[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640306":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":32,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Kaohsiung Armed Forces General Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hypertensive Patients With Suspected OSA",null,"Adult patients aged 18 to 65 years with diagnosed hypertension or resistant hypertension and high risk of obstructive sleep apnea (STOP-Bang score ≥3). Participants will undergo 24-hour Holter monitoring for heart rate variability (HRV) assessment and overnight polysomnography (PSG) to evaluate sleep parameters and OSA severity. Clinical data including blood pressure and relevant medical history will be collected for analysis.",[13],"Diagnostic Test: Polysomnography",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Polysomnography","Overnight polysomnography (PSG) will be performed to evaluate sleep parameters and determine the severity of obstructive sleep apnea.",[9],[21],{"name":22,"affiliation":5,"role":23},"Yung Kuo Lee, PhD","PRINCIPAL_INVESTIGATOR",[25,29],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","+886910977485","abstyle0204@gmail.com",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":28},"Chih-Hsuan Chang, MS","+886905163699",[33],{"facility":5,"status":34,"city":35,"state":36,"zip":10,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Kaohsiung City","Kaohsiung","Taiwan","TW",{"type":40,"coordinates":41},"Point",[42,43],120.31333,22.61626,{"lat":43,"lon":42},[46,48],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":47},"yungkuolee@gmail.com",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":28},{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100640306","assessment-of-heart-rate-variability-for-predicting-obstructive-sleep-apnea-in-patients-with-hypertension-100640306",false,"NCT07603583","Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension","The Exploration of the Relationship Between Hypertension and Sleep Apnea Through Heart Rate Variability, and the Subsequent Investigation of Non-pharmacological and Pharmacological Treatments","HRV-OSA-HTN","Inclusion Criteria:\n\n* Age 18 to 65 years\n* Diagnosed hypertension or resistant hypertension\n* STOP-Bang score ≥3 indicating high risk of obstructive sleep apnea\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Refusal to undergo HRV monitoring or polysomnography\n* Unstable medical condition that may interfere with study participation\n* Inability to comply with study procedures","ALL","18 Years","65 Years",{"count":63,"type":64},100,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.\n\nHypertensive patients at high risk for OSA will undergo 24-hour Holter electrocardiogram monitoring to assess HRV parameters, along with overnight polysomnography (PSG) to determine OSA severity. The study will analyze the association between HRV indices and the apnea-hypopnea index (AHI), and develop predictive models using machine learning techniques.\n\nIn addition, patients diagnosed with OSA will be followed after treatment, and changes in HRV and blood pressure will be evaluated to assess treatment effects and autonomic function recovery.\n\nThe results of this study may provide a cost-effective and clinically applicable approach for early detection, risk stratification, and management of OSA in patients with hypertension.",[68,69],"Obstructive Sleep Apnea","Hypertension",[71,17,72,73,74],"Heart Rate Variability","CPAP","Sleep Apnea Screening","Machine Learning","2026-05-18",{"date":77,"type":78},"2026-05-22","ACTUAL",{"date":80,"type":78},"2026-04-30",{"date":82,"type":64},"2026-12-31",{"name":5,"class":6},1]