[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563266":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":30,"centralContacts":35,"locations":46,"responsibleParty":63,"collaborators":45,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":45,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":45,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":45,"overallStatus":49,"whyStopped":45,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Future University in Egypt","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"hydroxyapatite","EXPERIMENTAL","using hydroxyapatite as a pulpotomy agent and reviewing its clinical and radiographic performance compared to the other groups",[13],"Procedure: pulpotomy",{"label":15,"type":10,"description":16,"interventionNames":17},"L-PRF","using L-PRF as a pulpotomy agent and assessing the clinical and radiographic result compared to other groups",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"L-PRF combined with Nano-hydroxyapatite","using the combined material (nanohydroxyapatite mixed to L-PRF ) and assessing the clinical and radiographic result compared to other groups",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","pulpotomy","removal of the coronal pulp tissue and preservation of the radicular portion to ensure continuation of growth and vitality of tooth structure",[15,19,9],[29],"vital pulp therapy",[31],{"name":32,"affiliation":33,"role":34},"wael K hussein, professor","future","STUDY_DIRECTOR",[36,42],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"nada A metwally, master","CONTACT","01122289353","+02","nadaaymaan55@gmail.com",{"name":43,"role":38,"phone":44,"phoneExt":40,"email":45},"toka A metwally, bachelor's","01068681660",null,[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"future university in Egypt","RECRUITING","Cairo","New Cairo","11835","Egypt","EG",{"type":56,"coordinates":57},"Point",[58,59],31.24967,30.06263,{"lat":59,"lon":58},[62],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":45,"oldOrganization":45},"PRINCIPAL_INVESTIGATOR","Nada Ayman El-Sayed Ibraim","principal investigator","100563266","assessment-of-l-prf-nanohydroxyapatite-combined-with-l-prf-using-pulpotomy-in-mature-mandibular-first-molars-100563266",false,"NCT06613932","Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars","Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite Material Combined With L-PRF Scaffold in Vital Pulp Therapy. Treatments in Mandibular First Molars With Closed Apices \"Randomized Controlled Trial\"","Inclusion criteria:\n\nPatients should be free from any systemic disease. Patients of either gender aged from 15-30. Patients will agree to the consent and will commit to a follow-up period. Soft tissues around the tooth are normal with no swelling or sinus tract. The tooth is restorable tooth has signs and symptoms of irreversible pulpitis of the mature root The tooth doesn\\'t contain any internal or external resorption or periapical lesions.\n\nThe tooth should give a positive response to the cold test.\n\nExclusion criteria:\n\nPregnant and lactating females. Patients with Mental disturbance. Patients who could\u002Fwould not participate in a 6-month follow-up. A tooth with immature roots. Patients with necrotic pulp.• tooth with periapical lesions or infections. Soft tissue having fistula or swelling Homoeostasis after 10 minutes can not be controlled after total pulpotomy",true,"ALL","15 Years","30 Years",{"count":79,"type":80},45,"ESTIMATED","INTERVENTIONAL",[83],"NA","Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.",[86],"Irreversible Pulpitis","2024-09-25",{"date":89,"type":90},"2024-09-26","ACTUAL",{"date":92,"type":90},"2023-10-30",{"date":94,"type":80},"2024-10-30",{"name":5,"class":6},1]