[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100423664":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":59,"collaborators":38,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":38,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":38,"enrollmentInfo":70,"targetDuration":38,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":38,"overallStatus":43,"whyStopped":38,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Diagnostic (IVIM DWI)","EXPERIMENTAL","Patients undergo IVIM DWI over 10 minutes during standard of care MRI within 30 days of starting chemotherapy and after 4-6 cycles of preoperative chemotherapy.",[13],"Procedure: Diffusion Weighted Imaging",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Diffusion Weighted Imaging","Undergo IVIM DWI",[9],[21,22,23,24,25,26,27,28,29],"Diffusion Weighted MRI","Diffusion-Weighted Magnetic Resonance Imaging","Diffusion-Weighted MR Imaging","Diffusion-Weighted MRI","DW-MRI","DWI","DWI MRI","DWI-MRI","MR Diffusion-Weighted Imaging",[31],{"name":32,"affiliation":5,"role":33},"Priya R Bhosale","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":38,"email":39},"CONTACT","713-792-0221",null,"priya.bhosale@mdanderson.org",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"M D Anderson Cancer Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-95.36327,29.76328,{"lat":53,"lon":52},[56,58],{"name":57,"role":36,"phone":37,"phoneExt":38,"email":38},"Priya R. Bhosale",{"name":57,"role":33,"phone":38,"phoneExt":38,"email":38},{"type":60,"investigatorFullName":38,"investigatorTitle":38,"investigatorAffiliation":38,"oldNameTitle":38,"oldOrganization":38},"SPONSOR","100423664","an-investigational-scan-intravoxel-incoherent-motion-diffusion-weighted-imaging-for-the-evaluation-of-colorectal-cancer-liver-metastases-treatment-response-100423664",false,"NCT04796818","An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response","Evaluation of Treatment Response of Colorectal Cancer Liver Metastases With Intravoxel Incoherent Motion Diffusion Weighted Imaging","Inclusion Criteria:\n\n* Patients with treatment-naive resectable CLM, who will start chemotherapy with oxaliplatin with fluorouracil (5-FU)\u002Fleucovorin (FOLFOX), irinotecan with 5-FU\u002Fleucovorin (FOLFIRI), or a combination, such as fluorouracil, leucovorin, oxaliplatin and irinotecan (FOLFOXIRI), with or without a biologic agent\n* Patients with at least 1 colorectal liver metastasis measuring at least 1 cm\n* Patients with anticipated follow-up before and after surgery at MD Anderson\n\nExclusion Criteria:\n\n* Patients who have already received preoperative chemotherapy for the CLM or will undergo radiation therapy, ablative therapies, or other non-surgical therapies directed at the liver\n* Patients allergic to gadolinium\n* Patients with pacemakers\n* Greater than 400 pounds in weight","ALL","18 Years",{"count":71,"type":72},70,"ESTIMATED","INTERVENTIONAL",[75],"NA","This trial evaluates the treatment response of colorectal cancer that has spread to the liver (liver metastases) using intravoxel incoherent motion diffusion weighted imaging (IVIM DWI). IVIM DWI is new kind of imaging scan that may help measure changes in disease before and after chemotherapy in patients with colorectal liver metastases.",[78,79,80,81,82,83,84],"Metastatic Colorectal Carcinoma","Metastatic Malignant Neoplasm in the Liver","Resectable Colorectal Carcinoma","Stage IV Colorectal Cancer AJCC v8","Stage IVA Colorectal Cancer AJCC v8","Stage IVB Colorectal Cancer AJCC v8","Stage IVC Colorectal Cancer AJCC v8","2026-01-12",{"date":87,"type":88},"2026-01-14","ACTUAL",{"date":90,"type":88},"2020-08-12",{"date":92,"type":72},"2026-01-31",{"name":5,"class":6},1]