[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100461964":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":43,"responsibleParty":60,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":25,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Jagiellonian University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active repetitive transcranial magnetic stimulation","EXPERIMENTAL","10 hertz (Hz) rTMS will be administered over the primary motor area. Therapy will include 6 sessions (three sessions in two consecutive days). In every sessions 1500 magnetic pulses of 90% of the resting motor threshold intensity will be elicited.",[13],"Device: Active repetitive transcranial magnetic stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham repetitive transcranial magnetic stimulation","SHAM_COMPARATOR","Sham stimulation will mimic the active one except that the stimulating coil will be held perpendicularly to the scalp, which assures similar impression as the active stimulation but prevents that significant magnetic field will reach brain tissue.",[19],"Device: Sham repetitive transcranial magnetic stimulation",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","High frequency rTMS over the primary motor area to induce the long term potentiation of primary motor areas for the muscles of upper extremity.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Sham stimulation to mimic the high frequency rTMS over the primary motor area.",[15],[30],{"name":31,"affiliation":5,"role":32},"Tomasz Klupa, Professor","STUDY_CHAIR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Jakub M Antczak, MD","CONTACT","+48 795 421 153","jakub.antczak@uj.edu.pl",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":42},"Gabriela G Rusin, MD","+48 601 661 607","gabriela.rusin@doctoral.uj.edu.pl",[44],{"facility":45,"status":46,"city":47,"state":25,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Jagiellonian University Medical College","RECRUITING","Krakow","31008","Poland","PL",{"type":52,"coordinates":53},"Point",[54,55],19.93658,50.06143,{"lat":55,"lon":54},[58],{"name":59,"role":36,"phone":25,"phoneExt":25,"email":38},"Jakub Antczak, MD",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Jakub Antczak","Principal Investigator","100461964","analgesic-effect-of-accelerated-repetitive-transcranial-magnetic-stimulation-in-neuropathic-pain-100461964",false,"NCT05295498","Analgesic Effect of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropathic Pain","Analgesic Effect of Accelerated Repetitive Transcranial Magnetic Stimulation in Pain Related to Peripheral Neuropathy","Inclusion Criteria:\n\n* Diagnosis of peripheral neuropathy\n* Neuropathic pain of constant severity since not less than a month and requiring use of analgesics more than once a week\n* Score of 30 millimeter or more on the 100 millimeter visual analog scale of pain intensity at inclusion\n\nExclusion Criteria:\n\n* Severe depression\n* Personality disorders and other psychiatric conditions, which could disturb the participation in the study\n* Cognitive deficits, which could disturb the participation in the study\n* Epilepsy\n* Presence of magnetic material in the reach of magnetic field\n* Pregnancy\n* Likelihood to get pregnant\n* Intracranial electrodes","ALL","18 Years",{"count":74,"type":75},70,"ESTIMATED","INTERVENTIONAL",[78],"NA","Peripheral neuropathy is a frequent condition, commonly associated with pain. Repetitive Transcranial Magnetic Stimulation (rTMS) is a noninvasive method of modulation of brain plasticity and is regarded as one of alternative methods to alleviate pain associated with various kind of neuropathies. rTMS is usually performed once a day and the whole therapy of neuropathic pain lasts one week. In a number of recent clinical trials including patients with depression and some other disorders, rTMS was delivered several times a day, which reduced the time of the whole therapy. This approach was termed an accelerated rTMS. The purpose of this study is to investigate feasibility of accelerated rTMS in treatment of neuropathic pain.",[81],"Peripheral Neuropathy",[83,84,85,86],"Peripheral neuropathy","Neuropathic pain","rTMS","analgesic effect","2024-10-09",{"date":89,"type":90},"2024-10-10","ACTUAL",{"date":92,"type":90},"2022-11-04",{"date":94,"type":75},"2026-09-30",{"name":62,"class":6},1]