"zip":396,"country":37,"countryCode":38,"cosmosGeoPoint":397,"geoPoint":401,"contacts":402},"Urology San Antonio, PA dba USA Clinical Trials","San Antonio","78229",{"type":40,"coordinates":398},[399,400],-98.49363,29.42412,{"lat":400,"lon":399},[403,406,409],{"name":404,"role":24,"phone":7,"phoneExt":7,"email":405},"Trinifer Rosario","trinifer.rosario@usa-clinicaltrials.com",{"name":407,"role":24,"phone":7,"phoneExt":7,"email":408},"Valerie Strickland","valerie.strickland@usa-clinicaltrials.com",{"name":410,"role":55,"phone":7,"phoneExt":7,"email":7},"Daniel Zainfeld, MD",{"facility":412,"status":33,"city":413,"state":362,"zip":414,"country":37,"countryCode":38,"cosmosGeoPoint":415,"geoPoint":419,"contacts":420},"Digestive Health Research of North Texas","Wichita Falls","76301",{"type":40,"coordinates":416},[417,418],-98.49339,33.91371,{"lat":418,"lon":417},[421,424],{"name":422,"role":24,"phone":7,"phoneExt":7,"email":423},"Rebekah Milligan","rebekah.milligan@objective.health",{"name":425,"role":55,"phone":7,"phoneExt":7,"email":7},"Katherine E. Dowd, MD",{"facility":427,"status":33,"city":428,"state":429,"zip":430,"country":37,"countryCode":38,"cosmosGeoPoint":431,"geoPoint":435,"contacts":436},"University of Washington Medical Center","Seattle","Washington","98195",{"type":40,"coordinates":432},[433,434],-122.33207,47.60621,{"lat":434,"lon":433},[437,440],{"name":438,"role":24,"phone":48,"phoneExt":7,"email":439},"Casey Li","cyl14@uw.edu",{"name":441,"role":55,"phone":7,"phoneExt":7,"email":7},"Sarah Psutka, MD",{"facility":443,"status":33,"city":444,"state":429,"zip":445,"country":37,"countryCode":38,"cosmosGeoPoint":446,"geoPoint":450,"contacts":451},"Spokane Urology","Spokane","99202",{"type":40,"coordinates":447},[448,449],-117.42908,47.65966,{"lat":449,"lon":448},[452,457],{"name":453,"role":24,"phone":454,"phoneExt":455,"email":456},"Amy Bardwell","509-747-3147","112","amyb@spokaneurology.com",{"name":458,"role":55,"phone":7,"phoneExt":7,"email":7},"Shane Pearce, MD",{"type":460,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100550197","an-expanded-access-program-of-cretostimogene-grenadenorepvec-for-treatment-of-nmibc-for-patients-unresponsive-to-bcg-100550197",false,"NCT06443944","An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG","An Expanded Access Program of Cretostimogene Grenadenorepvec in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG)","Inclusion Criteria:\n\n1. Have pathologically confirmed BCG unresponsive CIS. There is no maximum limit to the amount of prior BCG treatment, but maintenance BCG should be administered on a schedule consistent with standard induction-maintenance protocols. Specifically, the definition of BCG unresponsive CIS will also require the following:\n\n   * Pathologically confirmed relapsed or persistent CIS (with or without HG Ta or HG T1 disease)\n   * Completion of qualifying BCG treatment (e.g., \"5+2\" minimum exposure) within 15 months of the initial qualifying dose of BCG.\n2. Have all Ta and\u002For T1 disease and all CIS resected or fulgurated, as feasible, prior to study treatment\n3. Ineligible to receive radical cystectomy (medically unfit) or refusal of radical cystectomy according to Investigator assessment.\n4. Acceptable baseline organ function\n\nExclusion Criteria:\n\n1. Muscle invasive bladder cancer, locally advanced or metastatic bladder cancer.\n2. Has had active autoimmune or inflammatory disease requiring systemic treatment within 4 weeks of Day 1. Replacement therapy is not considered an excluded form of systemic treatment and is allowed.\n3. Has received systemic anticancer therapy, including investigational agents, within 4 weeks of Day 1\n4. Is pregnant, currently breastfeeding or intending to breastfeed, beginning at Screening through 1 week after the last study treatment.","ALL","18 Years","EXPANDED_ACCESS","This is an open-label, expanded access trial designed to provide access to cretostimogene in patients with NMIBC (specifically CIS with or without HG Ta\u002FT1) unresponsive to BCG.",[473,474,475,476],"Non-Muscle Invasive Bladder Cancer","Urothelial Carcinoma","Urologic Cancer","Bladder Cancer",[478,476,479,11],"Urology","Non Muscle Invasive Bladder Cancer","2026-04-13",{"date":482,"type":483},"2026-04-14","ACTUAL",{"name":5,"class":6},26]