[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623312":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":24,"locations":32,"responsibleParty":51,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Gazi University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients group",null,"This group includes patients who have undergone mitral stenosis intervention for mitral stenosis. Patients exercise capacity using Cardiopulmonary Exercise Test (CPET), muscle oxygenation with a near-infrared spectroscopy device, respiratory functions with a spirometer, respiratory muscle strength with a mouth pressure measurement device, respiratory muscle endurance with an incremental threshold loading respiratory muscle endurance test, aortic stiffness with an arteriograph, physical activity level with a multisensor physical activity monitor and quality of life with the SF-36 Short Form will be evaluated.",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy Controls Group","Healthy controls will be evaluated for exercise capacity with the Cardiopulmonary Exercise Test (CPET), muscle oxygenation with a near-infrared spectroscopy device, respiratory functions with a spirometer, respiratory muscle strength with a mouth pressure measurement device, respiratory muscle endurance with an incremental threshold loading respiratory muscle endurance test, aortic stiffness with an arteriograph, physical activity level with a multisensor physical activity monitor, and quality of life with the SF-36 Short Form.",[16,19,22],{"name":17,"affiliation":5,"role":18},"Ebrar TÜLÜMENOĞLU, Pt","STUDY_CHAIR",{"name":20,"affiliation":5,"role":21},"Özden SEÇKİN GÖBÜT, Dr","PRINCIPAL_INVESTIGATOR",{"name":23,"affiliation":5,"role":21},"Serkan ÜNLÜ, Dr",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Meral BOŞNAK GÜÇLÜ, Prof. Dr.","CONTACT","+90(312)2162647","meralbosnak@gazi.edu.tr",{"name":17,"role":27,"phone":10,"phoneExt":10,"email":31},"25854401007@gazi.edu.tr",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":10,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit","RECRUITING","Ankara","Çankaya","06490","Turkey (Türkiye)",{"type":41,"coordinates":42},"Point",[43,44],32.85427,39.91987,{"lat":44,"lon":43},[47,48],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":17,"role":27,"phone":49,"phoneExt":10,"email":50},"+905434157799","ebrar.tulumenoglu@gmail.com",{"type":21,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Meral Boşnak Güçlü","Prof. Dr.","100623312","assessment-of-exercise-capacity-muscle-oxygenation-and-aortic-stiffness-in-patients-with-mitral-stenosis-100623312",false,"NCT07394998","Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis","Comparison of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With a History of Mitral Valve Intervention for Mitral Stenosis With Healthy Subjects","Inclusion Criteria:\n\nPatients;\n\n* Between the ages of 18-80\n* Patients who have undergone mitral valve intervention due to mitral stenosis\n* At least 3 months have passed since the intervention\n\nHealthy controls;\n\n* Between the ages of 18 and 80\n* Agreeing to participate voluntarily in the study\n\nExclusion Criteria:\n\nPatients;\n\n* Patients who have undergone aortic valve intervention other than mitral valve intervention\n* Acute infection\n* Orthopedic, neurological or psychological disorders that will affect functional capacity\n\nHealthy Controls;\n\n* diagnosed chronic disease,\n* acute infection\n* A smoking history of at least 10 packs×years or more",true,"ALL","18 Years","80 Years",{"count":66,"type":67},40,"ESTIMATED","OBSERVATIONAL","Heart valve diseases are the most common cause of mortality and morbidity after coronary artery disease, hypertension, and heart failure. In patients with mitral stenosis, the narrowed valve restricts blood flow, causing symptoms such as shortness of breath, fatigue, exertional dyspnea, orthopnea, and paroxysmal nocturnal dyspnea. These patients may experience decreased exercise capacity and physical activity levels, deterioration in quality of life, and deterioration in respiratory function. When reviewing the literature, we see that the study groups evaluating these factors are generally not homogeneous, and most studies conducted in patients with mitral stenosis evaluate patients who have undergone percutaneous mitral balloon valvuloplasty.",[71],"Mitral Stenosis",[73,74,75,76,77],"cardiopulmonary exercise test","aortic stiffness","muscle oxygenation","physical activity","mitral stenosis","2026-01-31",{"date":80,"type":81},"2026-02-06","ACTUAL",{"date":83,"type":81},"2025-01-13",{"date":85,"type":67},"2026-07",{"name":5,"class":6},1]