[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632380":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":39,"collaborators":42,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"West Kazakhstan Marat Ospanov Medical University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group\u002FCohort Label T2DM without EPI by fecal elastase-1",null,"Adults with type 2 diabetes mellitus classified as not having exocrine pancreatic insufficiency according to fecal elastase-1 levels.",{"label":13,"type":10,"description":14,"interventionNames":10},"Group\u002FCohort Label T2DM without EPI by PEI-Q","Adults with type 2 diabetes mellitus classified as not having exocrine pancreatic insufficiency according to Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) results.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Mengtay S Makashova","CONTACT","+77058440060","ersultanbeknur@gmail.com",[22],{"facility":23,"status":24,"city":25,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"Outpatient clinics of Aktobe region, West Kazakhstan Marat Ospanov Medical University","RECRUITING","Aktobe","030019","Kazakhstan","KZ",{"type":30,"coordinates":31},"Point",[32,33],57.20718,50.27969,{"lat":33,"lon":32},[36],{"name":37,"role":18,"phone":38,"phoneExt":10,"email":20},"Mengtay Makashova","87058440060",{"type":40,"investigatorFullName":37,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","phd candidate",[43],{"name":44,"class":6},"Universitatea de Stat de Medicina si Farmacie Nicolae Testemiţanu","100632380","assessment-of-pancreatic-dysfunction-in-patients-with-type-2-diabetes-100632380",false,"NCT07512934","Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes","Integrated Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes: a Cross-sectional Study Protocol","T3cDM-AKT","Inclusion Criteria:\n\n* • adult patients of Kazakh nationality aged 18 to 74 years\n* diagnosis of T2DM established according to ADA criteria and documented in medical records\n* disease duration ≤5 years\n* absence of ketoacidosis episodes within the last 6 months\n\nExclusion Criteria:\n\n* positive anti-glutamic acid decarboxylase antibodies (anti-GAD65);\n* acute or chronic infections affecting metabolic status within the previous 4 weeks;\n* any history of malignant neoplasms;\n* pregnancy or lactation;\n* previously diagnosed type 1 diabetes mellitus or other specific types of diabetes;\n* severe decompensated chronic diseases;\n* conditions associated with systemic fibrosis (e.g., liver cirrhosis or autoimmune diseases);\n* refusal to participate.","ALL","18 Years","74 Years",{"count":57,"type":58},310,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to better understand how the pancreas works in adults with type 2 diabetes. The study focuses on both hormone production (endocrine function) and digestive function (exocrine function) of the pancreas.\n\nThe main questions it aims to answer are:\n\n* Can problems with the pancreas help identify a different type of diabetes called pancreatogenic diabetes?\n* How are blood markers and pancreas structure related to pancreatic function?\n\nParticipants will:\n\n* Have blood tests to measure glucose, insulin, and other markers\n* Provide a stool sample to assess digestive function\n* Undergo an ultrasound examination of the pancreas\n* Answer questions about digestive symptoms\n\nThe study will take place during a single visit in outpatient clinics.",[62,63,64],"Pancreatogenic Diabetes Mellitus","Type 2 Diabetes Mellitus (T2DM)","Exocrine Pancreatic Insufficiency (EPI)",[66,67,68,69,70,71,72,73,74],"Type 3c diabetes","Pancreatogenic diabetes","Fecal elastase-1","TGF-beta1","Adiponectin","IL-1 receptor antagonist","Pancreatic ultrasound","PEI-Q","Type 2 Diabetes Mellitus","2026-04-02",{"date":77,"type":78},"2026-04-06","ACTUAL",{"date":80,"type":78},"2025-07-07",{"date":82,"type":58},"2026-12-01",{"name":5,"class":6},1]