[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554370":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":63,"collaborators":65,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":24,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":24,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Eye & ENT Hospital of Fudan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"AR training group","EXPERIMENTAL","Dichoptic augmented reality training with dual-pathway (parvocellular pathway and magnocellular pathway) and interocular push-pull paradigms developed based on neural deficits in unilateral amblyopia.",[13],"Other: AR training",{"label":15,"type":16,"description":17,"interventionNames":18},"Patching group","ACTIVE_COMPARATOR","Conventional patching therapy.",[19],"Other: Patching",[21,25],{"type":6,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"AR training",[9],null,{"type":6,"name":26,"description":17,"armGroupLabels":27,"otherNames":24},"Patching",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Wen Wen, MD, PhD","CONTACT","86+(021)34233133","wenweneye@126.com",{"name":35,"role":31,"phone":24,"phoneExt":24,"email":36},"Yulian Zhou, MD","zyl_1208@163.com",[38],{"facility":39,"status":40,"city":41,"state":24,"zip":24,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Eye & ENT Hospital of Fudan University","RECRUITING","Shanghai","China","CN",{"type":45,"coordinates":46},"Point",[47,48],121.45806,31.22222,{"lat":48,"lon":47},[51,53,56,58,61],{"name":30,"role":31,"phone":52,"phoneExt":24,"email":33},"86+(021)34233133‬",{"name":54,"role":55,"phone":24,"phoneExt":24,"email":24},"Wen Wen","PRINCIPAL_INVESTIGATOR",{"name":57,"role":55,"phone":24,"phoneExt":24,"email":24},"Chen Zhao",{"name":59,"role":60,"phone":24,"phoneExt":24,"email":24},"Yulian Zhou","SUB_INVESTIGATOR",{"name":62,"role":60,"phone":24,"phoneExt":24,"email":24},"Rui Liu",{"type":64,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[66,68,70],{"name":67,"class":6},"First Affiliated Hospital of Fujian Medical University",{"name":69,"class":6},"Shanghai Tong Ren Hospital",{"name":71,"class":6},"Jiangsu Provincial People's Hospital","100554370","ar-training-versus-patching-in-unilateral-amblyopia-100554370",false,"NCT06498206","AR Training Versus Patching in Unilateral Amblyopia","Dichoptic Augmented Reality (AR) Training Versus Patching for Unilateral Amblyopia in Children and Adults","Inclusion Criteria:\n\n1. Aged 5-55 years (including 5 years and 55 years);\n2. Best-corrected visual acuity worse than 20\u002F30 but no worse than 20\u002F200 in the amblyopic eye, interocular difference of 2 or more lines, with the better eye within the normal range;\n3. Patients have applied optical refractive correction for more than 3 months;\n4. Ability attend visits and complete the treatment;\n5. Normal binocular alignment including strabismic amblyopia with orthotropia after surgical correction, or intermittent exotropia within a range of -15 to 0 prism diopters measured by the prism cover test.\n\nExclusion Criteria:\n\n1. Organic eye diseases preventing the establishment of good vision (e.g. ptosis, media opacity, nystagmus, paracentral fixation, acute inflammation like keratitis, optic nerve diseases like glaucoma, retinal diseases);\n2. Lesions of the brain preventing the establishment of good vision (e.g. cortical visual impairment);\n3. Implantable electronic device;\n4. A history of ocular surgery (except strabismus surgery) affecting vision (e.g. retinal detachment repair);\n5. A history of ocular trauma affecting vision;\n6. Receiving amblyopia therapy (except wearing glasses) within 2 weeks prior to presentation;\n7. History of epilepsy or mental illness, or cognitive defects;\n8. Currently taking medications or needing to take medications during the study period that may affect vision;\n9. Inability to comply with the treatments or follow-up visits required;\n10. Participation in clinical trials on drugs within 3 months prior to presentation, or clinical trials on other medical devices within 30 days prior to presentation.","ALL","5 Years","55 Years",{"count":83,"type":84},114,"ESTIMATED","INTERVENTIONAL",[87],"NA","This is a multi-center, randomized controlled trial to compare the effectiveness of AR training with patching for the treatment of unilateral amblyopia.\n\nSpecific Aim 1 (Primary): To compare the improvement of visual acuity in the amblyopic eye between AR training and patching for the treatment of unilateral amblyopia.\n\nSpecific Aim 2 (Secondary): To compare the improvement of visual functions between AR training and patching for the treatment of unilateral amblyopia.",[90],"Amblyopia Unilateral",[92,93,26],"Augmented reality training","Dichoptic therapy","2025-04-08",{"date":96,"type":97},"2025-04-10","ACTUAL",{"date":99,"type":97},"2024-08-31",{"date":101,"type":84},"2025-12",{"name":5,"class":6},1]