[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641317":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":11,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":11,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":11,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Anhui Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Anti-inflammatory Diet Intervention Group","EXPERIMENTAL",null,[13],"Behavioral: Anti-inflammatory Dietary Intervention",{"label":15,"type":16,"description":11,"interventionNames":17},"Standard Diabetes Diet Control Group","ACTIVE_COMPARATOR",[18],"Behavioral: Standard Diabetes Dietary Advice",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","Anti-inflammatory Dietary Intervention","Participants in this group will receive a 4-week evidence-based anti-inflammatory dietary intervention in addition to routine diabetes care.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Standard Diabetes Dietary Advice","Participants will receive routine dietary guidance for diabetes management according to standard clinical dietary recommendations for 4 weeks.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Huimin Guo","CONTACT","+8615399593640","2445011323@stu.ahmu.edu.cn",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"The First Affiliated Hospital of Anhui Medical University","RECRUITING","Hefei","Anhui","230000","China","CN",{"type":45,"coordinates":46},"Point",[47,48],117.28083,31.86389,{"lat":48,"lon":47},[51],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Guo Huimin","Graduate Student","100641317","anti-inflammatory-dietary-intervention-in-patients-with-type-2-diabetes-a-randomized-controlled-trial-100641317",false,"NCT07656805","Anti-inflammatory Dietary Intervention in Patients With Type 2 Diabetes: A Randomized Controlled Trial","Evidence-based Construction and Application of an Anti-inflammatory Diet Intervention for Patients With Type 2 Diabetes Mellitus","Inclusion Criteria:\n\n1. Patients who meet the diagnostic criteria for type 2 diabetes mellitus (T2DM) according to the Guidelines for the Prevention and Treatment of Type 2 Diabetes Mellitus in China (2020 Edition);\n2. Aged 18 years or older;\n3. Able and willing to complete all study questionnaires;\n4. Willing to provide blood samples for laboratory testing;\n5. Possessing adequate communication and comprehension abilities, with no impairment of consciousness, and able to respond to investigators' questions;\n6. Willing to participate in regular follow-up visits and assessments according to the study protocol and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Patients with a history of diseases affecting blood glucose metabolism, such as hyperthyroidism or Cushing's syndrome;\n2. Pregnant or breastfeeding women;\n3. Patients with severe hepatic dysfunction, renal dysfunction, heart failure, or malignant tumors;\n4. Patients with acute or chronic infectious diseases accompanied by obvious signs of infection, including clinically diagnosed intestinal infections, respiratory tract infections, periodontitis, and other infectious conditions;\n5. A history of recent use of medications that may affect inflammatory or metabolic status, such as nonsteroidal anti-inflammatory drugs (NSAIDs, e.g., aspirin) or glucocorticoids;\n6. Patients who have undergone gastrointestinal surgery or have diseases that may affect the effectiveness of dietary intervention, such as malabsorption syndrome.","ALL","18 Years",{"count":66,"type":67},88,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of this clinical trial is to evaluate whether an evidence-based anti-inflammatory dietary intervention can reduce inflammation and improve glycemic control in patients with type 2 diabetes mellitus (T2DM). T2DM is a chronic metabolic disease characterized by elevated blood glucose levels and is closely associated with chronic low-grade inflammation.\n\nThe main questions it aims to answer are:\n\nDoes an anti-inflammatory dietary intervention reduce levels of hs-CRP, a key marker of chronic inflammation, in patients with T2DM? Does the intervention improve dietary inflammatory index (DII) scores and glycemic outcomes, including fasting blood glucose and 2-hour postprandial blood glucose? Researchers will compare an anti-inflammatory diet intervention group to a standard diabetes dietary control group to determine whether the anti-inflammatory dietary pattern provides additional benefits beyond routine dietary management.\n\nParticipants will:\n\nBe randomly assigned to either the anti-inflammatory diet group or the standard diabetes diet group Receive dietary guidance based on structured anti-inflammatory food recommendations or routine diabetes dietary advice Complete dietary assessments, including 24-hour dietary recalls to calculate dietary inflammatory index (DII) Provide blood samples to measure hs-CRP, fasting blood glucose, and 2-hour postprandial blood glucose at baseline and after 4 weeks Complete questionnaires on dietary adherence and quality of life Participate in a 4-week intervention period with follow-up assessments",[73],"T2DM (Type 2 Diabetes Mellitus)","2026-06-14",{"date":76,"type":77},"2026-06-18","ACTUAL",{"date":79,"type":77},"2026-06-03",{"date":81,"type":67},"2026-11",{"name":5,"class":6},1]