[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624986":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":31,"responsibleParty":52,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":10,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients undergoing abdominal surgery with intestinal anastomosis",null,"Older than 18 years of age",[13],"Other: Not applicable- observational study",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Not applicable- observational study","Fecal sample collection",[9],[20],{"name":21,"affiliation":22,"role":23},"Mariano García-Arranz, PhD","Health Research Institute Fundación Jiménez Díaz","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},"Héctor Guadalajara-Labajo, MD, PhD","CONTACT","+ 34 550 4800","4331","h.guadalajara@quironsalud.es",[32],{"facility":33,"status":34,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"University Hospital Fundación Jiménez Díaz","RECRUITING","Madrid","28040","Spain","ES",{"type":40,"coordinates":41},"Point",[42,43],-3.70256,40.4165,{"lat":43,"lon":42},[46,48],{"name":26,"role":27,"phone":47,"phoneExt":29,"email":30},"+34 915504800",{"name":21,"role":27,"phone":49,"phoneExt":50,"email":51},"+34 91 5504800","3398","mariano.garcia@iis-fjd.es",{"type":23,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mariano Garcia Arranz","Doctor of Biochemistry and Molecular Biology","100624986","analysis-of-the-composition-of-the-intestinal-microbiota-in-patients-post-intestinal-anastomosis-100624986",false,"NCT07416760","Analysis of the Composition of the Intestinal Microbiota in Patients Post-intestinal Anastomosis","Analysis of the Composition of the Intestinal Microbiota and Its Evolution in Patients Post-intestinal Anastomosis","MIDESIN","Inclusion Criteria:\n\n* Patients who have undergone colorectal intestinal anastomosis.\n* Signing of the informed consent form.\n* Age ≥18 years with good functional status.\n* Availability for postoperative follow-up.\n\nExclusion Criteria:\n\n* Emergency surgery.\n* Intra-abdominal sepsis or previous dehiscence.\n* Severe immunosuppression.\n* Use of antibiotics in the 3 months prior to preoperative preparation.\n* Pregnancy or breastfeeding.","ALL","18 Years",{"count":66,"type":67},30,"ESTIMATED","OBSERVATIONAL","Recent research suggests a significant link between gut microbiota and anastomotic leakage (AL) in colorectal surgery. Patients who develop AL have a higher abundance of bacteria from the Lachnospiraceae family and lower microbial diversity.\n\nConsidering the bibliographic data, our main interest is to analyze the microbial population of patients in our social environment and then look for differences in the microbiome between those who have suffered an anastomotic dehiscence (around 8-9% according to the results of our hospital's Surgery Department) and those who have not.",[71],"Abdominal Surgery",[73,74,75],"Microbiome","intestinal anastomosis","dehiscence","2026-02-13",{"date":78,"type":79},"2026-02-18","ACTUAL",{"date":81,"type":79},"2026-02-14",{"date":83,"type":67},"2026-12-14",{"name":5,"class":6},1]