[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100454469":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":34,"locations":42,"responsibleParty":90,"collaborators":92,"id":102,"slug":103,"hasResults":104,"nctId":105,"briefTitle":106,"officialTitle":106,"acronym":10,"eligibilityCriteria":107,"healthyVolunteers":108,"sex":109,"minAge":110,"maxAge":10,"enrollmentInfo":111,"targetDuration":10,"studyType":114,"phases":10,"briefSummary":115,"conditions":116,"keywords":10,"overallStatus":45,"whyStopped":10,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":128},{"fullName":5,"class":6},"Hugo W. Moser Research Institute at Kennedy Krieger, Inc.","OTHER",[8,12,15,20],{"label":9,"type":10,"description":11,"interventionNames":10},"Participants with CP (survey-only)",null,"Subjects in this group are age 8 and older with a diagnosis of cerebral palsy. Participants are either able to affirmatively consent or assent with LAR consent. This sample will have a CFCS score ranging between 1 and 3 and should be able to unambiguously respond to a 65 item multiple choice survey.",{"label":13,"type":10,"description":14,"interventionNames":10},"Neurotypical participants (survey-only)","Subjects in this group are age 8 and older with no clinically significant neurologic or developmental diagnosis. Participants are either able to affirmatively consent or assent with LAR consent.",{"label":16,"type":10,"description":17,"interventionNames":18},"Participants with CP (Survey + MRI)","Subjects are 8 years or older with a diagnosis of cerebral palsy and clinical imaging demonstrating isolated periventricular white matter injury. Clinical assessment states that neurologic symptoms are attributed to this isolated injury. Subjects in this group must be able to lie still in a scanner for 1.5 hours in at most 2 sessions and be able to have an MRI. Participants must be able to affirmatively consent or assent with LAR consent.",[19],"Diagnostic Test: MRI",{"label":21,"type":10,"description":22,"interventionNames":23},"Neurotypical participants (Survey + MRI)","Subjects in this group are age 8 and older with no clinically significant neurologic or developmental diagnosis. Participants are able to affirmatively consent and are able to have an MRI. Subjects also should be able to lie still in a scanner for 1.5 hours.",[19],[25],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"DIAGNOSTIC_TEST","MRI","Research unsedated MRI scans (outside of usual care) will be performed using a 3T Philips scanner at the F.M. Kirby Research Center. An MRI scanning protocol will be at the F.M. Kirby Research Center; the protocol will not last more than 1.5 hours. Acquisitions will include a triplanar survey, functional and anatomical multi-slice imaging of the brain as well as MRI of selected spinal levels. Protocols will be used that do not involve use of contrast agents and limit power\u002Ftissue absorption as well as otherwise remain within FDA and Kirby Center safety regulations. When possible, MRI will be performed within 3 months of initial survey\u002Finterview administration. If MRI is scheduled \\>3 months after initial survey\u002Finterview administration, a brief survey will be re-administered to screen for changes in pain\u002Fclinical status.",[21,16],[31],{"name":32,"affiliation":5,"role":33},"Eric Chin, MD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Paul Salib, MS","CONTACT","(443) 923-9272","CPpainStudy@kennedykrieger.org",{"name":32,"role":37,"phone":41,"phoneExt":10,"email":39},"(443) 923-9141",[43,60,71,82],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"F.M. Kirby Center","RECRUITING","Baltimore","Maryland","21205","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-76.61219,39.29038,{"lat":55,"lon":54},[58],{"name":32,"role":37,"phone":59,"phoneExt":10,"email":39},"443-923-9141",{"facility":61,"status":45,"city":46,"state":47,"zip":62,"country":49,"countryCode":50,"cosmosGeoPoint":63,"geoPoint":65,"contacts":66},"Mt. Washington Pediatric Hospital","21209",{"type":52,"coordinates":64},[54,55],{"lat":55,"lon":54},[67],{"name":68,"role":37,"phone":69,"phoneExt":10,"email":70},"Stephen Nichols, MD","410-578-8600","snichols@mwph.org",{"facility":72,"status":45,"city":46,"state":47,"zip":73,"country":49,"countryCode":50,"cosmosGeoPoint":74,"geoPoint":76,"contacts":77},"Johns Hopkins Hospital","21287",{"type":52,"coordinates":75},[54,55],{"lat":55,"lon":54},[78],{"name":79,"role":37,"phone":80,"phoneExt":10,"email":81},"Shenandoah Robinson, MD","667-208-9378","srobin81@jhmi.edu",{"facility":83,"status":45,"city":46,"state":47,"zip":73,"country":49,"countryCode":50,"cosmosGeoPoint":84,"geoPoint":86,"contacts":87},"Kennedy Krieger Institute",{"type":52,"coordinates":85},[54,55],{"lat":55,"lon":54},[88],{"name":32,"role":37,"phone":59,"phoneExt":10,"email":89},"chine@kennedykrieger.org",{"type":91,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[93,95,98,100],{"name":94,"class":6},"Johns Hopkins University",{"name":96,"class":97},"Mount Washington Pediatric Hospital","UNKNOWN",{"name":99,"class":97},"Neurosurgery Pain Research Institute",{"name":101,"class":6},"Cerebral Palsy Alliance","100454469","anatomical-and-functional-imaging-correlates-of-chronic-pain-in-cerebral-palsy-100454469",false,"NCT05197946","Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy","Participants with CP (Survey-only):\n\nInclusion Criteria:\n\n* Individual 8+ years of age\n* Diagnosis of cerebral palsy\n\nExclusion Criteria:\n\n-None\n\nNeurotypical participants: (Survey-only):\n\nInclusion Criteria:\n\n* Individual 8+ years of age\n* Adult subject able to indicate understanding and affirmative consent OR Adult\u002Fchild subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents\n\nExclusion Criteria:\n\n-Clinically-significant neurologic or developmental diagnosis\n\nParticipants with CP (Survey and MRI):\n\nInclusion Criteria:\n\n* Individual 8+ years of age\n* Adult subject able to indicate understanding and affirmative consent OR Adult subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents\n* Diagnosis of cerebral palsy\n* Clinical imaging demonstrating isolated periventricular white matter injury\n* Clinical judgment that all neurologic symptoms are attributable to non-progressive periventricular white matter injury\n* Able to lie still in scanner for 1.5 hours in at most 2 sessions and be able to have MRI\n\nExclusion Criteria:\n\n-None\n\nNeurotypical participants (Survey and MRI):\n\nInclusion Criteria:\n\n* Individual 8+ years of age\n* Adult subject able to indicate understanding and affirmative consent\n* Able to lie still in scanner for 1.5 hours and be able to have MRI\n\nExclusion Criteria:\n\n-Clinically-significant neurologic or developmental diagnosis",true,"ALL","8 Years",{"count":112,"type":113},300,"ESTIMATED","OBSERVATIONAL","The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.",[117,118],"Cerebral Palsy","Chronic Pain","2026-06-26",{"date":121,"type":122},"2026-06-29","ACTUAL",{"date":124,"type":122},"2018-12-04",{"date":126,"type":113},"2028-12",{"name":5,"class":6},4]