[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100540464":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":90,"collaborators":93,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":105,"sex":106,"minAge":107,"maxAge":25,"enrollmentInfo":108,"targetDuration":25,"studyType":111,"phases":112,"briefSummary":114,"conditions":115,"keywords":121,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Technische Universität Dresden","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Elastography","EXPERIMENTAL","Collection of ultrasound data and elastography data from patients who were clinically planned for elastography",[13],"Device: Collection of elastography data",{"label":15,"type":10,"description":16,"interventionNames":17},"Focal lesion","Collection of ultrasound data of the suspected lesion and a definitive diagnosis based on either normal ultrasound investigation or if not sufficient additional investigations like CEUS, Biopsy, MRI or CT. This further investigation should be in accordance to normal clinical routine of the centers to differentiate focal lesions.",[18],"Device: Collection of ultrasonic raw data",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Collection of elastography data","patients who are scheduled for an elastography for clinical reasons usually receive an ultrasound scan in which the b-mode images of the liver tissue are collected. In this study additional radiofrequency data is collected through a software access.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Collection of ultrasonic raw data","Patients who are transferred to the ultrasound departement due to suspicious focal lesions receive an ultrasonic investigation including the acquisition of raw data and extracting a definitive diagnose from the following clinical routine investigation, depending on the standards of the participating center",[15],[31],{"name":32,"affiliation":33,"role":34},"Moritz Herzog, MD","University Hospital Dresden","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","0049 351 458 11501","moritz.herzog@ukdd.de",[41,57,66,78],{"facility":42,"status":43,"city":44,"state":25,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"University Hospital","RECRUITING","Dresden","01307","Germany","DE",{"type":49,"coordinates":50},"Point",[51,52],13.73832,51.05089,{"lat":52,"lon":51},[55],{"name":32,"role":37,"phone":56,"phoneExt":25,"email":39},"0049 15785617350",{"facility":58,"status":43,"city":44,"state":25,"zip":25,"country":46,"countryCode":47,"cosmosGeoPoint":59,"geoPoint":61,"contacts":62},"Diakonissen Hospital Dresden",{"type":49,"coordinates":60},[51,52],{"lat":52,"lon":51},[63],{"name":64,"role":37,"phone":25,"phoneExt":25,"email":65},"Matthias Ziesch, MD","Matthias.Ziesch@diako-dresden.de",{"facility":67,"status":43,"city":68,"state":25,"zip":25,"country":46,"countryCode":47,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"University Hospital Halle (Saale)","Halle",{"type":49,"coordinates":70},[71,72],11.97947,51.48158,{"lat":72,"lon":71},[75],{"name":76,"role":37,"phone":25,"phoneExt":25,"email":77},"Valentin Blank, MD","Valentin.Blank@uk-halle.de",{"facility":79,"status":43,"city":80,"state":25,"zip":25,"country":46,"countryCode":47,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"University Hospital Leipzig","Leipzig",{"type":49,"coordinates":82},[83,84],12.37129,51.33962,{"lat":84,"lon":83},[87],{"name":88,"role":37,"phone":25,"phoneExt":25,"email":89},"Thomas Karlas, MD","Thomas.Karlas@medizin.uni-leipzig.de",{"type":34,"investigatorFullName":91,"investigatorTitle":92,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Moritz Herzog","Principal Investigator",[94,95],{"name":33,"class":6},{"name":96,"class":6},"University of Leipzig","100540464","assessment-of-liver-diseases-using-a-deep-learning-approach-based-on-ultrasound-rf-data-100540464",false,"NCT06317181","Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data","Acquisition and Frequency Spectroscopic Evaluation of Broadband Clinical Ultrasound Raw Data for Liver Cirrhosis and Focal Pathologies Using Neural Networks for Tissue and Pathology Differentiation","LivSPECTRUS","Inclusion Criteria:\n\n* scheduled for an ultrasound investigation by an independent physician\n* signed declaration of consent\n\nExclusion Criteria:\n\n* smaller interventions in the same liver during the last 2 Week (for example liver biopsy)\n* contrast enhanced ultrasound less than a day ago\n* major intervention at the liver (for example partial resection)",true,"ALL","18 Years",{"count":109,"type":110},200,"ESTIMATED","INTERVENTIONAL",[113],"NA","The goal of this clinical trial is to test the performance of neuronal networks trained on ultrasonic raw Data (=radiofrequency data) for the assessment of liver diseases in patients undergoing a clinical ultrasound examination. The general feasibility is currently evaluated in a retrospective cohort.\n\nThe main questions the study aims to answer are:\n\n* Can a neuronal network trained on RF Data perform equally good as elastography in the assessment of diffuse liver diseases?\n* Can a neuronal network trained on RF Data perform better than a neuronal network trained on b-mode images in the assessment of diffuse liver diseases?\n* Can a neuronal network trained on RF Data distinguish focal pathologies in the liver from healthy tissue?\n\nTo answer these questions participants with a clinically indicated fibroscan will undergo:\n\n* a clinical elastography in Case ob suspected diffuse liver disease\n* a reliable ground truth (if normal ultrasound is not sufficient e.g. contrast enhanced ultrasound, biopsy, MRI or CT) in case of focal liver diseases, depending on the standard routine of the participating center\n* a clinical ultrasound examination during which b-mode images and the corresponding RF-Data sets are captured",[116,117,118,119,120],"Artificial Intelligence","Ultrasonography","Elasticity Imaging Techniques","Liver Diseases","Metastasis to Liver",[122,123],"Quantitative Ultrasound","Radiofrequency Data","2025-08-18",{"date":126,"type":127},"2025-08-20","ACTUAL",{"date":129,"type":127},"2024-04-01",{"date":131,"type":110},"2025-12",{"name":5,"class":6},4]