[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593197":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":44,"responsibleParty":65,"collaborators":26,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":26,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":26,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":46,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Anterior Approach Group","EXPERIMENTAL","Participants will undergo upper eyelid ptosis correction using the anterior approach, involving a skin incision through the upper eyelid crease to access the levator aponeurosis",[13],"Procedure: Anterior White Line Advancement Surgery",{"label":15,"type":16,"description":17,"interventionNames":18},"Posterior Approach Group","ACTIVE_COMPARATOR","Participants will undergo upper eyelid ptosis correction using the posterior approach, which avoids skin incision and accesses the levator aponeurosis via the conjunctiva.",[19],"Procedure: Posterior White Line Advancement Surgery",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Anterior White Line Advancement Surgery","This technique involves a skin incision at the eyelid crease, dissection through the orbicularis muscle to expose the tarsus, and proximal dissection in the pre-Müller-conjunctival plane to visualize the white line. A double-armed 5-0 absorbable suture is used to advance the white line to the anterior tarsal surface. Eyelid height and contour are assessed before final fixation. Skin closure is completed with a non-absorbable suture.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Posterior White Line Advancement Surgery","This conjunctival technique uses a traction suture and eyelid eversion to access the posterior surface of the eyelid. A conjunctival incision is made above the superior tarsal border, followed by dissection to expose the white line. A double-armed 5-0 absorbable suture is passed through the anterior tarsus and the white line, and tied after confirming adequate eyelid position. The conjunctiva is not sutured.",[15],[32],{"name":33,"affiliation":34,"role":35},"Viviana Patricia Lezcano Carduz, MD","Rey Juan Carlos Hospital","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+34 914816225","viviana.lezcano@quironsalud.es",{"name":42,"role":38,"phone":39,"phoneExt":26,"email":43},"Francisco Javier González García, MD, PhD","fjavier.gonzalez@hospitalreyjuancarlos.es",[45],{"facility":34,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Móstoles","Madrid","28932","Spain","ES",{"type":53,"coordinates":54},"Point",[55,56],-3.86496,40.32234,{"lat":56,"lon":55},[59,62,64],{"name":60,"role":38,"phone":39,"phoneExt":26,"email":61},"Viviana Patricia Lezcano Carduz, Principal Investigator","viviana.lezcano@hospitalreyjuancarlos.es",{"name":63,"role":38,"phone":39,"phoneExt":26,"email":43},"Francisco Javier González García, Site Sub-Investigator",{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"type":35,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Viviana Patricia Lezcano Carduz","Principal Investigator.","100593197","anterior-versus-posterior-white-line-advancement-technique-in-the-correction-of-aponeurotic-ptosis-100593197",false,"NCT07003308","Anterior Versus Posterior White Line Advancement Technique in the Correction of Aponeurotic Ptosis","Comparative Study of the Efficacy of Anterior Versus Posterior White Line Advancement Technique in the Correction of Primary Aponeurotic Ptosis","Inclusion Criteria:\n\n* Age over 18 years.\n* Diagnosis of primary aponeurotic upper eyelid ptosis.\n* Levator muscle function of 12 mm or greater.\n* Provision of written informed consent after receiving adequate information about the study.\n\nExclusion Criteria:\n\n* Diagnosis of non-aponeurotic eyelid ptosis.\n* Poor levator muscle function.\n* History of recurrent eyelid ptosis or previous eyelid ptosis surgery.\n* Medical or surgical history that, in the investigator's judgment, may interfere with participation.\n* Individuals with childbearing potential who are not using highly effective contraception methods.\n* Refusal to participate in the study or to sign the informed consent form.","ALL","18 Years",{"count":78,"type":79},54,"ESTIMATED","INTERVENTIONAL",[82],"NA","The goal of this clinical trial is to compare the efficacy of two surgical techniques-anterior and posterior white line advancement-for the correction of primary aponeurotic ptosis in adult patients. The main questions it aims to answer are:\n\nDoes the anterior approach lead to a greater improvement in Marginal Reflex Distance 1 (MRD1) at 6 months compared to the posterior approach?\n\nAre there differences in eyelid symmetry, contour, visual function, and patient satisfaction between the two techniques?\n\nResearchers will compare the anterior approach group to the posterior approach group to see if one offers better functional and aesthetic outcomes, fewer complications, or higher patient satisfaction.\n\nParticipants will:\n\nBe randomly assigned to receive either anterior or posterior white line advancement surgery.\n\nUndergo preoperative and postoperative evaluations at 7 days, 2 months, and 6 months, including:\n\nMeasurements of eyelid position (MRD1), contour, and symmetry\n\nVision and tear film tests (e.g., refraction, TBUT, Schirmer's test)\n\nSurveys on dry eye symptoms (OSDI), scar quality (POSAS 2.0), satisfaction, and psychosocial function\n\nMonitoring of surgical time and complications",[85],"Ptosis, Eyelid",[87,88,89,90,91],"eyelid","levator palpebrae","oculoplastic surgery","ophthalmology","blepharoptosis","2025-10-02",{"date":94,"type":95},"2025-10-07","ACTUAL",{"date":97,"type":95},"2025-06-01",{"date":99,"type":79},"2027-01-30",{"name":5,"class":6},1]