[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628353":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":47,"collaborators":7,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":7,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":7,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"LMU Klinikum","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Stefan Brunner, MD","CONTACT","+49 89 4400 0","Stefan.Brunner@med.uni-muenchen.de",[15,32],{"facility":16,"status":17,"city":18,"state":19,"zip":20,"country":21,"countryCode":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":29},"LMU University Hospital","RECRUITING","Munich","Bavaria","80336","Germany","DE",{"type":24,"coordinates":25},"Point",[26,27],11.57549,48.13743,{"lat":27,"lon":26},[30],{"name":31,"role":11,"phone":12,"phoneExt":7,"email":13},"Brunner, MD",{"facility":33,"status":17,"city":34,"state":7,"zip":7,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":41,"contacts":42},"Central Hospital of Bolzano","Bolzano","Italy","IT",{"type":24,"coordinates":38},[39,40],11.33982,46.49067,{"lat":40,"lon":39},[43],{"name":44,"role":11,"phone":45,"phoneExt":7,"email":46},"Matthias Unterhuber, MD","+39 0471 439 950","kardiologie.bz@sabes.it",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Prof. Dr. Stefan Brunner","Principal Investigator","100628353","assessment-of-physical-activity-and-cardiovascular-outcomes-in-patients-with-chronic-heart-failure-100628353",false,"NCT07460531","Assessment of Physical Activity and Cardiovascular Outcomes in Patients With Chronic Heart Failure","SOPHIE","Inclusion Criteria:\n\n* Heart failure NT-proBNP \\>600 pg\u002Fml (at least once in the history) NYHA-Class II-IV HFrEF - heart failure with reduced ejection fraction; LVEF ≤40% or HFmrEF - heart failure with mildly reduced ejection fraction; LVEF 41% - 49% or HFpEF - heart failure with preserved ejection fraction; LVEF ≥50%\n* Age ≥18 years old\n* Willingness to participate in the study, confirmed by a signed informed consent form\n* Ownership of a pedometer (e.g. smartwatch, activity tracker, smartphone-app, analogical pedometer)\n\nExclusion Criteria:\n\n* Disease or disability that prevents physical activity\n* Hospitalisation due to heart failure within the last three months","ALL","18 Years",{"count":61,"type":62},2000,"ESTIMATED","3 Years","OBSERVATIONAL","SOPHIE is a prospective, multicentre, observational cohort study aiming to enrol 2,000 CHF patients. Baseline assessments include validated PA questionnaires (GPAQ, IPAQ, KCCQ) and seven-day step counts from commercially available pedometer devices. Follow-up is conducted every six months via telephone, repeating PA assessments and recording cardiovascular events, hospitalisations, and patient-reported outcomes.",[67],"Heart Failure","2026-03-09",{"date":70,"type":71},"2026-03-11","ACTUAL",{"date":73,"type":71},"2025-02-01",{"date":75,"type":62},"2031-06-30",{"name":5,"class":6},2]