[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601118":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":33,"locations":23,"responsibleParty":43,"collaborators":23,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":23,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":23,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":23,"overallStatus":67,"whyStopped":23,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":23},{"fullName":5,"class":6},"Menoufia University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Group A - Conventional Treatment (Control Group):","Socket debridement and irrigation with normal saline.\n\nPain management using Diclofenac potassium (50 mg TID).\n\nFollow-up at day 2, 3, 7, 10, and 14.\n\nHome care: saline mouth rinse.",[12],"Other: Irrigation with saline",{"label":14,"type":6,"description":15,"interventionNames":16},"Group B-Ozone Therapy Group","Socket debridement and irrigation with ozonated water.\n\nApplication of ozonated gel into the socket using syringe with fine-tip applicator.\n\nPain management using Diclofenac potassium (50 mg TID).\n\nPatients instructed to use ozonated water and gel at home daily.\n\nFollow-up at day 2, 3, 7, 10, and 14.",[17],"Other: Topical Ozone Therapy",[19,24],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Topical Ozone Therapy","The intervention involves local application of ozone in two forms:\n\nOzonated Water - used for irrigation of the extraction socket.\n\nOzonated Gel - applied topically inside the socket to promote healing and reduce pain.\n\nBoth are used after socket debridement and bleeding provocation, followed by standard analgesic administration (Diclofenac potassium).",[14],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Irrigation with saline","The intervention involves irrigation with saline",[9],[29],{"name":30,"affiliation":31,"role":32},"Mohammed El-Sawy, PhD","Menoufia Universityt","STUDY_CHAIR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":23,"email":38},"Mohammed A. El-Sawy, PhD","CONTACT","00201061314522","Dr_sawy@windowslive.com",{"name":40,"role":36,"phone":41,"phoneExt":23,"email":42},"Mohammed T. Khater, PhD","00201003854552","MohamedKhaterdentalsmile1234@gmail.com",{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Mohammed El-Sawy","Clinical Professor and principle investigator","100601118","assessment-of-ozone-therapy-for-management-of-post-extraction-localized-alveolar-osteitis-100601118",false,"NCT07106333","Assessment of Ozone Therapy for Management of Post-Extraction Localized Alveolar Osteitis","Management of Post-Extraction Localized Alveolar Osteitis","Inclusion Criteria:\n\nAge: 18-60 years.\n\nPatients undergoing simple (non-surgical) extractions.\n\nMedically healthy individuals.\n\nExclusion Criteria:\n\nPatients already treated for AO.\n\nPresence of systemic diseases affecting healing.\n\nSevere infections or facial swelling.\n\nIncomplete follow-up.\n\nContraindications to ozone therapy: G6PD deficiency, hyperthyroidism, malignant hypertension, recent myocardial infarction.",true,"ALL","20 Years","50 Years",{"count":59,"type":60},40,"ESTIMATED","INTERVENTIONAL",[63],"NA","This clinical study investigates the effectiveness of ozone therapy in comparison to conventional treatment for alveolar osteitis (AO), a common painful complication following tooth extraction. Forty patients diagnosed with dry socket will be randomly divided into two groups. Group A will receive traditional treatment with normal saline irrigation and analgesics, while Group B will be treated using ozonated water, ozonated gel, and analgesics. Both groups will be monitored over a two-week period to evaluate pain levels, healing progression, and other clinical indicators. The study aims to assess the palliative and regenerative benefits of ozone therapy in managing AO, potentially offering an alternative to conventional symptomatic treatments.",[66],"Alveolar Osteitis","NOT_YET_RECRUITING","2025-07-29",{"date":70,"type":71},"2025-08-06","ACTUAL",{"date":73,"type":60},"2025-08-01",{"date":75,"type":60},"2026-02-01",{"name":5,"class":6}]