[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496291":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":72,"collaborators":74,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":86,"maxAge":10,"enrollmentInfo":87,"targetDuration":10,"studyType":90,"phases":10,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Saint Etienne","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with FECD",null,"Patients with Fuchs Endothelial Corneal Dystrophy (FECD). They will have a collection of data and a blood sample",[13,14,15],"Genetic: Genotyping","Diagnostic Test: Histology","Other: Collection of data",[17,22,27],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"GENETIC","Genotyping","Genotyping will measure the triple nucleotide repeat in the TCF4 gene and search for other known mutations in other genes Blood sample will be performed (genetic analyses).",[9],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"DIAGNOSTIC_TEST","Histology","Histology will be performed on flat mounted Descemet membrane obtained after Descemetorhexis",[9],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"Collection of data","Collection of data of examination for diagnosis of the Fuchs Endothelial Corneal Dystrophy (FECD) including slit lamp results will be performed.",[9],[32],{"name":33,"affiliation":34,"role":35},"GILLES THURET, MD-PhD","CHU DE SAINT-ETIENNE","PRINCIPAL_INVESTIGATOR",[37,42],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","(0)477127793","+33","gilles.thuret@univ-st-etienne.fr",{"name":43,"role":38,"phone":44,"phoneExt":40,"email":45},"PHILIPPE GAIN, MD-PhD","0477127793","philippe.gain@chu-st-etienne.fr",[47],{"facility":48,"status":49,"city":50,"state":10,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"CHU Saint-Etienne","RECRUITING","Saint-Etienne","42055","France","FR",{"type":55,"coordinates":56},"Point",[57,58],4.39,45.43389,{"lat":58,"lon":57},[61,63,66,68,70],{"name":62,"role":35,"phone":10,"phoneExt":10,"email":10},"Gilles THURET, MD PhD",{"name":64,"role":65,"phone":10,"phoneExt":10,"email":10},"Marie-Caroline TRONE, MD","SUB_INVESTIGATOR",{"name":67,"role":65,"phone":10,"phoneExt":10,"email":10},"Philippe GAIN, MD PhD",{"name":69,"role":65,"phone":10,"phoneExt":10,"email":10},"Emera CHHUY, MD",{"name":71,"role":65,"phone":10,"phoneExt":10,"email":10},"Lise LANFANT, MD",{"type":73,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[75],{"name":76,"class":6},"Kyoto University, Graduate School of Medicine","100496291","analysis-of-the-genotypephenotype-relationship-in-the-fuchs-corneal-endothelial-dystrophy-in-france-100496291",false,"NCT05742321","Analysis of the Genotype\u002FPhenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France","Analysis of the Genotype\u002FPhenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France. The French Fuchs' Follow-up Study (Phase 2), F3S2","F3S2","Inclusion Criteria:\n\n* affiliated with or entitled to a social security scheme\n* Consent form to participate in the study signed\n* with an FECD certified by slit lamp examination\n* requiring an endothelial keratoplasty\n\nExclusion Criteria:\n\n\\- Patients under guardianship or curators","ALL","18 Years",{"count":88,"type":89},500,"ESTIMATED","OBSERVATIONAL","The pathophysiology of the most common corneal endothelial dystrophies (Fuchs' Corneal Endothelial Dystrophy, FECD) is beginning to be dismembered. There is a significant heterogeneity in the clinical forms and the investigators have just highlighted a great diversity of histological forms that seem to define distinct groups.",[93],"Corneal Dystrophies",[93,95,96],"Corneal Endothelial Dystrophy","Fuchs' Corneal Endothelial Dystrophy, FECD","2026-05-05",{"date":99,"type":100},"2026-05-06","ACTUAL",{"date":102,"type":100},"2024-08-08",{"date":104,"type":89},"2026-09-01",{"name":5,"class":6},1]