[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612618":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":19,"locations":27,"responsibleParty":44,"collaborators":48,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":10,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Phase 1",null,"The Phase 1 cohort comprises all participants enrolled during the first phase of the APECx study. The primary focus for this phase\u002Fgroup is to identify global mechanical ventilation strategies and their associations with key clinical outcomes, including the incidence of post-operative pulmonary complications.",[13,17],{"name":14,"affiliation":15,"role":16},"Anne M Beukers, MD, PhD","Amsterdam UMC","STUDY_CHAIR",{"name":18,"affiliation":15,"role":16},"David MP van Meenen, MD, PhD",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Jord C Seegers, MD","CONTACT","+3120 566 9111","apecx@amsterdamumc.nl",{"name":14,"role":22,"phone":10,"phoneExt":10,"email":26},"a.beukers@amsterdamumc.nl",[28],{"facility":29,"status":10,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Amsterdam UMC, Location AMC","Amsterdam","North Holland","1105AZ","Netherlands","NL",{"type":36,"coordinates":37},"Point",[38,39],4.88969,52.37403,{"lat":39,"lon":38},[42],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":43},"j.c.seegers@amsterdamumc.nl",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Nimrat Grewal","Professor and Principal Investigator",[49,51],{"name":50,"class":6},"Amsterdam UMC, location AMC",{"name":52,"class":6},"VU University of Amsterdam","100612618","anesthesia-perfusion-and-surgical-practices-in-cardiac-surgery-100612618",false,"NCT07255924","Anesthesia, Perfusion, and Surgical practicEs in Cardiac Surgery","Anesthesia, Perfusion, and Surgical practicEs in Cardiac Surgery: an Adaptive, Prospective, International, Multicenter, Observational Study.","APECx","Inclusion Criteria:\n\n* 18 years or older\n* Undergoing cardiac surgery at a participating center\n\nExclusion Criteria:\n\n\\- Transcatheter cardiac interventions or endovascular procedures","ALL","18 Years",{"count":64,"type":65},15000,"ESTIMATED","OBSERVATIONAL","Perioperative management in cardiac surgery, particularly the use of anesthesia, cardiopulmonary bypass (CPB), and surgical techniques, remains highly variable across institutions. Current international guidelines lack clear recommendations due to insufficient high-quality comparative data. APECx is an adaptive, international, multicenter, prospective, observational study designed to address multiple of these evidence gaps. The adaptive design allows the study to proceed through subsequent phases. Each phase will collect comprehensive global data on specific peri-operative practices and their associated patient outcomes, all within a single, continuously evolving study.",[69,70,71,72],"Cardiac Anaesthesia","Cardiac Surgery","Perfusion","Anesthesia",[70,69,72,71],"NOT_YET_RECRUITING","2025-11-27",{"date":77,"type":78},"2025-12-01","ACTUAL",{"date":80,"type":65},"2026-04-01",{"date":82,"type":65},"2036-01",{"name":5,"class":6},1]