[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626171":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":31,"centralContacts":31,"locations":32,"responsibleParty":51,"collaborators":31,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":31,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":31,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":35,"whyStopped":31,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"October University for Modern Sciences and Arts","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Human-Designed Fixed Dental Prosthesis (Conventional CAD)","Fixed dental prostheses will be designed manually using conventional CAD software by experienced dental professionals based on occlusal anatomy and patient-specific scan data. The designs will serve as the control comparator to evaluate accuracy against AI-generated designs using 3D superimposition analysis.",[12],"Other: Conventional CAD-Based Fixed Dental Prosthesis Design",{"label":14,"type":6,"description":15,"interventionNames":16},"AI-Designed Fixed Dental Prosthesis","Fixed dental prostheses will be automatically generated using an artificial intelligence-based design system. The AI model will be trained, validated, and tested using occlusal scan datasets and historical human-designed prostheses. The generated designs will be evaluated for accuracy using 3D superimposition and Intersection over Union (IoU) analysis.",[17],"Other: Artificial Intelligence-Based Fixed Dental Prosthesis Design",[19,25],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Conventional CAD-Based Fixed Dental Prosthesis Design","Fixed dental prostheses will be digitally designed using conventional computer-aided design (CAD) software by experienced dental professionals. Designs will be based on occlusal anatomy and patient-specific intraoral scan data. These manually generated digital designs will serve as the comparator for evaluating accuracy against AI-generated designs using 3D superimposition and quantitative accuracy analysis.",[9],[24],"Human Digital Design",{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Artificial Intelligence-Based Fixed Dental Prosthesis Design","An artificial intelligence-based automated design system will generate fixed dental prosthesis designs using deep learning algorithms. The AI model will be trained (60%), validated (10%), and tested (30%) on occlusal scan datasets and historical human-designed prostheses. Generated designs will be evaluated for accuracy and marginal precision using 3D superimposition and Intersection over Union (IoU) analysis.",[14],[30],"AI Crown Design Model",null,[33],{"facility":34,"status":35,"city":36,"state":31,"zip":31,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"MSA University","RECRUITING","Giza","Egypt","EG",{"type":40,"coordinates":41},"Point",[42,43],31.20861,30.00944,{"lat":43,"lon":42},[46],{"name":47,"role":48,"phone":49,"phoneExt":31,"email":50},"Modern Sciences and Arts MSA October University for Modern Sciences and Arts","CONTACT","002-0216672","info@msa.edu.eg",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Tarek Adham Saad Ahmed El-Shammaa","Master student of Prosthodontics","100626171","artificial-intelligence-versus-conventional-digital-design-for-fixed-dental-prosthesis-100626171",false,"NCT07432165","Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis","Accuracy Assessment of Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis: (An Invitro Study)","Inclusion Criteria:\n\n* Adults aged 18-65 years Patients with a damaged tooth requiring a fixed dental prosthesis Available digital intraoral scans Adequate occlusal anatomy for analysis of opposing teeth\n\nExclusion Criteria:\n\n* Incomplete or poor-quality digital scans Severe occlusal abnormalities affecting analysis Patients outside the specified age range","ALL","18 Years","65 Years",{"count":66,"type":67},1000,"ESTIMATED","INTERVENTIONAL",[70],"NA","This in vitro study aims to evaluate the accuracy of an Artificial Intelligence (AI)-based automatic design system for fixed dental prosthesis (FDP) compared with conventional computer-aided design (CAD) software. Digital scans of teeth requiring fixed dental prosthesis will be collected and used to generate prosthetic designs using two approaches: human-designed CAD restorations and AI-generated restorations.\n\nThe primary outcome is design accuracy assessed using 3D superimposition and Intersection over Union (IOU) percentage. Secondary outcomes include margin detection performance measured using F1 score, precision, and recall. A total sample size of 438 scans will be analyzed.\n\nThe study will determine whether AI-generated prosthesis designs demonstrate comparable accuracy to conventional digital designs.",[73],"Accuracy of Artificial Intelligence in Fixed Dental Prosthesis Design",[75,76,77,78,79,80,81,82],"Artificial Intelligence","CAD\u002FCAM","Fixed Dental Prosthesis","Dental Crown Design","3D Superimposition","Deep Learning","Generative Adversarial Network (GAN)","Prosthodontics","2026-02-19",{"date":85,"type":86},"2026-02-25","ACTUAL",{"date":88,"type":86},"2025-06-15",{"date":90,"type":67},"2026-06-17",{"name":5,"class":6},1]