[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494935":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":62,"collaborators":28,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":28,"enrollmentInfo":74,"targetDuration":28,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":28,"overallStatus":45,"whyStopped":28,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy Volunteers","EXPERIMENTAL","N = 10, who do not use contact lenses or eye glasses and have a recent evaluation of vision 10\u002F10 ta participate in the repeatability study.",[13],"Diagnostic Test: MRI perfusion imaging using ASL's non-invasive technique",{"label":15,"type":10,"description":16,"interventionNames":17},"Chronic","N = 30 (10 patients with thyroid associated orbitopathy (TAO), 10 patients with inflammatory optic neuropathy (ION), 10 patients with ischemic neuropathy), all chronic patients followed in ophthalmology consultation, enlightened volunteers ta participate in the study, and presenting a decrease in residual visual acuity entering the TAO, inflammatory or ischemic frameworks.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Acute","N = 30 (10 patients with TAO, 10 patients with ION, 10 patients with ischemic neuropathy) all patients seen in the acute phase in ophthalmology consultation who will accept participation in the study, knowing the constraint of repeating the examination in the chronic phase.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DIAGNOSTIC_TEST","MRI perfusion imaging using ASL's non-invasive technique","Patients will undergo through an MRI-scan using the ASL MRI sequence, as described per protocol.",[19,15,9],null,[30],{"name":31,"affiliation":5,"role":32},"Idil Günes-Tatar, MD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":28,"email":37},"CONTACT","+32.276442544","idil.gunes@saintluc.uclouvain.be",{"name":39,"role":35,"phone":40,"phoneExt":28,"email":41},"Thierry Duprez, MD","+32.276442919","thierry.duprez@saintluc.uclouvain.be",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Cliniques Universitaires Saint Luc","RECRUITING","Brussels","Brussels Capital","1200","Belgium","BE",{"type":52,"coordinates":53},"Point",[54,55],4.34878,50.85045,{"lat":55,"lon":54},[58],{"name":59,"role":35,"phone":60,"phoneExt":28,"email":61},"Perrine Triqueneaux","003227642935","perrine.triqueneaux@uclouvain.be",{"type":63,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100494935","arterial-spin-labeling-mri-for-assessing-blood-perfusion-in-the-human-eye-repeatability-study-and-clinical-application-100494935",false,"NCT05724641","Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application","PerfRet","Inclusion criteria:\n\n* Carrier of target pathologies: TAO optic neuropathy, inflammatory optic neuropathy, ischemic optic neuropathy.\n* no cardiovascular risk factors or other ophthalmological pathology\n* adhere to the study protocol after reading the patient information document\n* signe the informed consent form to participate in the study\n* do not have any contraindications to an MRI examination\n\nExclusion criteria\n\n* Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear implant,…)\n* Severe claustrophobia",true,"ALL","18 Years",{"count":75,"type":76},70,"ESTIMATED","INTERVENTIONAL",[79],"NA","The MRI perfusion imaging using arterial spin labeling (ASL)'s non-invasive technique (i.e. without injection of contrast medium) allows, thanks to recent technological improvement of the spatial resolution, measuring several perfusion parameter of the retinal tissue such as the regional Blood Flow (rBF) or the cerebral blood flow (cBF) expressed in ml\u002F100g\u002Fmin. Reliable application of ASL thus requires the precision and specificity of the MRI protocol to be tested.",[82],"Retinal Diseases","2025-05-13",{"date":85,"type":86},"2025-05-16","ACTUAL",{"date":88,"type":86},"2023-01-10",{"date":90,"type":76},"2026-06-30",{"name":5,"class":6},1]