[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525705":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":11,"locations":35,"responsibleParty":55,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":11,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Children's Hospital of Fudan University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"intervention group","EXPERIMENTAL",null,[13,14,15],"Behavioral: early bedside rehabilitation","Dietary Supplement: nutrition program","Procedure: tracheotomy",{"label":17,"type":18,"description":11,"interventionNames":11},"control group","NO_INTERVENTION",[20,25,30],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","early bedside rehabilitation","① electrical diaphragm stimulation, ② electrical muscle stimulation, ③ passive limb movement, ④ respiratory rehabilitation.",[9],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"DIETARY_SUPPLEMENT","nutrition program","(1) nutrition department consultation, (2) MDT to develop individualized nutritional pathways, nutrient formulations and use methods, and achieve the target nutritional level within 2 weeks",[9],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":11},"PROCEDURE","tracheotomy","early tracheotomy for special diseases (e.g central nervous system diseases) receiving mechanical ventilation 14-21 days recommended tracheotomy",[9],[36],{"facility":37,"status":38,"city":39,"state":40,"zip":11,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Children's hospital of Fudan University","RECRUITING","Shanghai","Shanghai Municipality","China","CN",{"type":44,"coordinates":45},"Point",[46,47],121.45806,31.22222,{"lat":47,"lon":46},[50],{"name":51,"role":52,"phone":53,"phoneExt":11,"email":54},"Zhengzheng Zhang, doctor","CONTACT","+86 18121445817","6710916@163.com",{"type":56,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100525705","application-of-early-bundle-management-of-mechanical-ventilation-to-prevent-ventilator-dependence-in-children-100525705",false,"NCT06125210","Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children","Inclusion Criteria:\n\n（1）All stable children receiving mechanical ventilation\n\n（1）Stable condition: respiratory rate does not exceed 20% of the basic respiratory rate, PEEP\\\u003C 8. 60%, VIS score\\\u003C 20, there is no hypotension (70mmHg+ age ×2, 70mmHg under one year old), no higher than the P95 of the same sex and age\n\nExclusion Criteria:\n\n1. Status epilepticus\n2. Active intracranial hemorrhage\n3. Intracranial hypertension\n4. Unstable fracture of the spine\n5. Spinal cord injury\n6. There are injuries that affect the implementation of rehabilitation\n7. Acute surgery was performed on the same day.\n8. Body temperature over 40℃\n9. Brain function failure","ALL","28 Days","18 Years",{"count":67,"type":68},150,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a theoretical basis for reasonable intervention of children with mechanical ventilation.\n\nParticipants will receive intensive rehabilitation, nutrition, and tracheotomy at different time periods.\n\nResearchers will compare the control group to see whether it can reduce the incidence of ventilator dependence",[74],"Prolonged Mechanical Ventilation","2026-02-12",{"date":77,"type":78},"2026-02-17","ACTUAL",{"date":80,"type":78},"2024-09-01",{"date":82,"type":68},"2026-12-31",{"name":5,"class":6},1]