[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100448809":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":50,"collaborators":54,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"IRCCS San Raffaele","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute Myeloid Leukemia relapsed patients",null,"Adult patients (\\\u003C 18 years old), with Acute Myeloid Leukemia, who relapse after allogeneic transplantation from either family or unrelated donors, regardless of the cellular source of the transplant (bone marrow, mobilized peripheral stem cells or cord blood).",[13],"Other: Observations on Relapsed AML Allogeneic Transplanted patients",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Observations on Relapsed AML Allogeneic Transplanted patients","This is not an interventional clinical study. This is a retrospective\u002Fprospective observational study on Relapsed AML Allogenic Transplanted patients. Additional samples will be collected during the standard practice.",[9],[20],{"name":21,"affiliation":22,"role":23},"Fabio Ciceri, MD","IRCCS Ospedale San Raffaele","PRINCIPAL_INVESTIGATOR",[25,29],{"name":21,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","+39 02-2643-3093","ciceri.clinicaltrials@hsr.it",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Stefania Trinca","+39 02-2643-4289","regolatorio.scp@hsr.it",[34],{"facility":22,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Milan","Milano","20132","Italy","IT",{"type":42,"coordinates":43},"Point",[44,45],9.18951,45.46427,{"lat":45,"lon":44},[48,49],{"name":21,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Ciceri Fabio","Principal Investigator, Professor and Head of Hematology",[55,57],{"name":56,"class":6},"Gruppo Italiano Trapianto di Midollo Osseo",{"name":58,"class":6},"Associazione Italiana per la Ricerca sul Cancro","100448809","analysis-of-the-immunobiology-of-acute-myeloid-leukemia-relapses-after-allogeneic-hematopoietic-stem-cell-transplant-hsct-for-the-generation-of-guidelines-and-personalized-therapeutic-pathways-100448809",false,"NCT05124288","Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways","Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways","GITMO-RELAPSE","Inclusion Criteria:\n\n* Adult patients with Acute Myeloid Leukemia, who relapse after allogeneic transplantation from either family or unrelated donors, regardless of the cellular source of the transplant (bone marrow, mobilized peripheral stem cells or cord blood), who have signed the informed consent of the study;\n* For the coordinating center, all patients who have previously signed informed consent to the \"Hematological Neoplasms Biobank\" and for which samples, stored in the Biobank are available.\n* For the other centers, all patients who have previously signed an informed consent, aimed at the prior authorization for the storage of samples in the biobank of the aforementioned center, according to centers own practice, and for which samples, stored in a Biobank, are available.\n\nExclusion Criteria:\n\n* Participation in clinical protocols that expressly exclude the possibility of participating in other studies.","ALL","18 Years",{"count":70,"type":71},500,"ESTIMATED","OBSERVATIONAL","This is a retrospective and prospective non-interventional multicenter observational study. Neither diagnostic approaches nor experimental drugs\u002Fprocedure will be applied and the samples will take place at the same time as the samples will be taken during routinary clinical practice.\n\nThe aim of this study is to analyze the immunobiology of Acute Myeloid Leukemia (AML) relapses after allogeneic HSCT for the generation of guidelines and personalized therapeutic pathways.",[75],"Acute Myeloid Leukemia, in Relapse",[77,78,79,80],"Haematopoietic Stem Cell Transplantation","Graft versus Host Disease","Acute Myeloid Leukemia","Human Leukocyte Antigens loss","2025-05-07",{"date":83,"type":84},"2025-05-13","ACTUAL",{"date":86,"type":84},"2022-07-18",{"date":88,"type":71},"2027-06-20",{"name":52,"class":6},1]