[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597627":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":20,"locations":27,"responsibleParty":51,"collaborators":19,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":19,"enrollmentInfo":62,"targetDuration":19,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":19,"overallStatus":72,"whyStopped":19,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Institut du Cancer de Montpellier - Val d'Aurelle","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"COHORT 1 - CURE","Patients with histologically proven metastatic non-small cell lung carcinoma eligible for immunotherapy",[12],"Biological: Blood sampling C1",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"BIOLOGICAL","Blood sampling C1","Blood samples will be collected at four key time points :\n\n* baseline (T1),\n* first scan assessment (T2),\n* second scan assessment (T3),\n* and progression (T4).",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},"Emmanuelle TEXIER","CONTACT","467613102","+33","emmanuelle.texier@icm.unicancer.fr",[28],{"facility":29,"status":19,"city":30,"state":31,"zip":32,"country":31,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle","Montpellier","France","34298","FR",{"type":35,"coordinates":36},"Point",[37,38],3.87635,43.61093,{"lat":38,"lon":37},[41,45,48],{"name":42,"role":23,"phone":43,"phoneExt":25,"email":44},"Marc Ychou, MD, PhD","467613066","marc.ychou@icm.unicancer.fr",{"name":46,"role":23,"phone":24,"phoneExt":25,"email":47},"Aurore MOUSSION","aurore.moussion@icm.unicancer.fr",{"name":49,"role":50,"phone":19,"phoneExt":19,"email":19},"William JACOT, MD","PRINCIPAL_INVESTIGATOR",{"type":52,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100597627","analysis-of-circulating-tumor-markers-in-blood---alcina-5-100597627",false,"NCT07060950","Analysis of Circulating Tumor Markers in Blood - ALCINA 5","ALCINA 5","Inclusion Criteria:\n\n1. Patient presenting an invasive tumoral pathology (proved or suspected), whatever is the location or the stage,\n2. 18 years old or higher ?\n3. Patient who has provided informed, written, and explicit consent,\n4. Patient affiliated with a French Social Protection System.\n\n   In the case of a tumor biopsy:\n5. Tumor considered as accessible by biopsy,\n6. Normal hemostasis assessment (PT, APTT, platelets),\n7. No anticoagulant or antiaggregant treatment for the biopsy.\n\nExclusion Criteria:\n\n1. Pregnant woman and\u002For breast-feeding,\n2. Patient whose regular follow-up is impossible for psychological, family, social or geographical reasons,\n3. Private persons of freedom or under guardianship,\n4. Patient with a history of other invasive cancers within the 5 years preceding inclusion.","ALL","18 Years",{"count":63,"type":64},620,"ESTIMATED","INTERVENTIONAL",[67],"NA","The circulating tumoral biomarkers in the blood are the object of numerous researches for several decades. The potential clinical interests of these circulating biomarkers are diagnostic, prognostic, predictive of the efficiency of targeted therapies (according to the mutational profile of the cancer), and could allow the study of the mechanisms of resistance under process. In the multiplicity of these blood potential biomarkers joins a permanent evolution of the technological means used to detect them\u002Fto quantify, as well as to estimate their clinical utility.",[70,71],"Cancer","Lung Cancer, Non-Small Cell","NOT_YET_RECRUITING","2025-09-18",{"date":75,"type":76},"2025-09-19","ACTUAL",{"date":78,"type":64},"2025-10",{"date":80,"type":64},"2035-07",{"name":5,"class":6},1]