[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622537":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":60,"collaborators":62,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":28,"enrollmentInfo":75,"targetDuration":28,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":89,"whyStopped":28,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Université Catholique de Louvain","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute coronary syndrome","EXPERIMENTAL","This arm includes patients undergoing coronary angiography with a final diagnostic of acute coronary syndrome. The intervention administered is an arterial blood sample from the sheath at the beginning of the examination.",[13],"Biological: Arterial blood sample",{"label":15,"type":10,"description":16,"interventionNames":17},"Chronic coronary syndrome","This arm includes patients undergoing coronary angiography with a final diagnostic of chronic coronary syndrome. The intervention administered is an arterial blood sample from the sheath at the beginning of the examination.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Control","This arm includes patients undergoing coronary angiography with a final diagnostic of non significant coronary disease. The intervention administered is an arterial blood sample from the sheath at the beginning of the examination.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"BIOLOGICAL","Arterial blood sample","An arterial blood sample will be obtained at the beginning of the coronary angiography by using the arterial sheat in place.",[9,15,19],null,[30],{"name":31,"affiliation":32,"role":33},"Christophe Beauloye, Medical Degree","Cliniques universitaires Saint-Luc- Université Catholique de Louvain","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":28,"email":39},"Louis Charki, Medical Degree","CONTACT","+3224362014","louis.charki@uclouvain.be",[41],{"facility":42,"status":28,"city":43,"state":28,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Cliniques Universitaires Saint-Luc","Brussels","1200","Belgium","BE",{"type":48,"coordinates":49},"Point",[50,51],4.34878,50.85045,{"lat":51,"lon":50},[54,55,56,58],{"name":36,"role":37,"phone":38,"phoneExt":28,"email":39},{"name":31,"role":33,"phone":28,"phoneExt":28,"email":28},{"name":36,"role":57,"phone":28,"phoneExt":28,"email":28},"SUB_INVESTIGATOR",{"name":59,"role":57,"phone":28,"phoneExt":28,"email":28},"Shakeel Kautbally, Medical Degree",{"type":61,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[63],{"name":64,"class":6},"Fonds National de la Recherche Scientifique","100622537","assessment-of-garp-expression-in-acute-and-chronic-coronary-syndrome-100622537",false,"NCT07384910","Assessment of GARP Expression in Acute and Chronic Coronary Syndrome","Assessment of GARP Expression and Inflammatory Cytokines in Acute and Chronic Coronary Syndrome","GARP-CS","Inclusion Criteria:\n\n* Older than 18 years\n* Able to give informed consent\n* Undergoing coronary angiography.\n\nExclusion Criteria:\n\n* Patients younger than 18 years\n* Unable to give consent\n* Pregnancy\n* Dialysis","ALL","18 Years",{"count":76,"type":77},600,"ESTIMATED","INTERVENTIONAL",[80],"NA","The leading cause of death is cardiovascular diseases in occidental countries. Of those, atherosclerosis is the major contributor to this burden being notably responsible for strokes and myocardial infarctions. The genesis of atherosclerosis is linked to both lipid accumulation and inflammation in the vascular wall of major arteries. One of the major pathways of inflammation is the TGF-beta axis which is at least partially regulated by the GARP protein. It has been investigated mostly in cancer biology but data in cardiovascular disease is lacking. Thus, the investigators aim to characterize the contribution of this protein by investigating its expression in circulating blood cells from patients with an acute or chronic coronary syndrom. The main cells expressing the GARP protein are the platelets and the T regulating cells which will be the main focus.",[83],"Atheroma; Heart",[85,86,87,88],"Atheroma","Atherosclerosis","GARP","LRRC32","NOT_YET_RECRUITING","2026-02-12",{"date":92,"type":93},"2026-02-17","ACTUAL",{"date":95,"type":77},"2026-02",{"date":97,"type":77},"2028-01",{"name":5,"class":6},1]