[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626620":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":51,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":25,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":33,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Casa di Cura Dott. Pederzoli","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"combined exercise","EXPERIMENTAL","participants will undergo a combined endurance and resistance exercise training",[13],"Other: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"control group","ACTIVE_COMPARATOR","participants performs outcome measures sessions only, including blood sample collection.",[19],"Other: control",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Exercise","All participants will be involved in the exercise training three times per week for 24 weeks: endurance exercise training, resistant exercise training",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"control","outcome measures",[15],[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Ospedale P. Pederzoli Casa di Cura Privata S.p.A.","RECRUITING","Peschiera del Garda","Verona","37019","Italy","IT",{"type":40,"coordinates":41},"Point",[42,43],10.68614,45.43912,{"lat":43,"lon":42},[46],{"name":47,"role":48,"phone":49,"phoneExt":25,"email":50},"Yuri Battaglia, MD","CONTACT","+39 0456444193","urc@ospedalepederzoli.it",{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100626620","analysis-of-effects-of-high-intensity-physical-exercise-in-subjects-with-dialyzed-chronic-kidney-disease-and-in-conservative-treatment-100626620",false,"NCT07438002","Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment","Effect of Exercise in Patients With Chronic Kidney Disease: TONE Trial","TONE","Inclusion Criteria:\n\n* Signature of the informed consent\n* Patients with CKD stage 1 to 5 under conservative treatment\n* Patients undergoing chronic hemodialysis for at least 3 months\n* Age ≥ 18\n\nExclusion Criteria:\n\n* Severe cardiovascular disease (NYHA class IV or hypertension class III)\n* TIA or myocardial ischemia within the last three months\n* Anatomical limitations\n* Health conditions detected during the stress test (CPET)","ALL","18 Years",{"count":64,"type":65},50,"ESTIMATED","INTERVENTIONAL",[68],"NA","This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group",[71],"Chronic Kidney Disease",[73,74,75],"Nephrology","exercise","physical activity","2026-02-20",{"date":78,"type":79},"2026-02-27","ACTUAL",{"date":81,"type":79},"2025-09-02",{"date":83,"type":65},"2026-09",{"name":5,"class":6},1]