[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583112":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":15,"collaborators":10,"id":19,"slug":20,"hasResults":21,"nctId":22,"briefTitle":23,"officialTitle":24,"acronym":10,"eligibilityCriteria":25,"healthyVolunteers":26,"sex":27,"minAge":28,"maxAge":10,"enrollmentInfo":29,"targetDuration":32,"studyType":33,"phases":10,"briefSummary":34,"conditions":35,"keywords":38,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"SLE Patients",null,"This group consists of 70 adult patients diagnosed with systemic lupus erythematosus (SLE) according to the 2019 ACR\u002FEULAR classification criteria. These participants will undergo clinical assessments to evaluate disease activity using the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K). Blood indices, including lymphocyte-monocyte ratio (LMR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammatory index (SIRI), will be analyzed to investigate their correlation with disease activity.",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy Controls","This group includes 70 age- and gender-matched healthy individuals without autoimmune diseases or significant comorbidities. Participants will serve as controls for comparison of blood indices, including LMR, NLR, PLR, and SIRI, to establish baseline values and assess differences between healthy individuals and SLE patients.",{"type":16,"investigatorFullName":17,"investigatorTitle":18,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Maha Ibrahim Altayeb Sayed","resident at the internal medicine department","100583112","assessment-of-blood-indices-in-systemic-lupus-erythematosus-100583112",false,"NCT06872086","Assessment of Blood Indices in Systemic Lupus Erythematosus","Assessment of Blood Indices As Predictors of Disease Activity in Systemic Lupus Erythematosus","Inclusion Criteria:\n\n* Patients aged 18 years or older diagnosed with SLE according to the 2019 ACR\u002FEULAR classification criteria.\n* Healthy controls without any autoimmune diseases or significant comorbidities\n\nExclusion Criteria:\n\n* • Patients with other autoimmune diseases (e.g., rheumatoid arthritis, Sjögren's syndrome).\n\n  * Recent infections or acute inflammatory conditions.\n  * Individuals with hematological disorders unrelated to SLE (e.g., leukemia, lymphoma).",true,"FEMALE","18 Years",{"count":30,"type":31},70,"ESTIMATED","1 Month","OBSERVATIONAL","This case-control study aims to explore the relationship between specific blood indices (lymphocyte-monocyte ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune-inflammatory index) and disease activity in patients with systemic lupus erythematosus (SLE).\n\nThe study includes 70 SLE patients and 70 healthy controls, matched for age and gender, recruited from Assiut University Hospital.\n\nDisease activity is assessed using the SLEDAI-2K score, and blood indices are analyzed to determine correlations with disease activity.",[36,37],"SLE","Blood Indices",[36,39,37],"Systemic Lupus Erythematosus","NOT_YET_RECRUITING","2025-03-07",{"date":43,"type":44},"2025-03-12","ACTUAL",{"date":46,"type":31},"2025-05-01",{"date":48,"type":31},"2026-12-30",{"name":5,"class":6}]