[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633093":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":28,"responsibleParty":61,"collaborators":10,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":77,"studyType":78,"phases":10,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Istanbul Mehmet Akif Ersoy Educational and Training Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients with CTEPH",null,[12],"Procedure: Balloon Pulmonary Angioplasty",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"PROCEDURE","Balloon Pulmonary Angioplasty","Balloon Pulmonary Angioplasty as per procedural standards",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Umit Bulut, MD","CONTACT","+90(212) 692 20 00","umit.bulut@saglik.gov.tr",{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},"Ahmet Tas, MD PhD","ahmettas.cor@gmail.com",[29],{"facility":5,"status":30,"city":31,"state":10,"zip":32,"country":33,"countryCode":10,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"RECRUITING","Istanbul","34303","Turkey (Türkiye)",{"type":35,"coordinates":36},"Point",[37,38],28.94966,41.01384,{"lat":38,"lon":37},[41,42,43,45,46,49,51,53,55,57,59],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},{"name":21,"role":44,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":26,"role":44,"phone":10,"phoneExt":10,"email":10},{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Begum Uygur, Ass. Prof. MD","SUB_INVESTIGATOR",{"name":50,"role":48,"phone":10,"phoneExt":10,"email":10},"Gizemnur Coskun, MD",{"name":52,"role":48,"phone":10,"phoneExt":10,"email":10},"Mustafa Batcioglu, MD",{"name":54,"role":48,"phone":10,"phoneExt":10,"email":10},"Dogukan Salduz, MD",{"name":56,"role":48,"phone":10,"phoneExt":10,"email":10},"Sahin Muradov, MD",{"name":58,"role":48,"phone":10,"phoneExt":10,"email":10},"Mehmet Erturk, Professor MD",{"name":60,"role":48,"phone":10,"phoneExt":10,"email":10},"Yaren Alan, MD",{"type":44,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Umit Bulut","MD","100633093","arterial-wave-energy-flux-and-multidimensional-recovery-in-patients-with-chronic-thromboembolic-pulmonary-hypertension-undergoing-balloon-pulmonary-angioplasty-100633093",false,"NCT07522203","Arterial Wave Energy Flux and Multidimensional Recovery in Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Balloon Pulmonary Angioplasty","WE FIX BPA","Inclusion Criteria:\n\n* Age 18-85 years.\n\nConfirmed diagnosis of CTEPH by a multidisciplinary CTEPH team and deemed eligible for BPA.\n\nHemodynamics compatible with pre-capillary PH according to current guidelines, as assessed by RHC (Right Heart Catheterization).\n\nTechnically inoperable CTEPH or persistent\u002Frecurrent PH following PEA (Pulmonary Endarterectomy).\n\nWritten informed consent.\n\nExclusion Criteria:\n\n* Predominant diagnosis of PH other than CTEPH or concomitant severe parenchymal lung disease.\n\nActive infection, uncontrolled systemic disease, active malignancy, or life expectancy \\\u003C 12 months.\n\nPregnant or lactating patients.\n\nAdvanced renal failure (e.g., eGFR \\\u003C 30 \\\\text{ mL\u002Fmin\u002F1.73 m\\^2}) or contraindications to contrast media (per institutional routine).\n\nInadequate image quality precluding reliable echocardiographic analysis.\n\nPressure tracings with significant artifacts hindering analysis or uncontrolled arrhythmia (e.g., atrial fibrillation with rapid ventricular response).\n\nDecompensated or hemodynamically unstable patients.\n\nAny other condition deemed clinically unsuitable by the investigator.","ALL","18 Years","85 Years",{"count":75,"type":76},70,"ESTIMATED","12 Months","OBSERVATIONAL","The goal of this observational study is to learn if advanced heart pressure wave analysis (called WIA and REPA) can help track and predict clinical improvement in adults (aged 18-85) with Chronic Thromboembolic Pulmonary Hypertension (CTEPH) who are undergoing Balloon Pulmonary Angioplasty (BPA).\n\nThe main questions it aims to answer are:\n\nDo changes in these advanced heart pressure wave patterns relate to improvements in a patient's walking distance, heart function, and overall quality of life after BPA treatment?\n\nAre these new measurements more effective than standard heart pressure tests at showing how much a patient has truly improved?\n\nParticipants will:\n\nUndergo standard Balloon Pulmonary Angioplasty (BPA) sessions as part of their regular medical care for CTEPH.\n\nHave their heart pressure waves recorded through a catheter during the routine BPA procedure (this does not require any extra surgical steps).\n\nComplete walking tests (6-minute walk test), blood tests, and heart ultrasounds (echocardiography) before starting the treatment and after it is completed.\n\nFill out short surveys regarding their daily physical activity and quality of life.",[81,82],"CTEPH","Pulmonary Hypertension (PH)",[84,85,16],"Arterial Wave Energy","Hemodynamics","2026-04-03",{"date":88,"type":89},"2026-04-13","ACTUAL",{"date":91,"type":89},"2026-03-10",{"date":93,"type":76},"2028-05-01",{"name":5,"class":6},1]