[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631198":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":24,"responsibleParty":52,"collaborators":55,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":18,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":18,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":27,"whyStopped":18,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Universidad Autonoma de Nuevo Leon","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pecan nut oil supplementation","EXPERIMENTAL","Participants in the experimental group will receive daily supplementation with pecan nut oil. The oil will be administered orally in standardized dose of 30 mL\u002Fday for a period of 60 days. The intervention aims to evaluate the anti-inflammatory effects and impact on metabolic and biochemical parameters in adults with overweight.",[13],"Dietary Supplement: Pecan nut oil supplementation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Participants in the control group will not receive any supplementation and will be intructed to maintain their usual diet and lifestyle throughout the study period.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"DIETARY_SUPPLEMENT","Pecan nut oil will be administered as a dietary supplement by oral intake in a standardized daily dose of 30 mL\u002Fday for 60 days. The oil will be obtained through cold pressing, ensuring minimal processing and preservation of its bioactive compounds, particularly unsaturated fatty acids and antioxidants constituents.\n\nThis intervention is distinguished from conventional dietary interventions by the use of a regionally sourced pecan nut oil with defined physicochemical and oxidative stability characteristics, allowing for controlled evaluation of its nutraceutical potencial. Unlike general dietary modifications, this study focuses on a single, standardized bioactive source to specifically assess its role in modulating inflammatory biomarkers and metabolic parameters in adults with overweight.",[9],[25],{"facility":26,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Facultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León","RECRUITING","Monterrey","Nuevo León","64460","Mexico","MX",{"type":34,"coordinates":35},"Point",[36,37],-100.31721,25.68435,{"lat":37,"lon":36},[40,46,50],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Heriberto Castro García, PhD","CONTACT","+52 8113404890","3081","heriberto.castrogr@uanl.edu.mx",{"name":47,"role":42,"phone":48,"phoneExt":18,"email":49},"Aurora Stephanie Hilario-Azuara, QFBT","+528146308248","auhilario_al@ciatej.edu.mx",{"name":41,"role":51,"phone":18,"phoneExt":18,"email":18},"PRINCIPAL_INVESTIGATOR",{"type":51,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Heriberto Castro Garcia","Proffessor and Researcher, Facultad de Salud Publica y Nutricion",[56,58],{"name":57,"class":6},"Hospital Universitario Dr. Jose E. Gonzalez",{"name":59,"class":60},"Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco","UNKNOWN","100631198","anti-inflammatory-effects-of-pecan-nut-oil-supplementation-in-adults-with-overweight-a-randomized-controlled-parallel-group-clinical-trial-100631198",false,"NCT07497555","Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial","Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Non-Randomized Controlled Parallel-Group Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n* Body mass index (BMI) ≥25 and \\\u003C30 kg\u002Fm² (overweight)\n* Willingness to participate and provide written informed consent\n* Ability to comply with study procedures and attend scheduled visits\n* Stable dietary habits and physical activity levels during the study period\n\nExclusion Criteria:\n\n* Diagnosis of chronic diseases such as diabetes mellitus, cardiovascular disease, liver disease, renal disease, or autoimmune disorders\n* Use of anti-inflammatory medications, lipid-lowering drugs, or dietary supplements within the last 3 months\n* Smoking or excessive alcohol consumption\n* Pregnancy or lactation\n* Known allergy or intolerance to nuts or nut-derived products\n* Participation in another clinical trial within the last 3 months\n* Any condition that, in the investigator's opinion, may interfere with study participation or outcomes",true,"ALL","18 Years","55 Years",{"count":73,"type":74},50,"ESTIMATED","INTERVENTIONAL",[77],"NA","The goal of this clinical trial is to evaluate whether daily supplementation with cold-pressed pecan nut oil can reduce inflammation in adults with overweight. The main questions it aims to answer are:\n\nDoes pecan nut oil supplementation reduce inflammatory biomarkers, including C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α)? Does pecan nut oil supplementation improve biochemical parameters such as fasting blood glucose and lipid profile? Researchers will compare an experimental group receiving pecan nut oil to a control group with no intervention to determine its effect on inflammation and metabolic parameters.\n\nParticipants will:\n\nConsume 30 g\u002Fday of cold-pressed pecan nut oil under fasting conditions for 8 weeks (experimental group) Maintain their usual diet and physical activity throughout the study Attend two evaluation visits (baseline and Day 60) for blood sample collection and anthropometric measurements Provide dietary information using a 24-hour dietary recall",[80],"Overweight (BMI > 25)",[82,83,84,85,86],"pecan nut oil","overweight","controlled trial","nutraceuticals","chronic low-grade inflammation","2026-03-23",{"date":89,"type":90},"2026-03-27","ACTUAL",{"date":92,"type":90},"2025-10-15",{"date":94,"type":74},"2026-07-30",{"name":5,"class":6},1]