[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635617":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":11,"responsibleParty":30,"collaborators":11,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":11,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":11,"enrollmentInfo":42,"targetDuration":11,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":61,"whyStopped":11,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":11},{"fullName":5,"class":6},"Texas Woman's University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Nurse-Led Virtual Purpose-Building Intervention","EXPERIMENTAL",null,[13],"Behavioral: Nurse-Led Purpose-Building Intervention",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"BEHAVIORAL","Nurse-Led Purpose-Building Intervention","The Nurse-Led Virtual Purpose-Building Intervention is a six-week, synchronous behavioral program delivered in small groups through a secure videoconferencing platform. Sessions are facilitated by a registered nurse trained in the study protocol. Each weekly session lasts 60 minutes and follows a standardized structure that includes: (1) an opening reflective prompt or grounding exercise, (2) guided group dialogue focused on meaning, identity, and purpose in the context of living with Multiple Sclerosis, (3) a brief integrative activity such as journaling or values-based reflection, and (4) a closing synthesis. The intervention emphasizes person-centered exploration, reflective engagement, and meaning-making rather than clinical counseling or symptom management. No medical treatments, diagnostic procedures, or therapeutic techniques are used. Fidelity to session structure is supported through a facilitator manual and weekly documentation.",[9],[21],{"name":22,"affiliation":5,"role":23},"Chanam Shin, PhD","STUDY_CHAIR",[25],{"name":26,"role":27,"phone":28,"phoneExt":11,"email":29},"Lisa Kelly","CONTACT","254-368-7638","lkelly5@twu.edu",{"type":31,"investigatorFullName":26,"investigatorTitle":32,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100635617","an-online-nurse-led-purpose-focused-group-program-for-adult-women-with-multiple-sclerosis-effects-on-meaning-and-quality-of-life-100635617",false,"NCT07555015","An Online Nurse-Led Purpose-Focused Group Program for Adult Women With Multiple Sclerosis: Effects on Meaning and Quality of Life","The Impact of a Nurse-Led Virtual Group Intervention on Purpose and Quality of Life in Adult Women With Multiple Sclerosis","Inclusion Criteria:\n\n* women\n* over the age of 18\n* a diagnosis of Multiple Sclerosis (Primary Progressive, Relapsing-Remitting, Secondary Progressive)\n* access to a device with internet capability as well as audio and video functions\n* comfortable reading, writing, and participating in group discussions in English\n\nExclusion Criteria:\n\n* currently enrolled (or have been enrolled within the last 4 weeks) of any similar group based intervention therapy (logotherapy, Acceptance and Commitment Therapy, or Cognitive Behavioral Therapy)","FEMALE","18 Years",{"count":43,"type":44},40,"ESTIMATED","INTERVENTIONAL",[47],"NA","The goal of this study is to learn how a six-week, nurse-led virtual group program may affect meaning in life and quality of life in adult women living with Multiple Sclerosis (MS). Many people with MS describe changes in identity, purpose, and daily life. This study will help researchers understand whether a structured group program can support women as they explore meaning and purpose while living with MS.\n\nThe main questions this study aims to answer are:\n\n* How does the program affect how participants search for meaning in life?\n* How does it affect their sense of life purpose or direction?\n* How does it affect their overall quality of life?\n\nThis study uses a single-group design. All participants will take part in the six-week virtual group program. The program is led by a registered nurse and focuses on guided reflection, values exploration, and group discussion.\n\nParticipants will:\n\n* Attend one virtual group session each week for six weeks\n* Take part in guided discussions and reflection exercises\n* Complete three online surveys: one before the program begins, one at Week 3, and one after Week 6\n* Use a computer, tablet, or phone to join all virtual sessions\n\nThe surveys will ask about:\n\n* How participants search for meaning in their lives\n* How much purpose and direction they feel\n* Their physical and emotional quality of life\n\nThere are no medications, invasive procedures, or in-person visits in this study.",[50],"Multiple Sclerosis",[50,52,53,54,55,56,57,58,59,60],"Quality of Life","Meaning in Life","Nurse-led behavioral intervention","Purpose-building intervention","Meaning-centered intervention","virtual group intervention","Nurse-guided","Psychological adaptations","Purpose in life","NOT_YET_RECRUITING","2026-04-27",{"date":64,"type":65},"2026-05-01","ACTUAL",{"date":67,"type":44},"2026-06",{"date":69,"type":44},"2026-09",{"name":5,"class":6}]