[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617963":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":70,"collaborators":74,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":25,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":25,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MB-Spirit","EXPERIMENTAL","8-week online course that combines mindfulness with character strengths to promote well-being",[13],"Behavioral: MB-Spirit",{"label":15,"type":16,"description":17,"interventionNames":18},"Strong Behaviors for Stress Reduction","ACTIVE_COMPARATOR","self-paced program. Participants receive materials once a week to complete at their own pace",[19],"Behavioral: Strong Behaviors for Stress Reduction",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","8-week online course that uses character strengths and mindfulness to promote well-being. Based on 3-part model of spirituality",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Self-paced",[15],[30],{"name":31,"affiliation":5,"role":32},"Sara Lazar, PhD","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Study Staff","CONTACT","617-415-8813","slazar@mgh.harvard.edu",{"name":40,"role":36,"phone":25,"phoneExt":25,"email":41},"Staff","stressreduction@partners.org",[43,61],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"149 13th St","RECRUITING","Boston","Massachusetts","02129","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-71.05977,42.35843,{"lat":55,"lon":54},[58],{"name":59,"role":36,"phone":60,"phoneExt":25,"email":38},"Research Coordinator","617-724-7108",{"facility":62,"status":63,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":64,"geoPoint":66,"contacts":67},"Charlestown Navy Yard Campus","NOT_YET_RECRUITING",{"type":52,"coordinates":65},[54,55],{"lat":55,"lon":54},[68],{"name":31,"role":36,"phone":69,"phoneExt":25,"email":38},"6177247108",{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Sara W Lazar","Associate Research Scientist",[75],{"name":76,"class":6},"Harvard Medical School (HMS and HSDM)","100617963","assessing-mb-spirit-for-psychological-well-being-100617963",false,"NCT07325448","Assessing MB-Spirit for Psychological Well-being","Assessing MB-Spirit: A Novel Intervention for Promoting Spiritual Development and Psychological Well-being","Inclusion Criteria:\n\n* Understands English\n* Able to attend all 8 classes\n* Able to travel to Boston for MRI scans\n\nExclusion Criteria:\n\n* claustrophobia, pregnancy, head trauma, metallic implants or devices contraindicating MRI, left-handed, conditions that alter cerebral blood flow or metabolism (e.g. stroke), current use of psychotropic medications, lifetime history of suicidality, homicidally, self-destructive acts, schizophrenia or psychosis.",true,"ALL","18 Years","50 Years",{"count":89,"type":90},44,"ESTIMATED","INTERVENTIONAL",[93],"NA","The goal of this clinical trial is to test two new behavioral interventions designed to reduce stress and improve spiritual well-being in stressed adults. The main questions it aims to answer are:\n\n1. Can the program decrease stress and improve spiritual well-being?\n2. What brain changes accompany participation in the programs?\n\nParticipants will:\n\n1. Be randomized to either a live online course that meets for 90 minutes every week for 8-weeks, or to a self-paced program. In the self-paced program, participants will receive materials once a week and can work through them at their own pace. Both programs are designed to decrease stress and improve well-being.\n2. Complete questionnaires before and after the course.\n3. Complete and interview before and after the course.\n4. A subset of people will be randomized to complete an MRI scan of their brain before and after the course.\n\nParticipants will be randomized to either take the course right away, or be put on a wait-list. Those on the wait-list will undergo the testing at 2 timepoints before they start the program.",[96],"Stress",[98,99,100,101],"stress","MRI","spirituality","well-being","2026-06-09",{"date":104,"type":105},"2026-06-11","ACTUAL",{"date":107,"type":105},"2026-03-15",{"date":109,"type":90},"2026-11",{"name":72,"class":6},2]