[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561018":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":39,"locations":45,"responsibleParty":69,"collaborators":31,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":31,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":31,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":31,"overallStatus":47,"whyStopped":31,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Transversus abdominis plane group","EXPERIMENTAL","patients will receive unilateral ultrasound-guided oblique subcostal transversus abdominis plane block block",[13],"Drug: Transversus abdominis plane block",{"label":15,"type":10,"description":16,"interventionNames":17},"External oblique intercostal group","Patients will receive unilateral ultrasound-guided external oblique intercostal block",[18],"Drug: External Oblique Intercostal Plane Block",{"label":20,"type":21,"description":22,"interventionNames":23},"Control group","ACTIVE_COMPARATOR","Patients will receive IV morphine 0.1mg\u002Fkg after induction of general anesthesia.",[24],"Drug: Control group",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Transversus abdominis plane block","Patients will receive transversus abdominis plane block with an oblique subcostal approach in the supine position. The anesthesiologist will place the linear ultrasound transducer obliquely on the upper abdominal wall along the subcostal margin near the xiphisternum of the sternum in the midline of the abdomen. The anesthesiologist will direct a 22G, 80 mm needle toward the transversus abdominis fascia and inject 25 mL of 0.25% bupivacaine between the rectus abdominis and transversus abdominis muscles along the subcostal line.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"External Oblique Intercostal Plane Block","Patients will receive external oblique intercostal block the patient will be in the supine position with their ipsilateral arm abducted, A linear ultrasound transducer will be placed in the sagittal plane between the midclavicular and anterior axillary lines at the level of sixth rib, with the orientation marker directed cranially. The skin will be sterilized, and the probe will be placed over the sixth rib medial to the anterior axillary line in a parasagittal orientation the in-plane technique with a 22G, 80 mm block needle will be used to inject 25 ml of 0.25% bupivacaine into the external oblique intercostal plane.",[15],{"type":27,"name":20,"description":37,"armGroupLabels":38,"otherNames":31},"Patients will receive IV morphine 0.1mg\u002Fkg after induction of general anesthesia.\n\nGeneral anesthesia induction will be performed with fentanyl 1-2 μg\u002Fkg, propofol 2-3 mg\u002Fkg, and rocuronium 0.6 mg\u002Fkg and maintained with sevoflurane.",[20],[40],{"name":41,"role":42,"phone":43,"phoneExt":31,"email":44},"Ahmed A Abdelbaset, Master","CONTACT","00201144329865","ahmedabdelbaset500@gmail.com",[46],{"facility":5,"status":47,"city":48,"state":31,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Cairo","11796","Egypt","EG",{"type":53,"coordinates":54},"Point",[55,56],31.24967,30.06263,{"lat":56,"lon":55},[59,60,63,65,67],{"name":41,"role":42,"phone":43,"phoneExt":31,"email":44},{"name":61,"role":62,"phone":31,"phoneExt":31,"email":31},"Khaled Elsamahy, MD","SUB_INVESTIGATOR",{"name":64,"role":62,"phone":31,"phoneExt":31,"email":31},"Walaa Youssef, MD",{"name":66,"role":62,"phone":31,"phoneExt":31,"email":31},"Sayed M Abed, MD",{"name":68,"role":62,"phone":31,"phoneExt":31,"email":31},"Asmaa E Khalil, MD",{"type":70,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Ahmed Abdelbaset Mostafa","Specialist of Anesthesia, Surgical Intensive Care & Pain Relief","100561018","analgesic-efficacy-of-external-oblique-intercostal-block-vs-subcostal-transversus-abdominis-plane-block-in-open-surgical-nephrectomy-100561018",false,"NCT06584695","Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy","Analgesic Efficacy of External Oblique Intercostal Block Versus Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy","Inclusion Criteria:\n\n* Age (18-65) year.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) class II and III.\n* Cancer patients candidate for open nephrectomy .\n\nExclusion Criteria:\n\n* Patient refusal.\n* Skin lesions or infection at the site of proposed needle insertion.\n* Cognitive disorders.\n* History of psychiatric disorders or drug abuse.\n* Patients allergic to medication used.\n* ASA class IV.\n* Coagulopathy.\n* Body mass index (BMI) more than 35.","ALL","18 Years","65 Years",{"count":84,"type":85},63,"ESTIMATED","INTERVENTIONAL",[88],"NA","To compare the efficacy of unilateral ultrasound-guided oblique subcostal transversus abdominis plane block with unilateral ultrasound-guided external oblique intercostal plane block in providing intraoperative and postoperative analgesia in cancer patients undergoing open nephrectomy.",[91,92,93,94,95],"Analgesic Efficacy","External Oblique Intercostal Block","Subcostal Transversus Abdominis Plane Block","Open","Nephrectomy","2024-09-05",{"date":98,"type":99},"2024-09-19","ACTUAL",{"date":96,"type":99},{"date":102,"type":85},"2025-12-01",{"name":5,"class":6},1]