[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626457":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":61,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":91,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Future University in Egypt","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"triton group","EXPERIMENTAL","Participants receive root canal treatment using the Triton irrigation protocol for disinfection of necrotic mandibular molars. The protocol is applied according to the manufacturer's instructions during chemo-mechanical preparation.",[13],"Procedure: triton irrigation protocol",{"label":15,"type":16,"description":17,"interventionNames":18},"conventional irrigation group","ACTIVE_COMPARATOR","Participants receive root canal treatment using conventional syringe irrigation with sodium hypochlorite during chemo-mechanical preparation.",[19],"Procedure: conventional irrigation group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","triton irrigation protocol","Root canal irrigation performed using Triton solution according to a standardized endodontic irrigation protocol during root canal treatment.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Participants receive conventional root canal irrigation using standard irrigation solutions during chemo-mechanical preparation according to the routine clinical protocol.",[15],[31],{"name":32,"affiliation":33,"role":34},"sara hosny mostafa adly, BDS","faculty of oral and dental medicine , future university in egypt","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","00201009568678","drsarahosny45@yahoo.com",[41],{"facility":42,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Faculty of Oral and Dental Medicine , Future University in Egypt","Cairo","New Cairo","11835","Egypt","EG",{"type":49,"coordinates":50},"Point",[51,52],31.24967,30.06263,{"lat":52,"lon":51},[55,56,59],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},{"name":57,"role":58,"phone":26,"phoneExt":26,"email":26},"reham hassan, PHD","SUB_INVESTIGATOR",{"name":60,"role":58,"phone":26,"phoneExt":26,"email":26},"hesham salah, MSc",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","sara hosny mostafa","postgraduate dentist","100626457","antibacterial-effect-and-postoperative-pain-after-triton-irrigation-protocol-in-necrotic-mandibular-molar-100626457",false,"NCT07435883","Antibacterial Effect and Postoperative Pain After Triton Irrigation Protocol in Necrotic Mandibular Molar","Evaluation of Antibacterial Effect and Postoperative Pain Following Irrigation Protocol Using Triton in Necrotic Mandibular Molars. A Randomized Clinical Control Trial","Inclusion Criteria:\n\n* Patients aged 18-45 years with no sex predilection\n* Medically free Patients with no systemic conditions that can affect post operative pain response.\n* Patients should not be taking any pain medications 24 hours before intervention\n* Positive patients' acceptance for participating in the study\n* Patient able to sign informed consent\n* Permanent mandibular molars diagnosis with pulpal necrosis with asymptomatic apical periodontitis.\n* Mandibular molars without any anatomical variations or severe curvatures with mesial roots configuration weine class 3 and a distal root with 2 distal canals\n\nExclusion Criteria:\n\n* Medically compromised patients\n\n  * Patients who have received antibiotic therapy within the last 2 weeks.\n  * Pregnant or lactating women.\n  * Patients with known allergy to any of the irrigants used.\n  * Patients with swelling or acute peri-apical abscess or fistulous tract.\n  * Teeth that have:\n  * Wide or open apex .\n  * Vital pulp tissue .","ALL","18 Years","45 Years",{"count":76,"type":77},36,"ESTIMATED","INTERVENTIONAL",[80],"NA","This randomized clinical study evaluates the antibacterial effectiveness and postoperative pain following root canal irrigation using the Triton irrigation protocol in necrotic mandibular molars. Thirty-six patients requiring root canal treatment will be included. The study aims to compare bacterial reduction and postoperative pain outcomes after treatment. Results may help improve irrigation protocols and patient comfort during endodontic therapy.",[83],"Pulp Necrosis",[85,86,87,88,89,90],"root canal treatment","endodontics","irrigation protocol","triton irrigation","postoperative pain","antibacterial effect","NOT_YET_RECRUITING","2026-02-21",{"date":94,"type":95},"2026-02-27","ACTUAL",{"date":97,"type":77},"2026-03",{"date":99,"type":77},"2026-10",{"name":63,"class":6},1]