[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100173728":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":53,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Nebraska","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Eloquent area tumor",null,"Standard of care with brain mapping, pre-, intra-, and post-operative.",[13],"Diagnostic Test: Brain mapping",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Brain mapping","Brain mapping will be employed pre-, intra-, and post-operatively to evaluate specific functions.",[9],[21],{"name":22,"affiliation":5,"role":23},"Michele Aizenberg, MD","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Dulce Maroni, PhD","CONTACT","402-836-9751","dmaroni@unmc.edu",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Katie Maire, MS","402-559-6895","kmaire@unmc.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"University of Nebraska Medical Center","RECRUITING","Omaha","Nebraska","68198","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-95.94043,41.25626,{"lat":47,"lon":46},[50,51,52],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},{"name":22,"role":23,"phone":10,"phoneExt":10,"email":10},{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100173728","assessment-of-eloquent-function-in-brain-tumor-patients-100173728",false,"NCT01535430","Assessment of Eloquent Function in Brain Tumor Patients","Assessment of Reorganization and Plasticity of Eloquent Function in Patients With Brain Tumors","Inclusion Criteria:\n\n* 19 years and older\n* Brain tumor in or near eloquent brain regions that is appropriate for attempted resection\n* Appropriate body habitus and mental status\u002Fcapacity to participate with non-invasive or invasive mapping\n* Benign or malignant intra-axial brain tumor\n* Primary or metastatic intra-axial brain tumor\n\nExclusion Criteria:\n\n* Any contraindication to MRI (i.e. implanted devices)\n* Inappropriate body habitus or mental status\u002Fcapacity to participate with non-invasive or invasive mapping in a safe and reliable manner\n* Declining to participate\n* Lacks capacity to understand the study or consent for themselves\n* Neurologic status which precludes testing (poor function- not testable)\n* Positive pregnancy test\n* End stage renal disease or severe renal dysfunction","ALL","19 Years",{"count":65,"type":66},75,"ESTIMATED","OBSERVATIONAL","Purpose of the study:\n\nAIM 1: Prospectively collect pre-operative \\[functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)\\] and intra-operative mapping data in patients with intra-axial brain tumors to assess how well each modality predicts the location of eloquent brain function. In addition, each modality will be compared with the other.\n\nAIM 2: Assess reorganization of eloquent brain function and plasticity in patients with intra-axial brain tumors. This will be accomplished by prospectively collecting post-operative mapping studies and neuropsychological tests to compare them to prior mapping studies as stated above.",[70,71],"Primary Brain Tumor","Metastatic Brain Tumor",[73,74],"brain mapping","brain tumor","2026-01-09",{"date":77,"type":78},"2026-01-13","ACTUAL",{"date":80,"type":78},"2012-01-31",{"date":82,"type":66},"2027-12",{"name":5,"class":6},1]