[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491444":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":59,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":10,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":10,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Insel Gruppe AG, University Hospital Bern","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Preeclampsia and obstetric Antiphospholipid Syndrome",null,"Women in this group wil be followed during 3 years. Echocardiography images, 24-hour ambulatory blood pressure monitoring will be collected.",[13,14],"Diagnostic Test: Echocardiography images","Diagnostic Test: 24-hour ambulatory blood pressure monitoring",{"label":16,"type":10,"description":11,"interventionNames":17},"Preeclampsia without obstetric Antiphospholipid Syndrome",[13,14],[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","Echocardiography images","Transthoracic echocardiographic (Vivid E95) performed in all included patients between three months and three years after delivery.\n\n* Left ventricular ejection fraction,\n* Left ventricular mass index,\n* Septal and lateral mitral annular E-wave velocity assessed by tissue Doppler,\n* Tricuspid annular plane systolic excursion,\n* Left atrial volume index,\n* Right ventricle to right atrium (RV\u002FRA) gradient",[9,16],{"type":20,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"24-hour ambulatory blood pressure monitoring","Twenty-four-hour ABPM performed between three months and three years after delivery using validated recorders (Spacelabs model 90217, USA)",[9,16],[29],{"name":30,"affiliation":31,"role":32},"Emrush Rexhaj, MD","Insel Gruppe AG, Inselspital, Bern","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","+41 31 632 21 11","emrush.rexhaj@insel.ch",[39],{"facility":40,"status":41,"city":42,"state":10,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Inselspital","RECRUITING","Bern","3010","Switzerland","CH",{"type":47,"coordinates":48},"Point",[49,50],7.44744,46.94809,{"lat":50,"lon":49},[53,55],{"name":30,"role":35,"phone":54,"phoneExt":10,"email":37},"+41316322111",{"name":56,"role":35,"phone":57,"phoneExt":10,"email":58},"Theo Meister, MD","+41316321890","theo.meister@insel.ch",{"type":32,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Emrush Rexhaj","Head of Hypertension, Principal Investigator","100491444","antiphospholipid-syndrome-and-postpartum-pulmonary-artery-pressure-100491444",false,"NCT05679206","Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure","Association Between Preeclampsia, Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure, Systemic Arterial Pressure and Cardiovascular Function.","Inclusion Criteria:\n\n* Age: \\> 16 years.\n* Consent or waiver of consent according Chapter 9\n* Preeclampsia\n\nDefined as:\n\n• New onset hypertension (blood pressure \\>140\u002F90mmHg on multiple occasions after 20 weeks of gestation)\n\nIn combination with new onset of 1 or more of the following:\n\n* Proteinuria (urine protein \\>300mg \u002F24h or 2+ or higher in dipstick on multiple occasions)\n* Platelet count \\\u003C100,000\u002FmicroL,\n* Serum creatinine \\>97.2 micromol\u002FL,\n* Liver transaminases at least twice the upper limit of the normal concentrations,\n* Pulmonary edema,\n* New-onset and persistent headache,\n* Visual symptoms. -Postnatal follow up at the obstetrical and cardiology clinic, Inselspital Bern, Switzerland.\n\nExclusion Criteria:\n\n* Age: \\\u003C 16 years\n* Incomplete or ambiguous data: if data confirming the eligibility criteria or data to analyze the primary endpoint is not fully available or despite efforts assessed as significantly ambiguous, the data set will be excluded from analyses, since no analysis is possible","FEMALE","16 Years",{"count":72,"type":73},900,"ESTIMATED","OBSERVATIONAL","The primary goal of this observational study is to learn about postpartum pulmonary artery pressure in women who suffered from Preeclampsia and Antiphospholipid Syndrome.\n\nThe main question it aims to answer is whether the conjunction of preeclampsia with obstetric antiphospholipid syndrome significantly foster the development of long-lasting pulmonary hypertension.\n\nOnly participants who suffered from preeclampsia during pregnancy will be followed for a period up to 3 years postpartum. Researchers will compare women with or without obstetric antiphospholipid syndrome.",[77,78,79],"Pre-Eclampsia; Complicating Pregnancy","Antiphospholipid Syndrome in Pregnancy","Pulmonary Hypertension",[81,78,79],"Pre-Eclampsia","2024-05-08",{"date":84,"type":85},"2024-05-09","ACTUAL",{"date":87,"type":85},"2022-12-20",{"date":89,"type":73},"2028-12-31",{"name":5,"class":6},1]