[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627677":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":30,"locations":34,"responsibleParty":36,"collaborators":34,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":34,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":65,"whyStopped":34,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":34},{"fullName":5,"class":6},"ASL Lecce","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ALL Fixation at 0 Degrees of Knee Flexion","ACTIVE_COMPARATOR","Participants undergoing combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) reconstruction in which the ALL graft is fixed with the knee in full extension (0 degrees) during surgery.",[13],"Procedure: anterolateral ligament reconstruction",{"label":15,"type":10,"description":16,"interventionNames":17},"ALL Fixation at 30 Degrees of Knee Flexion","Participants undergoing combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) reconstruction in which the ALL graft is fixed with the knee flexed at 30 degrees during surgery.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","anterolateral ligament reconstruction","The intervention consists of a standardized combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) reconstruction performed using anatomical single-bundle ACL reconstruction and anatomical ALL reconstruction. The surgical technique, graft selection, tunnel placement, fixation devices, and postoperative rehabilitation protocol are identical in both study arms.\n\nThe only variable distinguishing the interventions is the knee flexion angle at the time of femoral fixation of the ALL graft. In one group, the ALL graft is tensioned and fixed with the knee in full extension (0 degrees). In the other group, the ALL graft is tensioned and fixed with the knee positioned at 30 degrees of flexion. No intraoperative measurements of graft tension are performed, and fixation is carried out according to a predefined standardized protocol.\n\nAll procedures are performed by experienced surgeons using the same surgical landmarks for graft placement, with the intent of isolating the effect",[9,15],[25],"acl + all reconstruction",[27],{"name":28,"affiliation":5,"role":29},"Jacopo Conteduca, MD","STUDY_DIRECTOR",[31],{"name":28,"role":32,"phone":33,"phoneExt":34,"email":35},"CONTACT","0039 3332280645",null,"CONTEDUCA85@GMAIL.COM",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Jacopo Conteduca","MD","100627677","are-clinical-outcomes-unchanged-by-all-fixation-at-0-or-30-of-knee-flexion-in-combined-acl-all-reconstruction-despite-numerous-technical-descriptions-of-anterolateral-procedures-there-is-limited-knowledge-regarding-the-effect-of-knee-flexion-angle-during-graft-fixation-100627677",false,"NCT07451743","Are Clinical Outcomes Unchanged by ALL Fixation at 0° or 30° of Knee Flexion in Combined ACL-ALL Reconstruction? Despite Numerous Technical Descriptions of Anterolateral Procedures, There is Limited Knowledge Regarding the Effect of Knee Flexion Angle During Graft Fixation.","Are Clinical Outcomes Unchanged by ALL Fixation at 0° or 30° of Knee Flexion in Combined ACL-ALL Reconstruction?","ACL ALL","inclusion Criteria:\n\n* Patients with a unilateral anterior cruciate ligament (ACL) rupture confirmed by clinical examination and magnetic resonance imaging (MRI)\n* Persistent knee instability despite conservative treatment\n* Ability to understand the study procedures and provide written informed consent\n* Willingness to comply with the postoperative rehabilitation protocol and follow-up schedule\n\nExclusion Criteria:\n\n* Previous ACL reconstruction or revision surgery on the affected knee\n* Bilateral ACL injuries\n* Concomitant knee osteoarthritis greater than Kellgren-Lawrence grade 1\n* Concomitant ligament injuries requiring additional surgical procedures (except meniscal treatment)\n* History of neurological, vestibular, or visual disorders affecting balance or gait\n* Inflammatory joint disease or systemic musculoskeletal disorders\n* Incomplete baseline clinical data\n* Inability to complete patient-reported outcome questionnaires or attend follow-up visits","ALL","16 Years","45 Years",{"count":52,"type":53},100,"ESTIMATED","INTERVENTIONAL",[56],"NA","This study evaluates whether the knee flexion angle used during fixation of the anterolateral ligament (ALL) affects clinical outcomes in patients undergoing combined anterior cruciate ligament (ACL) and ALL reconstruction.\n\nCombined ACL and ALL reconstruction is increasingly used to improve rotational knee stability and reduce the risk of graft failure after ACL injury. However, the optimal knee position for fixing the ALL graft during surgery remains unclear. In this study, patients were treated with ALL fixation performed either in full knee extension (0 degrees) or at 30 degrees of knee flexion.\n\nClinical outcomes, knee stability, patient-reported function, and graft failure rates were compared between the two groups at a minimum follow-up of two years. Outcomes were assessed using validated questionnaires, clinical examinations, and objective measurements of knee stability.\n\nThe study aims to determine whether the knee flexion angle at the time of ALL fixation influences postoperative function, stability, or complication rates, and to provide clinical evidence to guide surgical technique in combined ACL and ALL reconstruction.",[59],"Anterior Cruciate Ligament Rupture",[61,62,63,64],"acl","all","antepor cruciate ligament","anterolateral ligament","NOT_YET_RECRUITING","2026-03-02",{"date":68,"type":69},"2026-03-05","ACTUAL",{"date":71,"type":53},"2026-03-30",{"date":73,"type":53},"2029-01",{"name":5,"class":6}]