[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582020":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":11,"locations":21,"responsibleParty":40,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"The University of Texas at Arlington","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":10},"Older Adults",null,[12,17],{"name":13,"role":14,"phone":15,"phoneExt":10,"email":16},"Michael Nelson, PhD","CONTACT","8175130383","michael.nelson3@uta.edu",{"name":18,"role":14,"phone":19,"phoneExt":10,"email":20},"Rajvi Shah, MPH","2147557343","rajvi.shah@uta.edu",[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"University of Texas Arlington","RECRUITING","Arlington","Texas","76019","United States","US",{"type":31,"coordinates":32},"Point",[33,34],-97.10807,32.73569,{"lat":34,"lon":33},[37,38],{"name":18,"role":14,"phone":19,"phoneExt":10,"email":20},{"name":13,"role":39,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":39,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Michael Nelson","Associate Professor","100582020","arlington-aging-study-100582020",false,"NCT06857877","Arlington Aging Study","Arlington Study of Healthy Aging","Inclusion Criteria:\n\nPhase 1: Young healthy men and women between 18 - 30 years of age, and older men and women between 50 - 80 years of age.\n\nPhase 2: Men and women living in Tarrant County, Texas, between 50 - 85 years of age. In addition, the investigators will study up to 120 younger men and women, between 18-30 years of age, equally divided by race\u002Fethnicity (same as above) and sex, to serve as reference controls.\n\nExclusion Criteria:\n\nPhase 1: Clinical diagnosis of dementia; major depression (diagnosed by a physician), visual or auditory impairments that preclude neuropsychological testing or otherwise jeopardize the health and wellbeing of the participant during testing, non-ambulatory status (i.e. less than 10 m without mobility aid), shortness of breath while performing normal activities of daily living (walking through grocery store), body mass index greater than 45 kg\u002Fm2, heart failure or cardiomyopathy, acute coronary syndrome, primary valvular heart disease, severe gait disorder due to musculoskeletal disease or neurological motor deficit (e.g. severe osteoarthritis, lower limb amputation, Parkinson's disease, major stroke with motor sequelae); daily consumption of more than two alcoholic beverages; current treatment for cancer, and estimated life expectancy less than 4 years. Inclusion\u002Fexclusion will be verified using the demographics and medical history.\n\nPhase 2: Clinical diagnosis of dementia; major depression (diagnosed by a physician), visual or auditory impairments that preclude neuropsychological testing or otherwise jeopardize the health and wellbeing of the participant during testing, non-ambulatory status (i.e. less than 10 m without mobility aid), shortness of breath while performing normal activities of daily living (walking through grocery store), body mass index greater than 45 kg\u002Fm2, heart failure or cardiomyopathy, acute coronary syndrome, primary valvular heart disease, severe gait disorder due to musculoskeletal disease or neurological motor deficit (e.g. severe osteoarthritis, lower limb amputation, Parkinson's disease, major stroke with motor sequelae), daily consumption of more than two alcoholic beverages; current treatment for cancer, and estimated life expectancy less than 4 years. Inclusion\u002Fexclusion will be verified using the demographics and medical history.",true,"ALL","18 Years","85 Years",{"count":55,"type":56},770,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the mechanisms causing functional decline with age, using magnetic resonance imaging, exercise science, integrative physiology, neuroscience, and remote monitoring.\n\nSpecific aims include:\n\nAim 1: Advance knowledge of the biology of aging and its impact on the prevention, progression, and prognosis of disease and disability.\n\nAim 2: Determine the effects of personal and societal factors on aging.\n\nAim 3: Examine the influence of racial\u002Fethnic and sex differences on the biology of aging and its impact on the prevention, progression, and prognosis of disease and disability.",[60],"Aging",[60,62,63,64,65],"MRI","Cognitive Function","Exercise Science","Remote Monitoring","2026-04-20",{"date":68,"type":69},"2026-04-23","ACTUAL",{"date":71,"type":69},"2024-09-01",{"date":73,"type":56},"2030-12-31",{"name":5,"class":6},1]