[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605904":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":26,"responsibleParty":52,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Istanbul Physical Medicine Rehabilitation Training and Research Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Knee Osteoarthritis Patients",null,"This cohort includes adult patients diagnosed with knee osteoarthritis who meet the inclusion criteria. All participants will undergo clinical evaluation of pain, functional status, quality of life, and kinesiophobia using validated scales (VAS, WOMAC, SF-36, TSK). Radiographic assessment will be performed on existing anteroposterior knee X-rays taken within the last 6 months, including femoro-tibial angle and joint space width measurements. No experimental intervention will be applied; data will be collected in an observational and cross-sectional manner.",[13],{"name":14,"affiliation":15,"role":16},"Selim Sezikli, MD","Istanbul Physical Medicine and Rehabilitation Training and Research Hospital","PRINCIPAL_INVESTIGATOR",[18,22],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","+90 506 510 18 33","selimsezikli@hotmail.com",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},"Cansın Medin Ceylan, Assoc. Prof.","+90 531 575 95 39","cansinmedin@gmail.com",[27],{"facility":15,"status":28,"city":29,"state":10,"zip":30,"country":31,"countryCode":10,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Istanbul","34186","Turkey (Türkiye)",{"type":33,"coordinates":34},"Point",[35,36],28.94966,41.01384,{"lat":36,"lon":35},[39,41,42,44,46,48,50],{"name":14,"role":19,"phone":40,"phoneExt":10,"email":21},"+90 (212) 496 50 00",{"name":14,"role":16,"phone":10,"phoneExt":10,"email":10},{"name":23,"role":43,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":45,"role":43,"phone":10,"phoneExt":10,"email":10},"Merve Damla Korkmaz, Assoc. Prof.",{"name":47,"role":43,"phone":10,"phoneExt":10,"email":10},"Yelda Soluk Ozdemir, MD",{"name":49,"role":43,"phone":10,"phoneExt":10,"email":10},"Canan Avcı, MD",{"name":51,"role":43,"phone":10,"phoneExt":10,"email":10},"Nazlı Derya Bugdaycı, Prof.",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Selim Sezikli","Medical Doctor, Specialist in Physical Medicine and Rehabilitation","100605904","anatomical-axis-on-x-ray-and-its-relationship-with-pain-and-kinesiophobia-in-knee-osteoarthritis-100605904",false,"NCT07168590","Anatomical Axis on X-Ray and Its Relationship With Pain and Kinesiophobia in Knee Osteoarthritis","The Effect of Radiographically Evaluated Anatomical Axis on Pain and Kinesiophobia in Knee Osteoarthritis","KOA-AXIS","Inclusion Criteria:\n\n* Diagnosis of knee osteoarthritis (clinical and radiographic)\n* Having an anteroposterior knee X-ray taken within the last 6 months\n* Voluntary agreement to participate in the study\n* Cognitive ability sufficient to understand test instructions\n\nExclusion Criteria:\n\n* History of knee surgery\n* Illiteracy (inability to read\u002Fwrite)\n* Refusal to participate\n* Presence of orthopedic conditions that prevent walking (e.g., amputation, joint prosthesis)","ALL","18 Years",{"count":67,"type":68},100,"ESTIMATED","OBSERVATIONAL","Knee osteoarthritis is a common joint disease that causes pain, stiffness, and limitations in daily activities, especially in older adults. Changes in the alignment of the lower limb, called the anatomical axis, can increase the mechanical load on the knee joint and may affect pain and mobility. This study aims to investigate the relationship between the anatomical axis measured on knee X-rays and patients' pain levels, functional status, quality of life, and fear of movement (kinesiophobia).\n\nThis is a single-center, observational, cross-sectional study. Adult patients diagnosed with knee osteoarthritis who have a standard knee X-ray taken within the last 6 months and who volunteer to participate will be included. Pain will be measured with the Visual Analog Scale (VAS), functional status with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), quality of life with the 36-Item Short Form Health Survey (SF-36), and kinesiophobia with the Tampa Scale for Kinesiophobia (TSK). The femoro-tibial angle and joint space width will be measured on X-rays by two independent observers.\n\nBy examining the relationship between radiographic alignment and clinical findings, this study may provide new insights into the comprehensive evaluation of knee osteoarthritis and help guide treatment planning for patients.",[72,73,74],"Knee Osteoarthritis","Pain","Kinesiophobia",[76,77,78,79,80,81,73,82,74],"Knee osteoarthritis","Anatomical axis","Radiographic alignment","Tampa Scale for Kinesiophobia (TSK)","SF-36","WOMAC","Femoro-tibial angle","2026-05-22",{"date":85,"type":86},"2026-05-26","ACTUAL",{"date":88,"type":86},"2025-09-08",{"date":90,"type":68},"2026-09-08",{"name":54,"class":6},1]