[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643486":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":13,"locations":22,"responsibleParty":37,"collaborators":41,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":7,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":7,"enrollmentInfo":53,"targetDuration":7,"studyType":56,"phases":7,"briefSummary":57,"conditions":58,"keywords":7,"overallStatus":60,"whyStopped":7,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","D-dimer test","The patient will receive a ADD-RS calculated by the clinician, evaluating high-risk conditions, high-risk pain features and high-risk physical signs of AAS. A point-of-care D-dimer test will be performed after routine blood taking. The research personnel will collect the above data from the clinician.",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Colin Graham, Professor","CONTACT","+852 35051698","cagraham@cuhk.edu.hk",{"name":20,"role":16,"phone":21,"phoneExt":7,"email":7},"Rebecca Li, Miss","35051698",[23],{"facility":24,"status":7,"city":25,"state":7,"zip":7,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Prince of Wales Hospital","Shatin","Hong Kong","HK",{"type":29,"coordinates":30},"Point",[31,32],114.18333,22.38333,{"lat":32,"lon":31},[35],{"name":36,"role":16,"phone":21,"phoneExt":7,"email":7},"Rebecca Li",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Colin Graham","Professor",[42],{"name":43,"class":6},"Prince of Wales Hospital, Shatin, Hong Kong","100643486","aortic-dissection-detection-risk-score-with-d-dimer-to-rule-out-acute-aortic-syndrome-100643486",false,"NCT07640334","Aortic Dissection Detection Risk Score With D-dimer to Rule-Out Acute Aortic Syndrome","The Combination of Aortic Dissection Detection Risk Score With D-dimer to Rule-Out Acute Aortic Syndrome: Multicentre Prospective Study in Emergency Departments","Inclusion Criteria:\n\n* Adult patients aged ≥ 18 years; AND\n* Presentation to the ED with any of the following symptoms: acute onset (\\\u003C14 days) chest pain, abdominal pain, back pain, syncope, or signs of malperfusion (e.g. limb ischemia, neurological deficit); AND\n* AAS is considered as a possible differential diagnosis by the treating physician. Enrolment in the study will be determined by the attending physician during initial medical consultation in the ED and prior to establishing a final diagnosis.\n\nExclusion Criteria:\n\n* An alternative diagnosis to AAS established by the treating physician after the initial assessment; OR\n* Trauma cases; OR\n* Patients with a known diagnosis of AAS before the index ED visit (e.g. with a diagnostic imaging done before the ED visit or referral from other institutions for AAS); OR\n* Clinical severity or other conditions not allowing complete evaluation\u002Fproper enrolment; OR\n* Patient who refuse to participate.","ALL","18 Years",{"count":54,"type":55},448,"ESTIMATED","OBSERVATIONAL","The goal of this study is to evaluate the safety of integrating the Aortic Dissection Detection Risk Score (ADD-RS) and D-dimer testing for ruling out acute aortic syndrome (AAS) in the emergency department (ED). The main question it aims to answer: Can the combination of the ADD-RS \\\u003C2, and D dimer \\\u003C500ng\u002FmL rule-out AAS in ED patients without CTA? The researchers will recruit patients suspected with AAS in the ED, and the patients will receive a ADD-RS score, a D-dimer testing after signing a written consent.",[59],"Acute Aortic Syndrome","NOT_YET_RECRUITING","2026-06-08",{"date":63,"type":64},"2026-06-10","ACTUAL",{"date":66,"type":55},"2026-07-13",{"date":68,"type":55},"2028-12-31",{"name":5,"class":6},1]