[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638314":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":28,"locations":34,"responsibleParty":48,"collaborators":11,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":11,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":11,"enrollmentInfo":61,"targetDuration":11,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":74,"overallStatus":78,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Arthroscopic lysis and lavage","ACTIVE_COMPARATOR",null,[13],"Procedure: Arthroscopic lysis and lavage",{"label":15,"type":16,"description":11,"interventionNames":17},"Arthroscopic lysis and lavage with single intra-articular hyaluronic acid injection","EXPERIMENTAL",[18],"Procedure: arthroscopic lysis and lavage with intra-articular injection of hyaluronic acid",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"PROCEDURE","Arthroscopic lysis and lavage without intra-articular hyaluronic acid injection",[9],{"type":21,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"arthroscopic lysis and lavage with intra-articular injection of hyaluronic acid","Arthroscopic lysis and lavage followed by intra-articular injection of hyaluronic acid",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},"Eshraq Ahmed ElMetwally","CONTACT","+201287472001","eshraq.elmetwally@dentistry.cu.edu.eg",[35],{"facility":36,"status":11,"city":37,"state":11,"zip":11,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Faculty of Dentistry, Cairo University","Cairo","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.24967,30.06263,{"lat":44,"lon":43},[47],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Eshraq Ahmed","Dr","100638314","arthroscopic-lysis-and-lavage-with-and-without-intra-articular-injection-of-hyaluronic-acid-in-patients-with-ddwor-in-tmj-100638314",false,"NCT07614932","Arthroscopic Lysis and Lavage With and Without Intra-articular Injection of Hyaluronic Acid in Patients With DDwoR in TMJ","Assessment of Arthroscopic Lysis and Lavage With And Without Intra-Articular Injection of Hyaluronic Acid in the Management of Patients With Disc Displacement Without Reduction: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Adults above 18 years old.\n2. Diagnosis of Disc Displacement Without Reduction (DDWOR) with limited mouth : eitherunilateral or bilateral based on the DC\u002FTMD and confirmed with MRI\n3. History of unsuccessful conservative treatment such as physical therapy, occlusal splints,or medications (e.g., NSAIDs, muscle relaxants) for at least 3 months.\n4. Patients must sign the informed consent, understand the study procedures and potential risks, accept to volunteer in the study and be available to attend the follow-up visits.\n\nExclusion Criteria:\n\n1. Degenerative Temporomandibular Joint Disorders (e.g., osteoarthritis, rheumatoid arthritis).\n2. History of prior TMJ surgery (e.g., joint replacement, previous arthroscopy).\n3. Severe Systemic Conditions (e.g., cardiovascular disease, autoimmune disorders, uncontrolled diabetes).\n4. Active joint infection, acute inflammation, or presence of any condition that may increase the risk of complications from arthroscopic surgery or injections (e.g., local infection, uncontrolled bleeding disorders).\n5. Pregnancy or Breastfeeding.\n6. Patients with severe Psychological Conditions (e.g., severe depression, psychosis, myofascial pain disorder) or dental related pain will be identified at the initial assessment and referred for appropriate psychological, behavioural, or dental management prior to inclusion in the study.","ALL","18 Years",{"count":62,"type":63},52,"ESTIMATED","INTERVENTIONAL",[66],"NA","The study aims to assess the outcomes of arthroscopic lysis and lavage procedure with and without single intra-articular injection of hyaluronic acid in managing patients with anterior disc displacement without reduction.\n\nThe research question that this study will answer is:\n\nDoes arthroscopic lysis and lavage combined with hyaluronic acid provide better outcomes in terms of pain intensity and maximum mouth opening compared to arthroscopic lysis and lavage alone?",[69,70,71,72,73],"TMJ Disc Disorder","Temporomandibular Joint Disc Displacement, Without Reduction","TMD\u002FOrofacial Pain","Temporomandibular Disorder","TMJ Closed Lock",[75,76,77],"TMJ arthroscopy","TMJ arthroscopic lysis and lavage","Anterior Disc Displacement without reduction","NOT_YET_RECRUITING","2026-05-22",{"date":81,"type":82},"2026-05-29","ACTUAL",{"date":84,"type":63},"2026-05",{"date":86,"type":63},"2027-01",{"name":5,"class":6},1]