[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579962":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":54,"collaborators":10,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":10,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of Iowa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Potential Cystic Fibrosis Carriers",null,"Participants that are identified as potential cystic fibrosis carriers based on aquagenic wrinkling results.",[13],"Procedure: Aquagenic Wrinkling",{"label":15,"type":10,"description":16,"interventionNames":17},"Potential Controls","Participants that are identified as potential controls based on aquagenic wrinkling results.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Aquagenic Wrinkling","Participants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water.",[15,9],[25],{"name":26,"affiliation":5,"role":27},"Philip M Polgreen, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","319-384-6194","philip-polgreen@uiowa.edu",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Shelby L Francis, PhD","319-678-8037","shelby-francis@uiowa.edu",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Iowa City","Iowa","52242","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-91.53017,41.66113,{"lat":49,"lon":48},[52],{"name":53,"role":30,"phone":35,"phoneExt":10,"email":36},"Shelby Francis, PhD",{"type":27,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Philip Polgreen","Professor","100579962","aquagenic-wrinkling-prediction-100579962",false,"NCT06831110","Aquagenic Wrinkling Prediction","Using Aquagenic Wrinkling to Predict CF Carrier State","Inclusion Criteria:\n\n* Interested in participating in other CF Carrier-related research studies.\n\nExclusion Criteria:\n\n* CF patient status\n* Unable to speak English\n* Unable to provide written informed consent\n* Prisoner status\n* An open wound on either hand\n* A tattoo on either hand\n* Missing any portion of either hand\n* Diagnosis of Diabetes\n* Diagnosis of Hyperhidrosis\n* Diagnosis of Raynaud's Disease\n* Diagnosis of Atopic Dermatitis\n* Regularly taking ACE inhibitors or angiotensin receptor blockers",true,"ALL","18 Years","24 Years",{"count":69,"type":70},2000,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status.\n\nParticipants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.",[74,75],"Aquagenic Wrinkling of Palms","Carrier State","2026-06-02",{"date":78,"type":79},"2026-06-04","ACTUAL",{"date":81,"type":79},"2025-03-06",{"date":83,"type":70},"2026-12",{"name":5,"class":6},1]