[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583792":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":55,"collaborators":57,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Qilu Hospital of Shandong University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Krill Oil Functional Food Group","EXPERIMENTAL","Dosage: 2 g of krill oil per day, orally administered. Specification: Krill oil capsules are provided in 1 g\u002Fcapsule format. Administration: Take 1 capsule 30 minutes after breakfast and 1 capsule 30 minutes after dinner.\n\nNote: The Antarctic krill oil functional food used in this study is produced and supplied by Jinan Jiyuan Biotechnology Co., Ltd. Its main components include phospholipids, DHA, EPA, and astaxanthin.\n\nDuration: Administration begins on the day of the first bladder instillation treatment and continues until the day of the last bladder instillation treatment.\n\nForm: Capsule form for convenient oral administration.",[13],"Dietary Supplement: Krill Oil Functional Food",{"label":15,"type":16,"description":17,"interventionNames":18},"Olive Oil Group","PLACEBO_COMPARATOR","Intervention:Participants will not orally consume krill oil. Instead, they will receive placebo capsules that are visually identical to krill oil capsules.The placebo capsules contain olive oil.Each capsule is 1g in size.\n\nDosage and Administration:Take 1 capsule after breakfast and 1 capsule after dinner, within 30 minutes of each meal.\n\nDuration:The intervention will begin on the day of the first bladder instillation treatment.It will continue until the day of the last bladder instillation treatment.",[19],"Dietary Supplement: Olive Oil",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Krill Oil Functional Food","Take 2g of krill oil orally daily, with each krill oil capsule containing 1g, by consuming one capsule within 30 minutes after breakfast and one capsule within 30 minutes after dinner. The supplementation period begins on the day of the first bladder instillation treatment and continues until the day of the last bladder instillation treatment.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Olive Oil","Instead of taking krill oil orally, use placebo capsules that are visually similar, with the contents being olive oil, each capsule containing 1g. Take one capsule within 30 minutes after breakfast and one capsule within 30 minutes after dinner. The duration of intake begins on the day of the first bladder instillation treatment and continues until the day of the last bladder instillation treatment.",[15],[32],{"name":33,"affiliation":5,"role":34},"weiqiang Jing, PhD","STUDY_CHAIR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","0086-13256102995","wjing1@sdu.edu.cn",[41],{"facility":5,"status":26,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Jinan","Shandong","250000","China","CN",{"type":48,"coordinates":49},"Point",[50,51],116.99722,36.66833,{"lat":51,"lon":50},[54],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},{"type":56,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[58,60],{"name":59,"class":6},"The Affiliated Hospital of Qingdao University",{"name":61,"class":62},"Shandong Provincial Hospital","OTHER_GOV","100583792","antarctic-krill-oil-functional-food-mitigates-bladder-cancer-treatment-side-effects-100583792",false,"NCT06880939","Antarctic Krill Oil Functional Food Mitigates Bladder Cancer Treatment Side Effects","Randomized, Double-Blind, Parallel-Controlled, Multicenter Clinical Study on the Efficacy of Antarctic Krill Oil Functional Food in Alleviating Side Effects of Intravesical Therapy for Bladder Cancer","Inclusion Criteria:\n\n* 1\\. Diagnosed bladder cancer: The patient needs to be diagnosed with bladder cancer through pathological examination and have undergone bladder cancer surgery.\n* 2\\. Planned to receive bladder infusion therapy: Patients need to plan to receive bladder infusion therapy after surgery and agree to participate in the study.\n* 3\\. Age range: 18 to 75 years old.\n* 4\\. Normal blood, liver and kidney function: Laboratory tests showed that the patient's blood routine, liver function and kidney function were within the normal range.\n* 5\\. Signed informed consent: The patient understands the content of the study and voluntarily signs the informed consent.\n\nExclusion Criteria:\n\n* 1\\. Serious comorbidities: including but not limited to heart disease, severe liver and kidney insufficiency, uncontrolled hypertension, diabetes, etc.\n* 2\\. History of allergies: Patients with a known history of allergy to krill oil or perfusion drug components.\n* 3\\. History of prior chemotherapy: Patients who have received perfusion therapy prior to this study.\n* 4\\. History of other malignant tumors: Patients with a history of other malignant tumors.\n* 5\\. Pregnancy or lactation: Female patients who are pregnant or lactating.\n* 6\\. Psychiatric illness: Patients with a history of severe psychiatric illness or currently receiving treatment for psychiatric illness.\n* 7\\. Poor study compliance: Patients who believe that they are unable to complete the entire trial process as required by the study.\n* 8\\. Other: Other conditions that the investigator considers unsuitable to participate in this study.","ALL","18 Years","75 Years",{"count":74,"type":75},210,"ESTIMATED","INTERVENTIONAL",[78],"NA","This randomized, double-blind, placebo-controlled, multicenter trial evaluates the efficacy and safety of Antarctic krill oil in reducing side effects of intravesical therapy for non-muscle-invasive bladder cancer (NMIBC). A total of 210 participants (18-75 years) will be randomized to receive either 2g\u002Fday of krill oil capsules (containing phospholipids, DHA, EPA, and astaxanthin) or placebo during intravesical treatment (epirubicin, pirarubicin, or BCG).\n\nPrimary outcomes include bladder irritation symptoms (IPSS score), systemic adverse events, hematuria, and urinary tract infections. Secondary outcomes assess quality of life (QoL). Safety will monitor adverse events per CTCAE v5.0.\n\nThe study follows GCP standards and includes rigorous data management and ethical oversight. Results may offer a dietary intervention to improve treatment tolerance and QoL for bladder cancer patients.",[81],"Urinary Bladder Neoplasms",[83,84,85,86,87],"Bladder Cancer","Krill Oil","Intravesical Therapy","Adverse Effects","Randomized Controlled Trial","NOT_YET_RECRUITING","2025-07-20",{"date":91,"type":92},"2025-07-24","ACTUAL",{"date":94,"type":75},"2025-07-15",{"date":96,"type":75},"2028-05-30",{"name":5,"class":6},1]