[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565230":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":46,"responsibleParty":110,"collaborators":113,"id":126,"slug":127,"hasResults":128,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":128,"sex":134,"minAge":135,"maxAge":25,"enrollmentInfo":136,"targetDuration":25,"studyType":139,"phases":140,"briefSummary":142,"conditions":143,"keywords":147,"overallStatus":49,"whyStopped":25,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":158},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Concealed Control Intervention","ACTIVE_COMPARATOR","Participants receive eight \\~40 minute sessions (one per week) with a therapist\u002Fhealth coach. Specific information regarding the nature of the interventions is withheld to protect the scientific integrity of the study design.",[13,14],"Other: Treatment As Usual","Behavioral: Active Comparator",{"label":16,"type":17,"description":11,"interventionNames":18},"Active Condition","EXPERIMENTAL",[13,19],"Behavioral: Active Condition",[21,26,29],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Treatment As Usual","In this trial, all participants will have depression symptoms and will be receiving TAU from their own doctors.",[16,9],null,{"type":27,"name":16,"description":11,"armGroupLabels":28,"otherNames":25},"BEHAVIORAL",[16],{"type":27,"name":30,"description":11,"armGroupLabels":31,"otherNames":25},"Active Comparator",[9],[33],{"name":34,"affiliation":5,"role":35},"Stephen F Smagula, Ph.D","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},"Sara Sellars, M.A","CONTACT","412-246-5963","alberts3@upmc.edu",{"name":43,"role":39,"phone":44,"phoneExt":25,"email":45},"Stephen Smagula, Ph.D","412-246-6674","smagulasf@upmc.edu",[47,74,95],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"The Regents of the University of California, Los Angeles","RECRUITING","Los Angeles","California","90095","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-118.24368,34.05223,{"lat":59,"lon":58},[62,66,70,72],{"name":63,"role":39,"phone":64,"phoneExt":25,"email":65},"Michael Irwin, PhD","310-825-8281","mirwin1@ucla.edu",{"name":67,"role":39,"phone":68,"phoneExt":25,"email":69},"Jennifer Kruse, PhD","310-206-8095","jkruse@mednet.ucla.edu",{"name":71,"role":35,"phone":25,"phoneExt":25,"email":25},"Michael Iriwn, PhD",{"name":67,"role":73,"phone":25,"phoneExt":25,"email":25},"SUB_INVESTIGATOR",{"facility":75,"status":49,"city":76,"state":77,"zip":78,"country":53,"countryCode":54,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Augusta University","Augusta","Georgia","30912",{"type":56,"coordinates":80},[81,82],-81.97484,33.47097,{"lat":82,"lon":81},[85,89,93,94],{"name":86,"role":39,"phone":87,"phoneExt":25,"email":88},"William McCall, PhD","716-721-6719","wmccall@augusta.edu",{"name":90,"role":39,"phone":91,"phoneExt":25,"email":92},"Jessica Britt-Thomas, PhD","706-721-3141","jebritt@augusta.edu",{"name":86,"role":35,"phone":25,"phoneExt":25,"email":25},{"name":90,"role":73,"phone":25,"phoneExt":25,"email":25},{"facility":5,"status":49,"city":96,"state":97,"zip":98,"country":53,"countryCode":54,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Pittsburgh","Pennsylvania","15213",{"type":56,"coordinates":100},[101,102],-79.99589,40.44062,{"lat":102,"lon":101},[105,106,108],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},{"name":107,"role":35,"phone":25,"phoneExt":25,"email":25},"Stephen F Smagula, PhD",{"name":109,"role":73,"phone":25,"phoneExt":25,"email":25},"Daniel J Buysse, MD",{"type":35,"investigatorFullName":111,"investigatorTitle":112,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Stephen Smagula","Associate Professor of Psychiatry",[114,116,118,120,121,124],{"name":115,"class":6},"Emory University",{"name":117,"class":6},"University of California, Berkeley",{"name":119,"class":6},"University of California, Los Angeles",{"name":75,"class":6},{"name":122,"class":123},"National Institutes of Health (NIH)","NIH",{"name":125,"class":123},"National Institute of Mental Health (NIMH)","100565230","assessing-improvements-in-mood-and-sleep-trial-100565230",false,"NCT06639477","Assessing Improvements in Mood and Sleep Trial","Multi-site Randomized Controlled Trial Comparing the Efficacy of Behavioral Approaches to Improve Mood and Sleep in Adults","AIMS","Inclusion Criteria:\n\n* Age 55 Years and older\n* Patient Health Questionnaire -9 score of 10 or higher\n* Past month Scale for Suicide Ideation score of 3 or higher OR any history of suicide attempt\n* PROMIS Sleep Disturbance or impairment scale t-scores of 55 or higher\n* Pharmacotherapy for depression meeting minimum adequate dose level as defined by FDA approval documents for at least 4 weeks.\n\nExclusion Criteria:\n\n* Active suicide planning with intent or clinical judgement that suicide risk is too high for outpatient treatment OR being currently treated at an inpatient unit.\n* Bipolar disorder\n* Psychotic disorder\n* Borderline personality disorder.\n* Active Cognitive\u002FBehavioral Therapy (e.g., CBT-I), current or upcoming esketamine (ketamine) treatment, or active phase of ECT\u002FTMS treatment course.\n* Illness with life expectancy of less than 1 year or plans to leave the study area\n* Incapacity to consent\u002Fdementia diagnosis\n* Active substance use disorder of at least moderate severity\n* Active night-shift work\n* Any physical, mental, or neurological condition that would make participation in the study, including either treatment arm, unsafe or infeasible.","ALL","55 Years",{"count":137,"type":138},420,"ESTIMATED","INTERVENTIONAL",[141],"NA","This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt). Our goal is evaluate which of two different approaches works best to improve things like trouble sleeping, bad moods, and any suicidality.\n\nParticipants will complete diagnostic interviews, self-report scales, and wear an actigraphy device for the 8 weeks starting at the baseline visit.",[144,145,146],"Depression","Suicidality","Sleep",[148,144],"Older Adults","2026-05-15",{"date":151,"type":152},"2026-05-19","ACTUAL",{"date":154,"type":152},"2025-05-20",{"date":156,"type":138},"2030-08",{"name":5,"class":6},3]