[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497598":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":8,"collaborators":7,"id":12,"slug":13,"hasResults":14,"nctId":15,"briefTitle":16,"officialTitle":17,"acronym":7,"eligibilityCriteria":18,"healthyVolunteers":14,"sex":19,"minAge":20,"maxAge":21,"enrollmentInfo":22,"targetDuration":7,"studyType":25,"phases":7,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":32,"whyStopped":7,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":7},{"fullName":5,"class":6},"Guangzhou Institute of Respiratory Disease","OTHER",null,{"type":9,"investigatorFullName":10,"investigatorTitle":11,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Jun Liu","GuangzhouIRD","100497598","an-exploratory-study-of-ctdna-mrd-in-predicting-the-efficacy-of-esophageal-squamous-cell-carcinoma-100497598",false,"NCT05759325","An Exploratory Study of ctDNA-MRD in Predicting the Efficacy of Esophageal Squamous Cell Carcinoma","Application of ctDNA-MRD in the Prediction of Curative Effect, Recurrence Monitoring and Prognosis Evaluation of Esophageal Squamous Cell Carcinoma (ESCC) During Perioperative Treatment","Inclusion Criteria:\n\n1. Patients with stage II-IVA Esophageal squamous cell carcinoma confirmed by clinical pathological staging;\n2. ≥18 years;\n3. Eastern Cooperative Oncology Group performance status score (ECOG PS) is 0 \\~ 1 points;\n4. Expected survival time ≥ 6 months;\n5. Patients agree and have the ability to follow the planned study visits, laboratory tests and other research steps.\n\nExclusion Criteria:\n\n1. Patients with other malignant tumors;\n2. Patient had undergone surgery before admission;\n3. Pregnant or lactating women;\n4. Patients with other serious diseases;\n5. Patients who could not understand the experiment content and could not cooperate with them and refused to sign the informed consent form;\n6. Patients with contraindications to radiotherapy and chemotherapy;\n7. Other researchers think it is not suitable.","ALL","18 Years","80 Years",{"count":23,"type":24},100,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to observe and evaluate the correlation between ctDNA-MRD and the therapeutic effect and prognosis of stage II-IVA operable esophageal squamous cell carcinoma.",[28],"Squamous Cell Carcinoma of Esophagus",[30,31],"ESCC","ctDNA","NOT_YET_RECRUITING","2023-02-25",{"date":35,"type":36},"2023-03-08","ACTUAL",{"date":38,"type":24},"2023-03",{"date":40,"type":24},"2026-12",{"name":5,"class":6}]