[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525564":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":35,"responsibleParty":56,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Saint Thomas Hospital, Panama","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"39 weeks","EXPERIMENTAL","Patients with gestational hypertension and angiogenic factors (sFlt-1\u002FPIGF) below 33 will be evaluated weekly until 39 weeks, when termination of pregnancy will be scheduled.",[13],"Diagnostic Test: Angiogenic factor",{"label":15,"type":16,"description":17,"interventionNames":18},"37 weeks","ACTIVE_COMPARATOR","Patients with gestational hypertension and angiogenic factors (sFlt-1\u002FPIGF) below 33 will be evaluated weekly until 37 weeks, when termination of pregnancy will be scheduled.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIAGNOSTIC_TEST","Angiogenic factor","sFLt-1\u002FPGIF below or equal to 33",[15,9],null,[27,32],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Osvaldo Reyes, MD","CONTACT","+507 65655041","oreyespanama@yahoo.es",{"name":33,"role":29,"phone":25,"phoneExt":25,"email":34},"Gerado Cardenas, MD","drgacardenas@hotmial.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Hospital Santo Tomas","RECRUITING","Panama City","Provincia de Panamá","0834-1439","Panama","PA",{"type":45,"coordinates":46},"Point",[47,48],-79.51973,8.9936,{"lat":48,"lon":47},[51,53],{"name":28,"role":29,"phone":52,"phoneExt":25,"email":31},"50765655041",{"name":54,"role":29,"phone":25,"phoneExt":25,"email":55},"Gerardo Cardenas, MD","drgacardenas@hotmail.com",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Osvaldo A. Reyes T.","Head of the research deparment","100525564","angiogenic-factors-in-the-conservative-management-of-gestational-hypertension-100525564",false,"NCT06123377","Angiogenic Factors in the Conservative Management of Gestational Hypertension","Use of Angiogenic Factors in the Conservative Management of Gestational Hypertension. Prospective, Randomised, Controlled Study.","Inclusion Criteria:\n\n* Pregnant women between 24 and 40 weeks of gestation.\n* Diagnosis of Gestational Hypertension based on ACOG criteria\n* index sFlt-1\u002FPIGF equal or below 33\n\nExclusion Criteria:\n\n* Multiple gestation\n* Maternal vasculitis\n* Previous cesarean section (3 or more)\n* Neurological conditions\n* Chronic renal disease\n* Purpura\n* Heart disease\n* Index sFlt-1\u002FPIGF of 34 or more","FEMALE","18 Years",{"count":70,"type":71},150,"ESTIMATED","INTERVENTIONAL",[74],"NA","Hypertensive disorders of pregnancy (HPT) are an important cause of maternal-feto-neonatal morbidity and mortality, being one of the three leading causes of maternal death in our country and in developing countries. The only cure for THE is termination of pregnancy, which ends up being a decision in which gestational age and maternal risks must be balanced. Angiogenic factors have come to occupy an indispensable place in the arsenal of tools that can be used to separate the patient with a high likelihood of complications from those in whom prolongation of pregnancy could represent an important neonatal benefit. One of the most controversial scenarios is gestational hypertension, a group of hypertensive disorders considered the mildest form of the pre-eclamptic spectrum, where current recommendations indicate termination of pregnancy at 37 weeks. However, the decision is based on outdated guidelines developed at a time when angiogenic factors were just beginning to be known. The purpose of the study is to use angiogenic factors as a guide to decide the most appropriate gestational age for termination of pregnancy in patients diagnosed with gestational hypertension.",[77],"Gestational Hypertension",[79,80],"Gestational hypertension","Angiogenic factors","2025-08-23",{"date":83,"type":84},"2025-08-26","ACTUAL",{"date":86,"type":84},"2024-06-01",{"date":88,"type":71},"2026-09-30",{"name":5,"class":6},1]