[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615908":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":42,"collaborators":46,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Corporacion Parc Tauli","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Critical care patient",null,"Critical care patients with their blood pressure invasively monitored through an arterial line",[13],"Other: Passive Leg Raising maneuver",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Passive Leg Raising maneuver","The PLR will be performed using automatic bed adjustment: Starting from a semi-recumbent position, the lower limbs will be elevated to a 45° angle while the trunk will be moved from semi-recumbent to supine. After three minutes, subjects will be returned to the initial semi-recumbent position.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Jaume Mesquida Senior Clinical Researcher, MD","CONTACT","+34 616722287","jmesquida@tauli.cat",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Parc Taulí Hospital Universitari","RECRUITING","Sabadell","Spain\u002F Barcelona","08208","Spain","ES",{"type":35,"coordinates":36},"Point",[37,38],2.10942,41.54329,{"lat":38,"lon":37},[41],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Jaume Mesquida","Senior Clinical Researcher",[47],{"name":48,"class":49},"Institut de Ciències Fotòniques (ICFO)","UNKNOWN","100615908","assessing-fluid-responsiveness-using-non-invasive-hybrid-diffuse-optics-on-peripheral-muscle-100615908",false,"NCT07298720","Assessing Fluid-responsiveness Using Non-invasive Hybrid Diffuse Optics on Peripheral Muscle","hDOS-CO","Inclusion Criteria:\n\n* Invasive blood pressure monitoring through an arterial line\n\nExclusion Criteria:\n\n* Patients with suspected pregnancy\n* Intra-abdominal hypertension\n* Elevated intracranial pressure","ALL","18 Years",{"count":60,"type":61},200,"ESTIMATED","OBSERVATIONAL","Proof-of-concept observational study including ICU patients undergoing a PLR maneuver. Local microvasculature will be assessed with the hDOS platform on the brachioradialis muscle, deriving the microvascular blood flow index (BFI) and tissue oxygen saturation (StO2). CO will be assessed via an invasive hemodynamic monitor based on pulse waveform analysis through the patient's arterial line. The correlation over time between CO and microvascular parameters, and the ability of microvascular variables for predicting a positive CO response (increase \\> 10%) will be assessed.",[65],"Critical Illness",[67,68,69,70],"Fluid-responsiveness","Hemodynamic monitoring","Preload-responsiveness","Cardiac output","2026-03-16",{"date":73,"type":74},"2026-03-18","ACTUAL",{"date":76,"type":74},"2025-01-07",{"date":78,"type":61},"2027-01-01",{"name":5,"class":6},1]